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Database: UniProt
Entry: F0P2E9_WEEVC
LinkDB: F0P2E9_WEEVC
Original site: F0P2E9_WEEVC 
ID   F0P2E9_WEEVC            Unreviewed;       722 AA.
AC   F0P2E9;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   12-AUG-2020, entry version 46.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=Weevi_0033 {ECO:0000313|EMBL:ADX66761.1};
OS   Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 /
OS   NCTC 11634 / CL345/78).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Weeksella.
OX   NCBI_TaxID=865938 {ECO:0000313|EMBL:ADX66761.1, ECO:0000313|Proteomes:UP000008641};
RN   [1] {ECO:0000313|EMBL:ADX66761.1, ECO:0000313|Proteomes:UP000008641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 /
RC   CL345/78 {ECO:0000313|Proteomes:UP000008641};
RX   PubMed=21475590;
RA   Lang E., Teshima H., Lucas S., Lapidus A., Hammon N., Deshpande S.,
RA   Nolan M., Cheng J.F., Pitluck S., Liolios K., Pagani I., Mikhailova N.,
RA   Ivanova N., Mavromatis K., Pati A., Tapia R., Han C., Goodwin L., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA   Brambilla E.M., Kopitz M., Rohde M., Goker M., Tindall B.J., Detter J.C.,
RA   Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA   Kyrpides N.C.;
RT   "Complete genome sequence of Weeksella virosa type strain (9751).";
RL   Stand. Genomic Sci. 4:81-90(2011).
RN   [2] {ECO:0000313|Proteomes:UP000008641}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 /
RC   CL345/78 {ECO:0000313|Proteomes:UP000008641};
RX   DOI=10.4056/sigs.1603927;
RA   Lang E., Teshima H., Lucas S., Lapidus A., Hammon N., Deshpande S.,
RA   Nolan M., Cheng J., Pitluck S., Liolios K., Pagani I., Mikhailova N.,
RA   Ivanova N., Mavromatis K., Pati A., Tapia R., Han C., Goodwin L., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Brambilla E.,
RA   Kopitz M., Rohde M., Goker M., Tindall B., Detter J., Woyke T., Bristow J.,
RA   Eisen J., Markowitz V., Hugenholtz P., Klenk H., Kyrpides N.;
RT   "Complete genome sequence of Weeksella virosa type strain (9751T).";
RL   Stand. Genomic Sci. 4:81-90(2011).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP002455; ADX66761.1; -; Genomic_DNA.
DR   RefSeq; WP_013597157.1; NC_015144.1.
DR   STRING; 865938.Weevi_0033; -.
DR   EnsemblBacteria; ADX66761; ADX66761; Weevi_0033.
DR   KEGG; wvi:Weevi_0033; -.
DR   eggNOG; COG0370; Bacteria.
DR   HOGENOM; CLU_013350_3_0_10; -.
DR   KO; K04759; -.
DR   OMA; MEMPDYE; -.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; WVIR865938:G1GRF-32-MONOMER; -.
DR   Proteomes; UP000008641; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008641};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM        317..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        393..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        430..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        472..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        495..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        557..575
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        587..612
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        619..638
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        658..675
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        695..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   DOMAIN          29..191
FT                   /note="FeoB-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51711"
SQ   SEQUENCE   722 AA;  80531 MW;  34C96D3397FA1E41 CRC64;
     MKPNIACEIC EFNYSSDLKK LGDFSGKFDF TIALAGNPNT GKSTVFNSLT GLKQHTGNWP
     GKTVTRAEGS FSYHNKTYKI IDLPGTYSLL STSDDEQIAR DFVLFGQPDV TVVVVDASRL
     ERNLSLVLQI LEITNKVVLC INLMDEARRH HIEIDSRTLS KDLGIPVVET SARSKEGIPE
     LLVAIRQVAE GDFIARKIPR FQLSDNTEKA VNDLSGRLEK LFPTLPNTHW LAMRLIEGDA
     SILSFLEEKI DSKNELYDLI SQAEKYKKEL GDDYRNDVVE AIYSKAAKLV NDNVTTDKNR
     RSFRLDRSID RIVTHRFWGF PIMLFLLGVV LWLTIVGSNY PSELLSKLLL ENVYPFLKQG
     AASLKFPWWL SGFLIDGVYM STAWVVSVML PPMAIFFPLF TLLEDFGYLP RVAFNLDRLF
     KKSGAHGKQA LTMTMGFGCN AAGVVATRII NSPREKLIAI ITNNFSLCNG RWPMQILIAT
     IFLGVLVPAK WSGTISMLAV IFIAVLGIAF TFFTSWLLSK TLLKGQASFF TLELPPYRPP
     RFFQTIYTSI IDRTLIVLWR AIVFAAPAGA VIWLISNIPI AHQSLAIWII DALNPFGVFI
     GLNGVILLAY IVAIPANEIV IPTILMLSVL VLGDSTLGEG AGVMFEGSSG EIATLLHTAG
     WTTLTAVNLM LFSLLHNPCS TTIYTIYKET GSRKWTVVAT FLPIIYGFIV CFLVTRIWHL
     YS
//
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