ID F0RXL8_SPHGB Unreviewed; 605 AA.
AC F0RXL8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Polysaccharide biosynthesis protein CapD {ECO:0000313|EMBL:ADY12068.1};
GN OrderedLocusNames=SpiBuddy_0228 {ECO:0000313|EMBL:ADY12068.1};
OS Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy)
OS (Spirochaeta sp. (strain Buddy)).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158189 {ECO:0000313|EMBL:ADY12068.1, ECO:0000313|Proteomes:UP000008466};
RN [1] {ECO:0000313|Proteomes:UP000008466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1886 / DSM 22777 / Buddy
RC {ECO:0000313|Proteomes:UP000008466};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Mikhailova N., Pagani I., Ritalahti K.M., Loeffler F.E.,
RA Woyke T.;
RT "Complete sequence of Spirochaeta sp. Buddy.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; CP002541; ADY12068.1; -; Genomic_DNA.
DR AlphaFoldDB; F0RXL8; -.
DR STRING; 158189.SpiBuddy_0228; -.
DR KEGG; sbu:SpiBuddy_0228; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_12; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000008466; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008466};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 281..560
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 605 AA; 67807 MW; 01EDEADBB46A79CF CRC64;
MGSSVRNRIQ RQLLLMAIDA ILLCICAALS LWIVYATYDA TVVMFTLFAS MILLLSLSMT
RFYYIRVSEG SLDLVNRAVA GFLLPALVSV LLPLFLQGIH SLWIPYFVVF WGSSFLTMLG
IRFAYRSFRN YYTRQTHNNN PRTVIYGAGE LGNALVRQYQ RGKLPYHIAA FIDDNAALKG
TYLLGIRVWG TVDDLSEVLA QVHAKVLIIA ITHIDQARML TAIDAARDAG CDIKVIPSLF
EMQQGAKELD LRNLDYGDLL GRSLISIDKE PIKKMVLQKR VLITGAGGSI GSEICKQLLT
YGPAQLILLD IDETELHDLS LRLHNYQKEW SDLVVPVVCD IKNRKKIDRI MEQYKPQLVF
HAAAYKHVPL QELYPEEAIT TNILGSYAVL KSAKEHRVEK VVVISTDKAV NPTNVMGATK
RVVELMAGML NSSETEMVCV RFGNVLGSRG SMLPLFMEQI KAGVPITVTH KDIIRYFMAI
PEAVGLVFKA ASMAKGGEVM VLDMGQPVRI YDFAEKLVKY YGDGRSQVIV TGLRPGEKLY
EELLANKDTT IATEDKLVFK AQVSNHELSE LTFLNHYLTT FQNGNPDEML AMLHQLVPEF
NNPKM
//
