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Database: UniProt
Entry: ETFD_ACIAD
LinkDB: ETFD_ACIAD
Original site: ETFD_ACIAD 
ID   ETFD_ACIAD              Reviewed;         570 AA.
AC   P94132;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-JUL-2019, entry version 120.
DE   RecName: Full=Probable electron transfer flavoprotein-ubiquinone oxidoreductase;
DE            Short=ETF-QO;
DE            Short=ETF-ubiquinone oxidoreductase;
DE            EC=1.5.5.1;
DE   AltName: Full=Electron-transferring-flavoprotein dehydrogenase;
DE            Short=ETF dehydrogenase;
GN   Name=etfD; OrderedLocusNames=ACIAD1680;
OS   Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Acinetobacter.
OX   NCBI_TaxID=62977;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9294455; DOI=10.1128/jb.179.18.5935-5942.1997;
RA   Williams P.A., Shaw L.E.;
RT   "mucK, a gene in Acinetobacter calcoaceticus ADP1 (BD413), encodes the
RT   ability to grow on exogenous cis,cis-muconate as the sole carbon
RT   source.";
RL   J. Bacteriol. 179:5935-5942(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33305 / BD413 / ADP1;
RX   PubMed=15514110; DOI=10.1093/nar/gkh910;
RA   Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S.,
RA   Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P.,
RA   Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT   "Unique features revealed by the genome sequence of Acinetobacter sp.
RT   ADP1, a versatile and naturally transformation competent bacterium.";
RL   Nucleic Acids Res. 32:5766-5779(2004).
CC   -!- FUNCTION: Accepts electrons from ETF and reduces ubiquinone.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ubiquinone + reduced [electron-transfer flavoprotein] =
CC         a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein];
CC         Xref=Rhea:RHEA:24052, Rhea:RHEA-COMP:9565, Rhea:RHEA-COMP:9566,
CC         Rhea:RHEA-COMP:10685, Rhea:RHEA-COMP:10686, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16389, ChEBI:CHEBI:17976, ChEBI:CHEBI:57692,
CC         ChEBI:CHEBI:58307; EC=1.5.5.1;
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC       Note=Binds 1 [4Fe-4S] cluster.;
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
DR   EMBL; U87258; AAC27118.1; -; Genomic_DNA.
DR   EMBL; CR543861; CAG68525.1; -; Genomic_DNA.
DR   RefSeq; WP_004926550.1; NC_005966.1.
DR   SMR; P94132; -.
DR   STRING; 62977.ACIAD1680; -.
DR   EnsemblBacteria; CAG68525; CAG68525; ACIAD1680.
DR   KEGG; aci:ACIAD1680; -.
DR   eggNOG; ENOG4105DWH; Bacteria.
DR   eggNOG; COG0644; LUCA.
DR   HOGENOM; HOG000259450; -.
DR   KO; K00311; -.
DR   OMA; ENCIQCR; -.
DR   OrthoDB; 1770293at2; -.
DR   BioCyc; ASP62977:ACIAD_RS07745-MONOMER; -.
DR   Proteomes; UP000000430; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0004174; F:electron-transferring-flavoprotein dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR040156; ETF-QO.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10617; PTHR10617; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   4Fe-4S; Complete proteome; Electron transport; FAD; Flavoprotein;
KW   Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Reference proteome;
KW   Transport; Ubiquinone.
FT   CHAIN         1    570       Probable electron transfer flavoprotein-
FT                                ubiquinone oxidoreductase.
FT                                /FTId=PRO_0000200681.
FT   DOMAIN      530    559       4Fe-4S ferredoxin-type.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00711}.
FT   NP_BIND      13     27       FAD. {ECO:0000255}.
FT   METAL       515    515       Iron-sulfur (4Fe-4S). {ECO:0000255}.
FT   METAL       539    539       Iron-sulfur (4Fe-4S). {ECO:0000255}.
FT   METAL       542    542       Iron-sulfur (4Fe-4S). {ECO:0000255}.
FT   METAL       545    545       Iron-sulfur (4Fe-4S). {ECO:0000255}.
SQ   SEQUENCE   570 AA;  62996 MW;  0107DD88E78A7DE5 CRC64;
     MITIEREAME FDVVIVGAGP AGLSAAIKIR QLAIENNLPD LSVCVVEKGS EVGAHILSGA
     VLEPRAINEL FPNWKEEGAP LNVPVTEDKT YFLMSDEKSQ EAPHWMVPKT MHNDGNYVIS
     LGNVVRWLGQ KAEELEVSIF PGFAAAEILY HADGTVKGIQ TGDMGIGKDG EPTHNFAPGY
     ELHAKYTLFA EGCRGHLGKR LINKFNLDQD ADPQHYGIGI KELWEIDPAK HKPGLVMHGS
     GWPLSETGSS GGWWLYHAEN NQVTLGMIVD LSYENPHMFP FMEMQRWKTH PLIKQYLEGG
     KRISYGARAV VKGGLNSLPK LTFPGGCLIG DDAGFLNFAK IKGSHTAMKS GMLCGEAVFE
     AIARGVDKGG DLAIARVVEG EDLFDKELTT YTQKFDKSWL KEELHRSRNF GPAMHKFGLW
     IGGAFNFVDQ NIFKVPFTLH DLQPDYSALK TQDQATFKPN YPKPDGKLTF DRLSSVFVSN
     TVHEENQPSH LKLTDASIPV AVNLPRWDEP AQRYCPAGVY EIVDEGEGNK RFQINAANCV
     HCKTCDIKDP SQNITWVTPE GGGGPNYPNM
//
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