ID E9T626_RHOHA Unreviewed; 8934 AA.
AC E9T626;
DT 31-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 31-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 62.
DE SubName: Full=AMP-binding enzyme {ECO:0000313|EMBL:EGD22013.1};
GN ORFNames=HMPREF0724_14232 {ECO:0000313|EMBL:EGD22013.1};
OS Prescottella equi ATCC 33707.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Prescottella.
OX NCBI_TaxID=525370 {ECO:0000313|EMBL:EGD22013.1, ECO:0000313|Proteomes:UP000004245};
RN [1] {ECO:0000313|EMBL:EGD22013.1, ECO:0000313|Proteomes:UP000004245}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33707 {ECO:0000313|EMBL:EGD22013.1,
RC ECO:0000313|Proteomes:UP000004245};
RA Muzny D., Qin X., Buhay C., Dugan-Rocha S., Ding Y., Chen G., Hawes A.,
RA Holder M., Jhangiani S., Johnson A., Khan Z., Li Z., Liu W., Liu X.,
RA Perez L., Shen H., Wang Q., Watt J., Xi L., Xin Y., Zhou J., Deng J.,
RA Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L., Villasana D., Johnson A.,
RA Liu J., Liyanage D., Lorensuhewa L., Robinson T., Song A., Song B.-B.,
RA Dinh H., Thornton R., Coyle M., Francisco L., Jackson L., Javaid M.,
RA Korchina V., Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N.,
RA Okwuonu G., Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W.,
RA Jakkamsetti A., Pham P., Ruth R., San Lucas F., Warren J., Zhang J.,
RA Zhao Z., Zhou C., Zhu D., Lee S., Bess C., Blankenburg K., Forbes L.,
RA Fu Q., Gubbala S., Hirani K., Jayaseelan J.C., Lara F., Munidasa M.,
RA Palculict T., Patil S., Pu L.-L., Saada N., Tang L., Weissenberger G.,
RA Zhu Y., Hemphill L., Shang Y., Youmans B., Ayvaz T., Ross M.,
RA Santibanez J., Aqrawi P., Gross S., Joshi V., Fowler G., Nazareth L.,
RA Reid J., Worley K., Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGD22013.1}.
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DR EMBL; ADNW02000024; EGD22013.1; -; Genomic_DNA.
DR RefSeq; WP_005513159.1; NZ_CM001149.1.
DR STRING; 43767.A6I91_15095; -.
DR HOGENOM; CLU_222728_0_0_11; -.
DR OrthoDB; 5475787at2; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000004245; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd17646; A_NRPS_AB3403-like; 1.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR CDD; cd19543; DCL_NRPS; 2.
DR CDD; cd19540; LCL_NRPS-like; 4.
DR Gene3D; 3.30.300.30; -; 7.
DR Gene3D; 3.40.50.980; -; 12.
DR Gene3D; 1.10.1200.10; ACP-like; 6.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 9.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 10.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR001031; Thioesterase.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 7.
DR NCBIfam; TIGR01720; NRPS-para261; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 7.
DR Pfam; PF13193; AMP-binding_C; 7.
DR Pfam; PF00668; Condensation; 10.
DR Pfam; PF00550; PP-binding; 7.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00823; PKS_PP; 7.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 7.
DR SUPFAM; SSF47336; ACP-like; 7.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 19.
DR PROSITE; PS00455; AMP_BINDING; 7.
DR PROSITE; PS50075; CARRIER; 7.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 6.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000004245}.
