ID E9PJC7_HUMAN Unreviewed; 157 AA.
AC E9PJC7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=CD82 molecule {ECO:0000313|Ensembl:ENSP00000433788.1};
DE Flags: Fragment;
GN Name=CD82 {ECO:0000313|Ensembl:ENSP00000433788.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000433788.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000433788.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000433788.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840}.
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DR EMBL; AC010768; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; E9PJC7; -.
DR SMR; E9PJC7; -.
DR SwissPalm; E9PJC7; -.
DR MassIVE; E9PJC7; -.
DR MaxQB; E9PJC7; -.
DR PeptideAtlas; E9PJC7; -.
DR ProteomicsDB; 21097; -.
DR Antibodypedia; 3743; 684 antibodies from 43 providers.
DR Ensembl; ENST00000530601.1; ENSP00000433788.1; ENSG00000085117.12.
DR UCSC; uc058ara.1; human.
DR HGNC; HGNC:6210; CD82.
DR VEuPathDB; HostDB:ENSG00000085117; -.
DR GeneTree; ENSGT00940000158481; -.
DR HOGENOM; CLU_055524_4_1_1; -.
DR ChiTaRS; CD82; human.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000085117; Expressed in olfactory bulb and 194 other cell types or tissues.
DR ExpressionAtlas; E9PJC7; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282:SF44; CD82 ANTIGEN; 1.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|EPD:E9PJC7,
KW ECO:0007829|MaxQB:E9PJC7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 157
FT /evidence="ECO:0000313|Ensembl:ENSP00000433788.1"
SQ SEQUENCE 157 AA; 17332 MW; E279738E1FD1FD8C CRC64;
MEILGAVILG FGVWILADKS SFISVLQTSS SSLRMGAYVF IGVGAVTMLM GFLGCIGAVN
EVRCLLGLYF AFLLLILIAQ VTAGALFYFN MGKLKQEMGG IVTELIRDYN SSREDSLQDA
WDYVQAQVKC CGWVSFYNWT DNAELMNRPE VTYPCSC
//
