ID E9PVX4_MOUSE Unreviewed; 514 AA.
AC E9PVX4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Zona pellucida 3 receptor {ECO:0000313|Ensembl:ENSMUSP00000118784.2};
GN Name=Zp3r {ECO:0000313|Ensembl:ENSMUSP00000118784.2,
GN ECO:0000313|MGI:MGI:104965};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000118784.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000118784.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118784.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000118784.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118784.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; E9PVX4; -.
DR SMR; E9PVX4; -.
DR ProteomicsDB; 355066; -.
DR Ensembl; ENSMUST00000142416.2; ENSMUSP00000118784.2; ENSMUSG00000042554.11.
DR AGR; MGI:104965; -.
DR MGI; MGI:104965; Zp3r.
DR VEuPathDB; HostDB:ENSMUSG00000042554; -.
DR GeneTree; ENSGT00940000154640; -.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000042554; Expressed in spermatid and 13 other cell types or tissues.
DR ExpressionAtlas; E9PVX4; baseline and differential.
DR CDD; cd00033; CCP; 6.
DR Gene3D; 1.20.5.3730; -; 1.
DR Gene3D; 2.20.28.230; -; 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR InterPro; IPR040514; C4bp_oligo.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF565; ZONA PELLUCIDA SPERM-BINDING PROTEIN 3 RECEPTOR; 1.
DR Pfam; PF18453; C4bp_oligo; 1.
DR Pfam; PF00084; Sushi; 6.
DR SMART; SM00032; CCP; 6.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 6.
DR PROSITE; PS50923; SUSHI; 6.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302};
KW Proteomics identification {ECO:0007829|ProteomicsDB:E9PVX4};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..514
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003245624"
FT DOMAIN 32..93
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 94..155
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 156..215
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 216..282
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 283..348
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 389..446
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 186..213
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 514 AA; 57999 MW; FBCC9EB1471DBA71 CRC64;
MITWSFIELW RTSHSTLFQM TLATVLMAPV LGDCGPPPLL PFASPTNQLY ESTTFPSGTV
LKYTCHHGFK RVNSSHLSCD ENGSWVYSTF CARKRCKNPG ELVNGKVEIP SDLLVGSIIE
FSCSKGYLLI GSATSRCEVQ GKGVDWSDSL PECVKIVCHR PQILKGYLAP GFRQFYAYRD
ALEIRCKKGF ILRGSSVIHC EANGEWFPSI PTCEPNGCTN IPDISYASWE GYKFPLRNFE
VFEIGAKLKY QCKPGYRASL NDPQTVTCQE NLTWSSTNGC ERICCPTPDM EKIKIVSERR
DFTGTCIYAY GDYVFYICNE GSYPMSTDGR SSCQADGKWD PAIPSCQADS GLQNRLALFT
FPNISETNVT NKTYLFGHEE NSTEHAMKGV CLKPMVINGN LSVERVIYAE LENITIQCDP
GYTIVGSPNI ICSNRTWYPE VPSCQMEVLE DCRIVSRGAQ LLHCLSSPED VHRALKVYKL
FLEIERLEHQ KEKWIQLHRK PQSMKINRSF RLCN
//
