ID ELOF1_BOVIN Reviewed; 83 AA.
AC A4IFR3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2007, sequence version 1.
DT 24-JAN-2024, entry version 91.
DE RecName: Full=Transcription elongation factor 1 homolog;
GN Name=ELOF1;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Fetal spinal cord;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ELOF1 family. {ECO:0000305}.
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DR EMBL; BC134722; AAI34723.1; -; mRNA.
DR RefSeq; NP_001098978.1; NM_001105508.2.
DR RefSeq; XP_015327474.1; XM_015471988.1.
DR RefSeq; XP_015327475.1; XM_015471989.1.
DR AlphaFoldDB; A4IFR3; -.
DR SMR; A4IFR3; -.
DR STRING; 9913.ENSBTAP00000052837; -.
DR PaxDb; 9913-ENSBTAP00000052837; -.
DR Ensembl; ENSBTAT00000052334.3; ENSBTAP00000052837.2; ENSBTAG00000038151.3.
DR GeneID; 100125945; -.
DR KEGG; bta:100125945; -.
DR CTD; 84337; -.
DR VEuPathDB; HostDB:ENSBTAG00000038151; -.
DR VGNC; VGNC:28446; ELOF1.
DR eggNOG; KOG3214; Eukaryota.
DR GeneTree; ENSGT00390000000053; -.
DR HOGENOM; CLU_105983_2_0_1; -.
DR InParanoid; A4IFR3; -.
DR OMA; CLDANKK; -.
DR OrthoDB; 276470at2759; -.
DR TreeFam; TF313731; -.
DR Proteomes; UP000009136; Chromosome 7.
DR Bgee; ENSBTAG00000038151; Expressed in myometrium and 108 other cell types or tissues.
DR GO; GO:0008023; C:transcription elongation factor complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000993; F:RNA polymerase II complex binding; IBA:GO_Central.
DR GO; GO:0006368; P:transcription elongation by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934:SF0; TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR20934; UNCHARACTERIZED; 1.
DR Pfam; PF05129; Elf1; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 3: Inferred from homology;
KW Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..83
FT /note="Transcription elongation factor 1 homolog"
FT /id="PRO_0000327210"
FT BINDING 26
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 29
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 50
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
FT BINDING 53
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:P60003"
SQ SEQUENCE 83 AA; 9462 MW; 77F11EFBEC72AC6F CRC64;
MGRRKSKRKP PPKKKMTGTL ETQFTCPFCN HEKSCDVKMD RARNTGVISC TVCLEEFQTP
ITYLSEPVDV YSDWIDACEA ANQ
//
