ID F0TCJ5_METLA Unreviewed; 353 AA.
AC F0TCJ5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Methyltransferase MtaA/CmuA family {ECO:0000313|EMBL:ADZ09272.1};
GN OrderedLocusNames=Metbo_1025 {ECO:0000313|EMBL:ADZ09272.1};
OS Methanobacterium lacus (strain AL-21).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=877455 {ECO:0000313|EMBL:ADZ09272.1, ECO:0000313|Proteomes:UP000007490};
RN [1] {ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|Proteomes:UP000007490};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Cadillo-Quiroz H.,
RA Imachi H., Zinder S., Liu W., Woyke T.;
RT "Complete sequence of Methanobacterium sp. AL-21.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADZ09272.1, ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|EMBL:ADZ09272.1,
RC ECO:0000313|Proteomes:UP000007490};
RX PubMed=24449792; DOI=10.1099/ijs.0.059964-0;
RA Cadillo-Quiroz H., Brauer S.L., Goodson N., Yavitt J.B., Zinder S.H.;
RT "Methanobacterium paludis sp. nov. and a novel strain of Methanobacterium
RT lacus isolated from northern peatlands.";
RL Int. J. Syst. Evol. Microbiol. 64:1473-1480(2014).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002551; ADZ09272.1; -; Genomic_DNA.
DR RefSeq; WP_013644623.1; NC_015216.1.
DR AlphaFoldDB; F0TCJ5; -.
DR STRING; 877455.Metbo_1025; -.
DR GeneID; 10277474; -.
DR KEGG; mel:Metbo_1025; -.
DR eggNOG; arCOG03324; Archaea.
DR HOGENOM; CLU_040933_2_1_2; -.
DR OrthoDB; 124836at2157; -.
DR Proteomes; UP000007490; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR CDD; cd03307; Mta_CmuA_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR006360; Mtase_MtaA_CmuA.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR NCBIfam; TIGR01463; mtaA_cmuA; 1.
DR NCBIfam; NF040654; MtaA_Meth; 1.
DR PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR Pfam; PF01208; URO-D; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Methyltransferase {ECO:0000313|EMBL:ADZ09272.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007490};
KW Transferase {ECO:0000313|EMBL:ADZ09272.1}.
FT DOMAIN 4..349
FT /note="Uroporphyrinogen decarboxylase (URO-D)"
FT /evidence="ECO:0000259|Pfam:PF01208"
SQ SEQUENCE 353 AA; 38339 MW; E4D709857C05160A CRC64;
MNLKNNVLKV LSGEKTDLTP VISVTQLGVV EAMEQTDAFW PEAHEDADKM ATLGSSLYEL
VGLECARIPF CLTVEAEALG CEVDLGNEEK TPQIRSTPFK TASEIEVPAN FLSNGRIPVV
LEAIEKLKQK YGDTLPIIVG ITGPFTLTGH LLGVENLVRY MKTKPDEIET AIDNSLDACM
DYAEAISKVG PDIICVAEPT AAPELIDPLQ FKSMVKPALE DLANFIKTKK VLHICGSTQP
IIKDMATIGY DGISVEEKVD IKKAKEELEK GSNVMKVGGK SMPRGSSSIS KIIGNISTTQ
TLFRGTEEEI KNEVKMVLDA GIDILAPSCG LAPRSPLKNI EAMINARNKF FDQ
//
