ID F0T8J4_METLA Unreviewed; 800 AA.
AC F0T8J4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Metbo_1514 {ECO:0000313|EMBL:ADZ09745.1};
OS Methanobacterium lacus (strain AL-21).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=877455 {ECO:0000313|EMBL:ADZ09745.1, ECO:0000313|Proteomes:UP000007490};
RN [1] {ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|Proteomes:UP000007490};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Cadillo-Quiroz H.,
RA Imachi H., Zinder S., Liu W., Woyke T.;
RT "Complete sequence of Methanobacterium sp. AL-21.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADZ09745.1, ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|EMBL:ADZ09745.1,
RC ECO:0000313|Proteomes:UP000007490};
RX PubMed=24449792; DOI=10.1099/ijs.0.059964-0;
RA Cadillo-Quiroz H., Brauer S.L., Goodson N., Yavitt J.B., Zinder S.H.;
RT "Methanobacterium paludis sp. nov. and a novel strain of Methanobacterium
RT lacus isolated from northern peatlands.";
RL Int. J. Syst. Evol. Microbiol. 64:1473-1480(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP002551; ADZ09745.1; -; Genomic_DNA.
DR RefSeq; WP_013645096.1; NC_015216.1.
DR AlphaFoldDB; F0T8J4; -.
DR STRING; 877455.Metbo_1514; -.
DR GeneID; 24964560; -.
DR KEGG; mel:Metbo_1514; -.
DR eggNOG; arCOG02352; Archaea.
DR eggNOG; arCOG06918; Archaea.
DR eggNOG; arCOG07605; Archaea.
DR HOGENOM; CLU_000445_114_71_2; -.
DR OrthoDB; 141807at2157; -.
DR Proteomes; UP000007490; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ADZ09745.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007490};
KW Transferase {ECO:0000313|EMBL:ADZ09745.1}.
FT DOMAIN 270..312
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 398..470
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 473..525
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 578..790
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 516..550
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 800 AA; 91996 MW; F40C7E63271B4D77 CRC64;
MTANSDGSCL KITSTNLFLE SVMDIIREPL IVLDANLRVI TFNDPFSNYF NVDPSDTVGN
LIYDINNGEW DSPDLRRLLE DILPESPPIK DFEMNHFFEN GTPKILNLNA QSFECRDQKP
MILISINDIT EHKLTIEKLQ ESEKHFQAVQ KNSLDRFTIL KPVYDDQGEI VDFSYIYQNA
QAAKSTGRNS EEIIGLRMTE LWPTFTQTNF FNMYKEAVNT QEVVEFEEHY SSDGIDDWFY
ATVTPIPDGI AISIQIVTDH KKAQEKLVES KEKLNTLFEN LSVGISVIDN EGKVIYENPA
LERILGLSET ELKLGKYGER KYYNSDYSEI PPDELPSSRA FEEQTPIKDI EVGVLIDNNN
MIWTNVSAIP LSFPDWKMLL VTYDITKSKK VEEKLQESYE RFNLAQKVSN IGTFEWNIQT
GVNIWTPELE AIYGLKEGEF PGTQGAWEEL VHPDDKQKAI NGVDIALKTG EPTESEFRVK
WADGSVHWLL GRWQVIKGDD GELLKLIGIN VDITALKEYE FKQQNLLENE KELTNKLHIS
NQELEKVNIE LIHQQDVQNR LIRKLEVSNK ELEQFAYVAS HDLQEPLRMV TSFTQLLAMK
YKDKLDSDAD DYIEFIVEGS HRMKDLIDDL LAYSRLNTEK TEYQFSDLNQ LLDNVLLGMK
NTIVEEGVQI TRDELPTVRC DSSQLGQVFQ NLISNSIKFH KTNPKIHISA EETREEWIVG
VSDEGIGIDP EHQQQIFDVF KRLHSRKKYP GTGIGLSICK RVVERHNGKI WVESELGYGS
SFYFTLPKKA MKLNQSILEY
//
