ID E9QAQ0_MOUSE Unreviewed; 1299 AA.
AC E9QAQ0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Immunoglobulin superfamily, DCC subclass, member 4 {ECO:0000313|Ensembl:ENSMUSP00000076878.7};
GN Name=Igdcc4 {ECO:0000313|Ensembl:ENSMUSP00000076878.7,
GN ECO:0000313|MGI:MGI:1858497};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000076878.7, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000076878.7, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000076878.7,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000076878.7}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000076878.7};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR MaxQB; E9QAQ0; -.
DR PeptideAtlas; E9QAQ0; -.
DR ProteomicsDB; 353283; -.
DR Antibodypedia; 2317; 67 antibodies from 13 providers.
DR Ensembl; ENSMUST00000077696.13; ENSMUSP00000076878.7; ENSMUSG00000032816.16.
DR AGR; MGI:1858497; -.
DR MGI; MGI:1858497; Igdcc4.
DR VEuPathDB; HostDB:ENSMUSG00000032816; -.
DR GeneTree; ENSGT00940000159637; -.
DR PhylomeDB; E9QAQ0; -.
DR TreeFam; TF321506; -.
DR ChiTaRS; Igdcc4; mouse.
DR Proteomes; UP000000589; Chromosome 9.
DR Bgee; ENSMUSG00000032816; Expressed in indifferent gonad and 251 other cell types or tissues.
DR ExpressionAtlas; E9QAQ0; baseline and differential.
DR CDD; cd00063; FN3; 5.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF39; FI24025P1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 5.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00060; FN3; 5.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50853; FN3; 5.
DR PROSITE; PS50835; IG_LIKE; 3.
PE 1: Evidence at protein level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Proteomics identification {ECO:0007829|MaxQB:E9QAQ0,
KW ECO:0007829|PeptideAtlas:E9QAQ0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1299
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003244551"
FT DOMAIN 27..136
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 142..228
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 241..467
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 477..571
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 573..669
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 678..789
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 798..891
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 896..991
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 379..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1299 AA; 139425 MW; 669A95D1ACA07C93 CRC64;
MARADTGRGL LVLTFCLLSA RGELPLPQET TVKLSCDEGP LQVILGPEQA VVLDCTLGAT
AAGPPTRVTW SKDGDTVLEH ENLHLLPNGS LWLSSPLEQE DSDDEEALRI WKVTEGSYSC
LAHSPLGVVA SQVAVVKLAT LEDFSLHPES QIVEENGTAR FECHTKGLPA PIITWEKDQV
TVPEESRLIT LPNGVLQILD VQDSDAGSYR CVATNSARQR FSQEASLTVA LRGSLEATRG
QDVVIVAAPE NTTVVSGQSV VMECVASADP TPFVSWVRQG EDQSKKEGIQ TSGCDAALQG
CSGNLVVGEG VETVPASPSS LLLLCHQMES LSPRMSSFWA GPIYSSPARS LGTLESMSAE
PTSPARVISP LRLLSSECLL PQPSRRRPRR SRGRGPAPRA SCAGRPGSHG PRCTGCTTGS
RCDPMRVKVQ GGGGSLVITQ IGLQDAGYYQ CVAENSAGTA CAAAPLAVVV REGLPSAPTR
VTATPLSSSS VLVAWERPEL HSEQIIGFSL HYQKARGVDN VEYQFAVNND TTELQVRDLE
PNTDYEFYVV AYSQLGASRT SSPALVHTLD DVPSAAPQLT LSSPNPSDIR VAWLPLPSSL
SNGQVLKYKI EYGLGKEDQV FSTEVPGNET QLTLNSLQPN KVYRVRISAG TGAGYGVPSQ
WMQHRTPGVH NQSHVPFAPA ELKVRAKMES LVVSWQPPPH PTQISGYKLY WREVGTEEEA
DGDRPPGGRG DQAWDVGPVR LKKKVKQYEL TQLVPGRLYE VKLVAFNKHE DGYAAVWKGK
TEKAPTPDLP IQRGPPLPPA HVHAESNSST SIWLRWKKPD FTTVKIVNYT VRFGPWGLRN
ASLVTYYTSS GEDILIGGLK PFTKYEFAVQ SHGVDMDGPF GSVVERSTLP DRPSTPPSDL
RLSPLTPSTV RLHWCPPTEP NGEIVEYLIL YSNNHTQPEH QWTLLTTEGN IFSAEVHGLE
SDTRYFFKMG ARTEVGPGPF SRLQDVITLQ KTFSDSLDVH AVTGIIVGVC LGLLCLLACM
CAGLRRSSHR EALPGLSSSG TPGNPALYTR ARLGPPSVPA AHELESLVHP RPQDWSPPPS
DVEDKAEVHS LMGGSVSDCR GHSKRKISWA QAGGPNWAGS WAGCELPQGS GPRPALTRAL
LPPAGTGQTL LLQALVYDAI KSNGRKKPSP ACRNQVEAEV IVHSDFGASK GCPDLHLQDL
EPEEPLTAET LPSTSGAVDL SQGADWLGRE LGGCQPTTSG PERLTCLPEA ASASCSCSDL
QPSTAIEEAP GKSCQPKALC PLTVSPSLPR APVSSAQVP
//
