ID   F0SQZ3_RUBBR            Unreviewed;      1129 AA.
AC   F0SQZ3;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 65.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   OrderedLocusNames=Plabr_2614 {ECO:0000313|EMBL:ADY60214.1};
OS   Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM
OS   15109 / NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis).
OC   Bacteria; Planctomycetota; Planctomycetia; Planctomycetales;
OC   Planctomycetaceae; Rubinisphaera.
OX   NCBI_TaxID=756272 {ECO:0000313|EMBL:ADY60214.1, ECO:0000313|Proteomes:UP000006860};
RN   [1] {ECO:0000313|Proteomes:UP000006860}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448
RC   {ECO:0000313|Proteomes:UP000006860};
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G., Lu M.,
RA   Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Tindall B., Pomrenke H.G., Brambilla E.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Planctomyces brasiliensis DSM 5305.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; CP002546; ADY60214.1; -; Genomic_DNA.
DR   RefSeq; WP_013628938.1; NC_015174.1.
DR   AlphaFoldDB; F0SQZ3; -.
DR   STRING; 756272.Plabr_2614; -.
DR   KEGG; pbs:Plabr_2614; -.
DR   eggNOG; COG3857; Bacteria.
DR   HOGENOM; CLU_010384_0_0_0; -.
DR   OrthoDB; 5487982at2; -.
DR   Proteomes; UP000006860; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.320.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR049035; ADDB_N.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011604; PDDEXK-like_dom_sf.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   PANTHER; PTHR30591; RECBCD ENZYME SUBUNIT RECC; 1.
DR   PANTHER; PTHR30591:SF1; RECBCD ENZYME SUBUNIT RECC; 1.
DR   Pfam; PF21445; ADDB_N; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006860}.
FT   DOMAIN          15..270
FT                   /note="ATP-dependent helicase/deoxyribonuclease subunit B
FT                   N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21445"
FT   DOMAIN          305..668
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13361"
FT   DOMAIN          790..1086
FT                   /note="PD-(D/E)XK endonuclease-like"
FT                   /evidence="ECO:0000259|Pfam:PF12705"
SQ   SEQUENCE   1129 AA;  127656 MW;  19BE82F8703107DD CRC64;
     MLKILATQVG QPATELCLAE YRTALKSVAK RGGIGEVLWL TPTHRSAQAV LKRLLDDDLA
     CCWAPGVMTF EQFAERVLRG AGQPASLLNP AERRMLVKST ISDVRRDGEL QYFNRVAETR
     GFGNQLGRFI AELKREEAWP DLWLNQLTDR PDSPKDRELG LLYDRYQQRM LAWDKYDPEG
     RFWLARRELT NGRWDAFPEL QLVVVDGFSD FTTTQQEMLL LLADHAREVL LALPGETGSD
     RPELFSRSGG TAAALRATAK RRQIETAVWN GQKQEQTVLA SRPIGLQTLA RNLFKNVRRI
     IPAEVAEGVH CVAALGHQAE TREVARAVKQ LLLDGVPAEE ISVTCRQPEE YAALVDSVFS
     DAGLPYQIDR TLPVSSLPLA RAFSAILGTI QEDWSYATLK KLLRHTPLSW ADWDNAAQRC
     RNVLHVLRLL NLQGGRLEIL RTLQSLASRA EVERDAEENE TFNDRSALYR EAHETLAKLD
     EQLRPLAKSG SYSEQVGRLL AIGRELFTDN QSKEKTEQET PTSASGRSWE SQWDLLAGML
     RESAEFQDRL SKPPGRRVSW ADFTEWLEDQ FQSQMLPPEK ARAGHVLILN AEQARHLDVP
     YLFVMGLQEG SFPSRQGQPP FYSEQERRQW NQTGINLIVE GARYQEEMLL FYRLVTRAQR
     QLTLTYSRVN STGGPLYASP FYQAVRELFT AESLGEQQVG SLSPVPEQNE LLTASDCRLR
     SVVEMGGKDA ALLSWWASQP DLSPSFHSLR AAARMNSHRF ETPGFTAYEG LLEAGDNRRW
     LQQRFPADYT FSASRLEGYA SCPYRFHLDH ILGLDPVQSP RLATDHRRRG NVVHDLLAGL
     YDSADDSSTA EGLADRFQQM VVEAFERTLS RSELRQALDE VEQQLLTEWA DLYDAQAESY
     YDQYAADWVS PPRPQYRELT FGREDATSEQ NESFPPVAFG DGEDVVLVEG RIDRIDVGEL
     AEGPVFNLID YKTGEPPRMK AEQLSRGTQL QLALYAVAIT RLKLVGEDAV PYLIGYWGIR
     EKGFVPQLTK SGKKWTPLSE EMLREWEQTL DRLLPHMVAC LRDGQFPVFN EDEHCVSFCP
     YRMVCRIGQV RAVAEPLQKI WTPVPIDSPE AAELLDGPDS TNATDSPTC
//