FT DOMAIN 1245..1320
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2316..2391
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3372..3446
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4906..4981
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5988..6062
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 7525..7600
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 8586..8661
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1541..1560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8934 AA; 960153 MW; 13EADDFB22BDB34E CRC64;
MTMSGSREPV GHGSGTPALP AEAFPLSAVQ RSMWFAQQLT PAVPIFIAQY VTLQGDLDVD
LLSRCAVTAA EEFQSPFLHL IDVDGEPYQF IDPDTDTSIE QVDLRDHPDP TAAAHAWMEH
DYSVPIDLTR DRLIDMTILQ VGDREYLWYT RIHHVALDGY SGMTVANRIA ALYTAALEHR
DPEPNRALDL RELLAIDQKY RASGRFQADR EYWADHIAGI EAGSTLAETD APVSAVSRLE
SAPLPEAVIT ALDSTDRTLE ATPAAVLIAA FACYLARMTG RTDVLVNMPV SARTTAPLQR
SGGMLVNVAP LRATVLPNDT VADLVGRIQL ELMGALRHQR CSIEDIRRDA GLTGTARGLA
GPMVNVMLFH QKMTLGDIEG EYHIVTSGPV EDLLVNFFQS GSPTRTFVEF RANPGRYSQE
ALHTHHRRFL ELVEEFVQAS ADTRVADIHA ESSVVGAQLL RTAAQLEFWS RELAGLPDIL
SLPSDRPRPA RRALASDRVD FEIPAAVHRA VVAQSEARGC TVFAAVHAAL VVLLARLADV
DDVAIGTPVT GRSPAGEFVN TLTLRTRLSP GLTFDDLLTD VCRADTAAFR HAETPFAQLV
ESLDRTRENA HSPLFQVMLE FHDGRTPHLD EDGLVVRGVD TGPDISALDL RLTVEERFAG
NAAGDAVPDG VHASFAFATD MFDPETIETL SARFLRVLDA VLEDPSTVVA DIDLLSEEER
RQLSGVWGGD GVEPRTLAEI LAAAAHTDPT RTALTYEGRQ LSYRALDEDS NRLARLLVSR
GVGPESVVAL SMPRSIESVA SVWAVAKTGA AFVPVDPNYP ADRIEHMLTD SGATLALTVA
AHAAAVADIV PALVVDDPGF GAQVHQWSPD SITDADRSAP VRIDNPAYLI YTSGSTGTPK
GVTVTHRGLA NFAEDERRRY GVRPDSRTLH FSSPSFDASV LELMLAFGAG ATMVIAPPTV
YGGAELTALL RDERVTHAFV TPAALGSVDA DALPELECVV TGGEACPPYL VEQWAPRHRM
FNAYGPTEAT VVSSVSDPLV VGQDVTIGCP PIGTGVLVLD ARLRPVPPGV AGELYVYGEG
QARGYHARAG TTAERFVANP FDGTRMYRTG DLVRWRRFGR RHSLEYVGRT DFQIKIRGYR
IELGEVEAAL RSHPDVGFAL ATGFVGPSGD TLLVAYVQAE SNRETGVGEH LASEVTAHAA
DVLPPHMVPA SVVVLDSLPL TPAGKLDRRA LPEPRFDVGT GEFHAPATLD EKKIAGVFSE
LLGVERIGTT DSFFDLGGNS LTATRIVARI NATLGTELSV LDLFEAPTVG ALAARVEAAG
PGHGARPPLV PRDHTGPVPV SLAQQRMWFV NQLAPGSAAY NIPIAVRLSG PLDVAALRGA
