ID EXO70_EMENI Reviewed; 631 AA.
AC Q5AZS0; C8V1U3;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 24-JAN-2024, entry version 92.
DE RecName: Full=Exocyst complex protein exo70;
GN Name=exo70; ORFNames=AN6210;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Involved in the secretory pathway as part of the exocyst
CC complex which tethers secretory vesicles to the sites of exocytosis.
CC Also plays a role in the assembly of the exocyst (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Bud {ECO:0000250}. Bud neck {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the EXO70 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACD01000105; EAA57996.1; -; Genomic_DNA.
DR EMBL; BN001301; CBF69955.1; -; Genomic_DNA.
DR RefSeq; XP_663814.1; XM_658722.1.
DR AlphaFoldDB; Q5AZS0; -.
DR SMR; Q5AZS0; -.
DR STRING; 227321.Q5AZS0; -.
DR EnsemblFungi; CBF69955; CBF69955; ANIA_06210.
DR GeneID; 2870804; -.
DR KEGG; ani:AN6210.2; -.
DR VEuPathDB; FungiDB:AN6210; -.
DR eggNOG; KOG2344; Eukaryota.
DR HOGENOM; CLU_010236_4_2_1; -.
DR InParanoid; Q5AZS0; -.
DR OMA; GIIRAGP; -.
DR OrthoDB; 460764at2759; -.
DR Proteomes; UP000000560; Chromosome I.
DR GO; GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
DR GO; GO:0000145; C:exocyst; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1280.170; Exocyst complex component Exo70; 1.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR004140; Exo70.
DR InterPro; IPR046364; Exo70_C.
DR PANTHER; PTHR12542:SF41; EXOCYST COMPLEX COMPONENT 7; 1.
DR PANTHER; PTHR12542; EXOCYST COMPLEX PROTEIN EXO70; 1.
DR Pfam; PF03081; Exo70_C; 1.
DR Pfam; PF20669; Exo70_N; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Exocytosis; Protein transport; Reference proteome; Transport.
FT CHAIN 1..631
FT /note="Exocyst complex protein exo70"
FT /id="PRO_0000118969"
SQ SEQUENCE 631 AA; 70207 MW; 850C8ECAEA67EF07 CRC64;
MVAPRDTAFA EESAEVEVLY ANLEKLKRLT KKIQGSLVRL ETGGNVVKHA IGPIYSNTQS
LQITNNNIDR VIEAIERLRQ PLDAKNREEG VIRAGPQPNN LPQYLAAMRG VNDALMDLTS
TNLKSNQKAI SEFTSLLGIG NSKLQDLLRL KLGEHVSPIE PLHYLTKDLP FPTIPEDRIA
EIAPICAAIN SAAVHVPHRG EGGSPALKIY ADVRGPYIST SAQNLAIASL NTLKRRVDDE
SPYKQGTNGI GTYSDALENF IYAEWEAIKR IFTGDHRGLA LQMTCRSAIA EYSKTIRELN
DYIRTNLLTD CFLAFEIIDI VTAKSYDIEL KTGELKSLFL EALRPVRETA KYSLAELLEE
TKRRAQAIPM LPPNGAPTPL VDKVMRSLIE LTGYQKPLAS ILTSLGDGNW RSTSASSMNT
PLDVNPDSDV LFSHFILDVI ETLLIALEAR ARQLHRTKAA QGVFLSNVFC LVDRAIRSSP
ELARFLGSPD SVSRIDTFRK RATSTYLDAW KETSHYLLDV QYTSHTRGGS RPQSGGAVDS
SAIVKSLSSR DKDAIKDKFK AFNASFDDLV ARHKSFYMER EVRSVLAREV QAVLEPLYAR
FYDRYHELDK GRGKYTKYDK GSLSAQLASL Q
//
