ID F0IF49_9FLAO Unreviewed; 946 AA.
AC F0IF49;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:EGD34204.1};
GN ORFNames=HMPREF9071_1139 {ECO:0000313|EMBL:EGD34204.1};
OS Capnocytophaga sp. oral taxon 338 str. F0234.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=888059 {ECO:0000313|EMBL:EGD34204.1, ECO:0000313|Proteomes:UP000003023};
RN [1] {ECO:0000313|EMBL:EGD34204.1, ECO:0000313|Proteomes:UP000003023}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0234 {ECO:0000313|EMBL:EGD34204.1,
RC ECO:0000313|Proteomes:UP000003023};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGD34204.1}.
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DR EMBL; AEXX01000028; EGD34204.1; -; Genomic_DNA.
DR RefSeq; WP_009745585.1; NZ_GL872413.1.
DR AlphaFoldDB; F0IF49; -.
DR STRING; 888059.HMPREF9071_1139; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_0_2_10; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000003023; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Endonuclease {ECO:0000313|EMBL:EGD34204.1};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Hydrolase {ECO:0000313|EMBL:EGD34204.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000313|EMBL:EGD34204.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000003023};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 608..939
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 946 AA; 106420 MW; 017D30C42542CAC3 CRC64;
MKKDKNIIVQ GARVHNLKNI DVQIPRYKLV VVTGLSGSGK SSLVFDTIYA EGQRRYIETF
SAYARQFLGG LERPDVDKID GLSPVIAIEQ KTTSKSPRST VGTITEIYDF LRLLYARASD
AYSYRTGEKM VSYTDSQIQE LILQEYEGKA IHILAPIVQS RKGHYRELFE QIAKQGFLKV
RVDGQIREIE YGMKLDRYKT HDIEVVIDRL EIKNNDITQR RLSESIQTAM RHGNGILMIL
SDKNETPRYF SRNLMCPTTG ISYPLPEPNT FSFNSPKGMC PHCNGLGTIQ EVTLSKLIPD
MSLSIKQGAI TAIGAEKRTW IFQQLETILR KFGHKLSDPV EKLPKEAIDM ILFGGKEKFS
EKSEVMGITR DFSIDFDGIV NFIEQQYQDM ESSASIQRWA KDFMEEKTCP ECGGSRLRKE
ALYFRIADKN IAELSAMSIA ELMQWFDILP EKLSVRQKKI AHEILKEIRE RLRFLLDVGL
DYLSLGRSSK TLSGGEAQRI RLATQIGSKL TNVLYTLDEP SIGLHQRDNE RLINSLKSLR
DIGNSVVVVE HDADMMLHAD YVIDIGPKAG KGGGEVIFAG TPQQMLQTHT LTASYLNGER
AIEVPQERRK GNGYFIELIG CTGNNLKNVS VKFPLGMMIG VTGVSGSGKS TLINETLYPI
LNAHFYNALK KPMPYKQIVG LEYIDKVIDI DQSPIGRIPR SNPVTYTGVF SEIRDLFSHT
PEAMIRGYKP GRFSFNVKGG RCETCEGGGM KVIEMNFLPD VLVECETCHG KRFNRETLEI
RYKGKSIADV LAMTIDEAVA FFEPIPKIYR KLKTIQEVGL GYITLGQPST TLSGGEAQRI
KLATELSKRD TGNTFYILDE PTTGLHFEDI KILMEVLNRL TEKGNTVLII EHNLDVIKMM
DYLIDMGPEG GKGGGQVVAM GTPEEVAKNR KSYTAKFLKE VLKTKR
//