LADVVERHQT LRTVFPNTSD GPVQQVRSVA DAALDLEPED VTETQLPQRL QGVATAPFDV
SVQLPVRAHL WRLGPTEHVL ALVAHHVAAD GLSMAPLARD VMVAYGARAA GTEPAWPPLA
VQYADYAVWQ RELLGAEDDP RSLAARQIAF WRDELTGAPD LLELPTDRPR PPQQSMRGGT
VSCTIAPHLH RRLLEVAGEY EASLFMVLHA ALAVLLARAS GATDVTIGSP VSGRGEAELD
DLVGMFVNTL VLRSRVDHGG TFSDLLAHTR TTDLAALGNT DVPFERLVEV LDPPRSEAYS
PLFQVMLVLQ GSERNRLELP GLAVEVDEID TGTAKFDLQV ILTEQSDEEG RPGPIEATLS
YATDLFDPDT VAALAERYLR ILEAVSVDPA VRVGDIDVLV DGERELVLDE WNATAHSVPD
ATLTDLFDAQ ARRTPHAVAL TFGDEQLTYA EFASRARRLA RELIARGVGP ESRVALSMRR
SFDLLIGMYA VTEAGGAYVP LDPDHPAART EYVLASAAPA CVLTTRRDRA GLQTDIDVLE
IDSLDLAGRG DGPIRPEERV GALRPDHVAY VIYTSGSTGR PKGVAVSHRA IVNRLAWMQD
RYHLTGTDVV VQKTPATFDV SVWEFFWPLQ NGASLAIALP EGHRDPAYLS QLIHDRGVTV
AHFVPSMLAA FVVGADPVQC RSLRTVFCSG EGLPPSTAEA FAEFVGPAGA ELHNLYGPTE
AAVDVTYRQY TAADTVSVPI GTPVWNTQVY VLDARLHPAP VGVPGELYLA GVQLARGYVG
RPDLTAERFV ANPFGAPGTR LYRTGDLVRW RKTGHLDYSL DYLGRTDFQV KLRGLRIELG
EVEATLLSRP GVAQAVVVVR RDELVGEALV GYVIADPGVE LEPAALRESL AESLPAYMVP
SQILVLDEFP LGSTGKLDRR ALPAPEFGSV EAEFVAPRGP VEEILALIFG ELVGTTRIGV
YDSFFDLGGN SLTATRLVAR VNDALDAHIG VRDVFDAPTV AALALRIESG GMRGPERAPL
EPAERPAAVP VSLAQKRMWF INQFDTSSAA YNVVLPVRLD GDLDRGALRA AVADVLDRHE
SLRTRFPMID GEPVQVIVPT AAVAPDLEPE SVAEQDVAER VAEFAGRGFD VTVAPPVRSL
LLRVGPQTHV LVIVVHHICA DGFSLAPLAR DVMSAYIART EDRAPHWTPL AVQYADYALW
QQKVLGGTDD PDSVLSRQLE YWARTLDGLP EVLDLPTDRP RPSERTLRGA VHGFRLGPDV
HRRLTAVART HNATVFMAVH AALAALLARL GDTDDVAIGT PIAGRGAAAL DDMVGMFVNT
LVLRSHFDPA ATYSELLAAV RDGDLDAFHN ADLPFERLVD ALAPERSTAH SPLFQVMLEF
RNNEQPRLEL PGLTVTLVDT GTDSTNFDLQ LTLTEEFTES GEPAGVAAGF TYATDLFDPA
TVTRLAERFG AVLRAVTADP AVRVGDVDLL TADERAAIAP VSGGAGVPAR TLPELLATAG
VVDPDATAVV FEGRELSYRQ LDADSDRLAR LLIARGLGPE SVVALALARS LESVTATWAV
AKTGAAFVPV DPNYPADRIE HMLTDSGAVV GLTVHGHRDA LPPVTEWLVL DDSAVRDRMQ
RQPGGPVTDA DRVRPVRLDD PAYLIYTSGS TGIPKGVVVS HRGLANFAAE ERTRFGITPR
SRTLHFSSPS FDASILELLL AVGSGATMVV APPTVLGGDE LRDLLRENRV THAFVTPAAL
ASVDPAGLTA LECVATGGEA CPPELVAQWA PGRRMFNAYG PTEATVVASI SEPLAVGVPV
TIGRPPLGTS LVVLDARLHP VPAGVPGELY VLGSGLARGY HARPGTTGER FVANPFGDPG
