GenomeNet

Database: UniProt
Entry: E9PQR6_HUMAN
LinkDB: E9PQR6_HUMAN
Original site: E9PQR6_HUMAN 
ID   E9PQR6_HUMAN            Unreviewed;       173 AA.
AC   E9PQR6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   11-DEC-2019, entry version 53.
DE   SubName: Full=ETS homologous factor {ECO:0000313|Ensembl:ENSP00000434395};
DE   Flags: Fragment;
GN   Name=EHF {ECO:0000313|Ensembl:ENSP00000434395};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434395, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434395, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434395}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC087783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   MaxQB; E9PQR6; -.
DR   PeptideAtlas; E9PQR6; -.
DR   PRIDE; E9PQR6; -.
DR   ProteomicsDB; 23096; -.
DR   Ensembl; ENST00000525253; ENSP00000434395; ENSG00000135373.
DR   UCSC; uc058ahw.1; human.
DR   EuPathDB; HostDB:ENSG00000135373.12; -.
DR   HGNC; HGNC:3246; EHF.
DR   OpenTargets; ENSG00000135373; -.
DR   eggNOG; KOG3804; Eukaryota.
DR   eggNOG; ENOG4111K4J; LUCA.
DR   GeneTree; ENSGT00940000159310; -.
DR   ChiTaRS; EHF; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000135373; Expressed in 149 organ(s), highest expression level in parotid gland.
DR   ExpressionAtlas; E9PQR6; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:HPA.
DR   GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030855; P:epithelial cell differentiation; IEA:InterPro.
DR   GO; GO:0050673; P:epithelial cell proliferation; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR033071; EHF.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR11849:SF171; PTHR11849:SF171; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0000213|MaxQB:E9PQR6,
KW   ECO:0000213|PeptideAtlas:E9PQR6, ECO:0000213|ProteomicsDB:E9PQR6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          29..115
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   NON_TER         173
FT                   /evidence="ECO:0000313|Ensembl:ENSP00000434395"
SQ   SEQUENCE   173 AA;  19819 MW;  EBB4C8989998C0E4 CRC64;
     MILEGGGVMN LNPGNNLLHQ PPAWTDSYST CNVSSGFFGG QWHEIHPQYW TKYQVWEWLQ
     HLLDTNQLDA NCIPFQEFDI NGEHLCSMSL QEFTRAAGTA GQLLYSNLQH LKWNGQCSSD
     LFQSTHNVIV KTEQTEPSIM NTWKDENYLY DTNYGSTVDL LDSKTFCRAQ ISM
//
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