ID E9PNV7_HUMAN Unreviewed; 141 AA.
AC E9PNV7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000437134.1};
DE Flags: Fragment;
GN Name=ZNF707 {ECO:0000313|Ensembl:ENSP00000437134.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000437134.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000437134.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16421571; DOI=10.1038/nature04406;
RA Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA Platzer M., Shimizu N., Lander E.S.;
RT "DNA sequence and analysis of human chromosome 8.";
RL Nature 439:331-335(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000437134.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC105219; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Antibodypedia; 7422; 116 antibodies from 22 providers.
DR Ensembl; ENST00000534303.5; ENSP00000437134.1; ENSG00000181135.16.
DR Ensembl; ENST00000631634.1; ENSP00000488006.1; ENSG00000274352.4.
DR UCSC; uc064rdd.1; human.
DR HGNC; HGNC:27815; ZNF707.
DR VEuPathDB; HostDB:ENSG00000181135; -.
DR GeneTree; ENSGT00940000164666; -.
DR HOGENOM; CLU_1829765_0_0_1; -.
DR OMA; EQWDELW; -.
DR Proteomes; UP000005640; Chromosome 8.
DR Bgee; ENSG00000181135; Expressed in primordial germ cell in gonad and 99 other cell types or tissues.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF90; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR SMART; SM00349; KRAB; 1.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:E9PNV7,
KW ECO:0007829|PeptideAtlas:E9PNV7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 8..79
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT REGION 71..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 141
FT /evidence="ECO:0000313|Ensembl:ENSP00000437134.1"
SQ SEQUENCE 141 AA; 16425 MW; 58DE28D57EB10F0A CRC64;
MDMAQEPVTF RDVAIYFSRE EWACLEPSQR ALYRDVMLDN FSSVAALGFC SPRPDLVSRL
EQWEEPWVED RERPEFQAVQ RGPRPGARKS ADPKRPCDHP AWAHKKTHVR RERAREGSSF
RKGFRLDTDD GQLPRAAPER T
//