SRMYRTGDLV RWNGSGQLEY LGRTDFQVKV RGFRIELGEI ESALRRFPGV ARAVVTVDGS
GPASRLVGYV VPEAGAAVDP ADVTEFVGTF LASYMVPSAV MVLDALPLGP AGKLDRRALP
APDFGARTAG RAPRSERERQ LADLFAEVLG LDSVGVDDSF FGLGGDSIMS IQLVSRAKSA
GLHFTPRDVF EHKTVEALAR VAQSGADTAT LAELDGGGVG DVPLLPVAHW LLDRGGHHDR
FSQAALLTAP EGLDDASLTG AVQAVLDRHD MLRARIRPGE HRMIVPPAGS VYAEWLIRRI
RVDAAPGTDA FADTVRAELD AAEDRLDPSA GEMMQVVWLE SASGGGRLLI VVHHLVVDGV
SWRILVPDLA TAWAQIVAGE RPDPAPVGTS MRRWAHGLVD AAADRRDELE LWRAMLSGDD
PLLGARPLDP AVDVASTART VTVEVSPDVT DALLTTVPDA FRGSVNDGLL TALAMALVRW
RRDHGVDADT ALVTLEGHGR EDHVLPGADL ARTVGWFTTL FPIRLDLTGI DIDDAFTGGR
GAGAAVKAVK EQLLAVPDHG IGYGMLRYLD DEGGRALRGL ASAQVSFNYL GRLTAAVPED
QRAAGWVPTD DADLSVLQDA DLPVASVLDI NAVTTDGADG SRLRATWGFP AGVLTAADVT
ELAGLWTEAL IALARHVSRP GAGGLSPSDL DLVDLGQPEI ETLEQRFPNL ADVWSLSPLQ
SGLLFHAQLA DRSVDAYLVQ MMLDVRGADP GRLRRAGQAM LDRHPNLRSA FVHGPDGTPV
QVVQERVPLP WNEIDLSEHD EPVREAELAR LIADDRTRRF DMAEAPLIRF LLVRTGPDEH
RLILTNHHIL LDGWSTPLMM QELLTLYATD GDTTVLPRVH AYRDYLAWIA AQDPEAGVRA
WTRSLAGLDE PTLLAPLDRG REQATVPAEI DISLDVTRTA RLQSIGRQWG VTLNTMVQAA
WAIVLGASTG RDDVVFGGTV SGRPPHIPGI ESMIGLFINT LPVRVRLDAR ESVGELLRRI
QSEQAGLLDH HHVSLTDIQD AVGPALAFDT LTVFESYPVD RSAITDADIS GLRLVRVHEG
SDAAHYPLTL VANADDRLRM KLKFLPDLFD RGQARSLAER VQRVLVEMSE DPQCPLARLR
LLSDAEWAEL VPLRGRPGRS VRTLPQLFTD AAAADPDAIA LVAGTTEVTY RELDERSNRL
ARVLLDDGVG PESFVALGIP RSIDSVVAVW AVAKTGAAFL PVDPNYPAER IAFMLEDSGA
TAGLTVTGAR DRLPATVPWT VLDDPAFESR RAAQSAAPVG DDERPVPLRL THPAYVIYTS
GTTGTPKGVV VTHEGLDNLS EEYLTHFATR PSSRTLHFST PSFDAAVLDY LLAFGPAATM
VIAPTSVYGG SELADLIRDQ HVTHAFITTA AAATVDPAGL DEFTEVMVGG EAVPPELVAR
WAHGRRFYNG YGPTEATVMA NVSAPLVTGE TVTIGAPLRG VSELVLDTNL RPVPAGVPGE
LYIAGPNLAR GYHRRPGLTA ERFVANPHGV PGERMYRTGD VVRVLADRTI EYVGRSDFQV
KIRGFRIELG DIDNAFGDHP DIRFAVTLGR PGPTGETSLV TYVLPVAGAQ PEPGALREYV
AEHLPAQMVP ASIMILDEIP LTPIGKLDRA ALPAPEFLPA ATTFRAPTDP TEQTIVDTFT
AVLGLERIGV DDSFFDLGGN SLIATRVIAR LGAALGVDLG VRALFEAPTA HELARWVSRA
HLDAAARPQL RPQDRPDPLP LSLAQKRMWF INQFDTESAA YNIPLAVRLT GDLDVAALTA
AVADVQERHE TLRTLFPSRD GEPVQLVVPA AEAAPSLDAV DVPPDRVPER IAALISRGFD
VTTAVPVRAE LLRLGPREHV LTIVVHHICA DGFSMAPLAR DVMAAYVART GGHVPQWAPL
