ID F0KF50_ACICP Unreviewed; 535 AA.
AC F0KF50;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Glucose-methanol-choline oxidoreductase {ECO:0000313|EMBL:ADY81918.1};
GN Name=alkJ {ECO:0000313|EMBL:ADY81918.1};
GN OrderedLocusNames=BDGL_001332 {ECO:0000313|EMBL:ADY81918.1};
OS Acinetobacter calcoaceticus (strain PHEA-2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=871585 {ECO:0000313|EMBL:ADY81918.1, ECO:0000313|Proteomes:UP000007477};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PHEA-2;
RA Zhan Y., Yan Y., Zhang W., Chen M., Ping S., Lu W., Lin M.;
RT "The genome sequence of a nonpathogenic wastewater-adapted bacterium
RT Acinetobacter calcoaceticus PHEA-2 and comparative genomics insights into
RT environmental adaptation.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADY81918.1, ECO:0000313|Proteomes:UP000007477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHEA-2 {ECO:0000313|EMBL:ADY81918.1,
RC ECO:0000313|Proteomes:UP000007477};
RX PubMed=21441526; DOI=10.1128/JB.00261-11;
RA Zhan Y., Yan Y., Zhang W., Yu H., Chen M., Lu W., Ping S., Peng Z.,
RA Yuan M., Zhou Z., Elmerich C., Lin M.;
RT "Genome sequence of Acinetobacter calcoaceticus PHEA-2, isolated from
RT industry wastewater.";
RL J. Bacteriol. 193:2672-2673(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; CP002177; ADY81918.1; -; Genomic_DNA.
DR RefSeq; WP_014206903.1; NC_016603.1.
DR RefSeq; YP_004995600.1; NC_016603.1.
DR AlphaFoldDB; F0KF50; -.
DR STRING; 871585.BDGL_001332; -.
DR GeneID; 11639513; -.
DR KEGG; acc:BDGL_001332; -.
DR PATRIC; fig|871585.3.peg.1326; -.
DR eggNOG; COG2303; Bacteria.
DR HOGENOM; CLU_002865_7_1_6; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000007477; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Reference proteome {ECO:0000313|Proteomes:UP000007477}.
FT DOMAIN 80..103
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 254..268
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 82
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 218
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 535 AA; 58608 MW; 1A5E7763C4145FB5 CRC64;
MNQQYDYIVI GAGSAGCVVA ARLLEAMAGR VLVLEAGSRD SSMFHTIPAT VVKVFQQKSW
QYMTVPQKYC NHREMILAQG KVLGGGSSVN GMIYCRGQRQ DYDLWSSEWG CNQWSYQHVL
PFFKKAEKNE SLADEYHGQD GILPVSENRY RHPLTLACIK AGQQMGMNYV NDINGWDQAG
VGFYQTTTQN GSRASTSKTY LKSVENHPDL TVITDALVHK IETQGDQVTG VTYSVGGKSP
ITVQVQKEVI LSAGAIGSPK VLLLSGIGPK QHLDELGIEC IRDLPVGENF HDHLHMSVNA
IVTTNNSLLG EDQGLTAVRH FLQWCFTRSG LLTTNILEGG GFIDTNNNGR PDVQFHFLPV
LDNFDNTPGE KATAQAHGLT IKVGHVQPKA RGILRLSSKD PKDLPVIDPN YLGHQEDIDA
NIRAVQAGLR LLQQPALKAI VKEVAEPANI DPDDIEAIDK WMRQNIKTVY HPAGSCKMGN
APQDSVTDQT LKVHGFKNLR VVDCSICPQV PSGNTNAIAI MIGERGADFI LNQVA
//
