ID F0RXR4_SPHGB Unreviewed; 574 AA.
AC F0RXR4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:ADY12191.1};
GN OrderedLocusNames=SpiBuddy_0355 {ECO:0000313|EMBL:ADY12191.1};
OS Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy)
OS (Spirochaeta sp. (strain Buddy)).
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC Sphaerochaeta.
OX NCBI_TaxID=158189 {ECO:0000313|EMBL:ADY12191.1, ECO:0000313|Proteomes:UP000008466};
RN [1] {ECO:0000313|Proteomes:UP000008466}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1886 / DSM 22777 / Buddy
RC {ECO:0000313|Proteomes:UP000008466};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Mikhailova N., Pagani I., Ritalahti K.M., Loeffler F.E.,
RA Woyke T.;
RT "Complete sequence of Spirochaeta sp. Buddy.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002541; ADY12191.1; -; Genomic_DNA.
DR AlphaFoldDB; F0RXR4; -.
DR STRING; 158189.SpiBuddy_0355; -.
DR KEGG; sbu:SpiBuddy_0355; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_6_1_12; -.
DR OrthoDB; 367563at2; -.
DR Proteomes; UP000008466; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ADY12191.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008466};
KW Transferase {ECO:0000313|EMBL:ADY12191.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 400..571
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 574 AA; 65094 MW; 83181655C1B3B616 CRC64;
MELSKAMSEK VNLDAMRKVF FRNNLFAFLA LLFVPIVVMG SLSMYLLHGY IRKNLDKETQ
ILLEQLVSKV ATVTDQFNPL ILTVDIDGQS SYVARKLLDS VEMSYTDIFL LNNIKDQLSS
MRNAREYIHS INLYFTNDHG YYLSDTGKHS LTPKDDYWFD AYVSQKETQR SWTQTNEQSL
AGGFSFKLLS IFHILGNGEG VIVFNLRISM LDSLLNAGLL AAGHQALVSG VDGSVLFGSA
PEPETRQRYS VRTEVAKPSG WTLTLYSDKG VIFLVYRRVL TLIILLSLLS LVIGVVLSIW
LTQRRTRQIN AVIHLLEAAR DNESLPQIPK RQGPTYGYII HQIINTFLQQ SYLQTQLEAR
KYKLKTAQLM ALQAQLNPHF LFNTLETLNW KVYEMTDKPN QVNQMIEHLS DLMRYSLSSI
EDMVSLDEEL QSIRSYLALQ AIRYQDKFEA VYTIAPEALG FRMPRMLLQP IVENALYHGI
KMKKEQGTIT IEARVVADAL ALSISDDGVG MEKHVLESLT QSFSDPEQVR TDHIGLANVN
ARLFLLYGTT LSLCSEPTVG TVVTMTIQKK NKET
//