PVQYADFALW QHQVLGSEDD PDSPGRRQLA FWTEALAGLP EAITLPTDRP RPSRQSFDGA
RVEFEIPAEV HRALAESARR HGATMFMATH AALAVLLAKL SGTDDIAIGT PIAGRGEAEL
DDLVGMFVNT LVLRSDVDPA GGFADLLART REFDLAAFGH ADLPFERLVD VLAPERSTAH
SPLFQVMLEF QNNELPRLEL PGLVADPVAA DLAVAKFDLQ LTLAERHDDA GVPDGIAAVF
TYATDLFDPG TVRELGERFT RLLDALVAEP ERAIGDITIT TATELDTMLH RWNAEGARAA
DETLADRFAL AAARFPDRPA LTYEASTLGY AELDARANRL ARHLVSLGVG PETLVAVALP
RSADLVVALL AVIKSGAGYL PLDVTYPAER LSYMLTDAAP VCVLTTGADA NAIPSTDVPL
IRLDTDETAA ALAAAPDRAV TDADRLTPLR PDDVAYVIYT SGSTGRPKGV QVTHRNVLTL
FANTTGAFGF DEHDVWTMFH SYAFDFSVWE LWGPLLHGGR LVVVDFYTAR SPEMFLDLLR
TEQVTVLNQT PTAFYQLAEA DRLASEQGTT ATDLALRYVV FGGEALDLGQ LGRWYTRHPD
SAPRLVNMYG ITETTVHVTH LELDRAFAEA ADASVIGRAI PGLRVVVLDE RLHSVPPGVV
GEMYVAGEQL TRGYLGRSAL TSSRFVADPF GAPGSRMYRT GDLARWNRDG RLEYLGRSDF
QVKIRGFRIE LGEIEAALLR YPGVAQAVVA VHRDGTGPAR LVGYAVPEQG LDVDPQDVLG
HVGRELTSYM VPATLMLLDE LPLTANGKLD RKALPQPEFG TGAARGRAPE TDVERTLAGL
FAEVLGLDSV GVDDSFFGLG GDSIMSIQLV SRAKDAGLRF TPRDVFEHRS VAGLAAVAAA
DSGETPVHLD ELPGGGVGEF PLTPIMHWLL ERSDDVRRYT QTALLALPSG TDRDRLARTL
QAVVDRHDML RAQLHTGPDP HMLVRPVGAV DADDLITRIP VDALSGPDFT AVAGAALDDA
AGRLDPAAGA VLQAVWFDAG ETGGRLLLVI HHLAVDGVSW RILVPDLAAA WTRIAAGELP
DLAPTGTSMR RWAHGLADAT AGRDRELELW QGTLDTPDPV IGSRPLDPAV DVYGTVDKVS
VELPSAVTEA LLTTVPEVFR GNVNDALLTA LAMALTRWRR TRGADTDAAL VNLEGHGRED
QVVPGADLGR TVGWFTTIFP VRLDLTGIDV DDAFAAGPAA GAALKAVKEQ LLAIPDHGIG
FGMLRYLDPR TGPVLAELPV PQVGFNYLGR LGGTSTGTDV PWVPVSDTEL DDAPSATMPV
ASALDVNAVV GDTPDGPRLR ATWAFPSGVL AAVDVGELAD LWVRALSALA RHAAHPGAGG
LTPSDLDLVR LDQDAIEALE HRYPGLDDVW SLSPLQAGLH FHAMLADDSV DAYLVQLTLS
LGGTVDTDRL WRAGQALLDR HPNLRAAFVR VEGAASDSGA VQVIPDRVEL PWTEVDLSRL
DPGTRARRFD ELIAADRGTR FDLTAAPAIR MTLVKFGAGD YRLVVTNHHI LLDGWSTPLV
IRDLLTLYAT DADASVLPRV HPYRDYLAWM ATQDPAESTD AWRKALAGLE EPTLLAPAVP
RAGGGTAELE VALTAEHTDT LRSLVRERGL TLNTVVQAAW GIVLGALTAR TDVLFGGTVS
GRPPQIPGIE SMVGLFINTL PVRVTLDAGE TLGELLDRVQ REQAALLDHH YLGLADIQRA
TGPAATFDTL TVFESYPVDR NALTADTDIA GLKVTGIDGR DAAHYPLSLV ASVNGSLNLK
FEYFPEVFDP DVVESIATRV TVVLEHIATD PDRPLARLDL LTDTERHDLA PVEGPVGGSI
