ID F0U4M1_AJEC8 Unreviewed; 805 AA.
AC F0U4M1;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=5-oxoprolinase {ECO:0000313|EMBL:EGC41968.1};
GN ORFNames=HCEG_01330 {ECO:0000313|EMBL:EGC41968.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
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DR EMBL; DS990636; EGC41968.1; -; Genomic_DNA.
DR AlphaFoldDB; F0U4M1; -.
DR STRING; 544711.F0U4M1; -.
DR VEuPathDB; FungiDB:I7I53_06485; -.
DR HOGENOM; CLU_372126_0_0_1; -.
DR OMA; INHHPIN; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 2.
DR Pfam; PF02538; Hydantoinase_B; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008142}.
FT DOMAIN 11..168
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 188..283
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 291..333
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 599..667
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
FT DOMAIN 694..804
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 805 AA; 88800 MW; 03DB862200FB1F86 CRC64;
MDAPVQRRGI RISIDRGGTF TDCVGNPGSG KLENDIVIKL LSEDPNNYSD APLVGISRLL
SKLEGRKIPR GARLATNALL ERKGGRMALL VTKGFKDCLK IGNQSRPKIF DLAIRKPYVL
YEKSYRGAVK ILLQTLYDEG FRSIDVCLMH GYTFPDHETL IGRLARQTGF NHISLSHELF
PMVKLVPRAT SACADAYLTP AIRKYIPGFQ AGFEGRLGAS SLKEEHGSKR TRCEFMQSDG
DLVDIDNSGL RAILSGPAGG VVGNGLTSYV PLTDIPVIGF DMGLPALMLA GTLDINTVAA
GGGSRLFYRN VLFVVGPESA GAQPGPGCYQ SEGLDEHASA RLFKELTETV NTGLPDDQKM
TPRRSRLRAM ILRNIDWQLL VAHEVAMAEN LGIKQISVHR YSSVLPAYEM ALEDVVDESQ
ALESKVWFKN GGIITNLKPK MVTLKEAARG RLHDQGFNDE SIVFEEYLNM RYRGTESSLM
IINPKSQITA ELPENGGNWG FGKALSDRDI IVDDVRVRAI SKSFQLEEAQ PQNVGDEKKF
CVSQVYFEGG RRRTPVYKIE DLNVNNRIHG RNGPDHLDAV INIGASQFLD TKVSLDTVDP
VMLSIFGHRC MTIAEQMGRA LQKTSVSTNV KERFHYSCAL FDSDGGLVAN ALHLQVHLGS
MSTCAVENMG WKTQAGTPGF HAPSFKKVIP RSCTRCLANN INDLKAQIAA NHKGINHISV
LIKEYGEDTV QFYMNNIQDN AELSVRRLLK SVSKKNRRAD LVAVDYTDDG SLVRLKISID
AEKGEAIFDF EGTSSEVYGR FQFPS
//