RTLPDIFTDA AALDPDAIAL SFSGREVTYR ELDTRSSRIA RVLIDQGVGP ESYVALGIPR
SVESVLAVWA VTKTGAAFVP IDPNYPPERI EHMLADSGAG LGLTVAAHRH RLPDTATWLT
LEDPDVAAAC AAHSDAPVTD TDRTAPLGLE HAAYVVYTSG STGRPKGVVV AHRGLDNFAL
DQQARFGATA TSRTLHFATP SFDGAVFEYL QAFGVGATMV IAEPTVFGGA DLARVLADGH
VTHAFVTTAA LATVDPTGLD EFTHVAVGGE ACPPELVARW APGRDLHNAY GPTETTIMSN
ISAPMTVGEQ ITIGGPIRGV HEVVLDGRLQ PVPVGVPGEL YIAGLGLARG YHRRPGLSAE
RFVANPFGKP GERMYRTGDI VRWRPDLTIE YVGRSDFQVK VRGFRIELGE IDAALAADPT
VGFAVTLGVP GPAGDTVLAS YVVATTGATV ETGALLDRLS EQLPSHMVPA AVTVLDEIPL
TPVGKLDRAA LPEPEFAFTS GEFRAPTNPL EYTLSDVFTE VLGVDRIGID DSFFDLGGNS
LIATRVTARL SGLLDADIPV RALFEAPTIH ALAQWVARER GAGTGHTRPE LGRRERPDRI
PLSLAQQRMW FINQFDTASA AYNIPMAVNL TGALDTGALR DAVGDVLERH ESLRTAYPIV
DQEPTQEVWP VGDVLTDLTP VPVDDDAELR RQITAFASHG FDVTAAPPVR AELLEIDDEH
HVLVIVVHHI CADGYSMAPL GRDLMAAYTA RAAGTSPQWA PLPVQYADYT LWQHEMLGTD
TDPDSLISRQ LRFWTEELAG LPDVIQLPTD RPRPVQQTFR GGRVEFRVPA ELHTRITELA
HRHGASMFMA MHAALATVLA RLADTDDIAI GTPIAGRGEM ALDELVGMFV NTLVLRTRID
HDTSFDALLQ QVRESDLAAF GHAEVPFERL VEEINPPRST SYSPLFQVSI EFQNNERPRL
ELPGLTVEGV GIDAQVAKED LELVLAEEFT DTGDPAGVLA SLDFATDLFD ESTVRGIAHR
FIRVLEAVVA DPARAVGDIE ILDSGELAAL APAHGGSDVS PHVWPELLES AAAVDPDAVA
LSYLGRTLTY RQLDERSNRL ARVLAGRGVG PETFVALGMP RSIDEIVSIW AVAKSGAAFV
PVDPNYPAER IAHMLTDSGT RLGLTTSALR ERLPDTVPWL VLDDDAIAAR LADASPAPVT
DADRTAPLHL THPAYLIYTS GSTGRPKGVI VTHLGIANLT EEERQRFSVT PDARVSHLAS
PSFDASVFEM MMAFSAGARL VIVPPTVYGG AELTDLLSRE GVTHGFITPT ALASIEDEGL
ESLRILAVAG EACPPELVAK WAPGRRMFNG YGPTETTIQA SVSAPMQPGE TVNIGGPAIG
FEEAVLDGRL RPVPVGVPGE LYISGPGLAR GYHNRPGLTA ERFVANPFGP PGSRMYRTGD
VVRWRHDDTI EYIGRSDFQV KVRGFRIELG EIDAVLTRHP AITFAATLGH TGPSGDTLLA
SYVRPVEGHS VEARELRAHV AAQLPAHMVP SAVVVLDEIP LTPVGKLDRR ALPTPEFTSL
TTEFRPPSTA TERAVTEVFA DVLGVDHVGI DDSFFDLGGN SIIATRIMSE LQARLGRQLP
LQTMFLDPTP SGLAKRIDLP VGYLGRSDSP VDDALGVVIP LRSNGERPPL FCIHPGIGLS
WGYAGLVQYL AKDRPAFGLQ LPLLSGGPDF GSVQQLAHRY VEEIRTVQPH GPYHLLGWSL
GGVIAHAMAV ELRGAGEEVA TLAIMDSYLT EAEEEPGHLT VVELLEGLGL DLAPYGDVRD
LTYAQAVDLL NESLGQDTGL TPAHLERINE GFTTSARIMN RYAPDVFDGD LLFFTAGRGD
GSAQSTPRHS PQVWQPAITG RIREFTIDCE HNQMIEPEAL SAIGPLLEEY LASH
//
