ID F0U6U5_AJEC8 Unreviewed; 1359 AA.
AC F0U6U5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Nucleoporin Nup157/170 {ECO:0000313|EMBL:QSS52049.1};
GN Name=NUP170 {ECO:0000313|EMBL:QSS52049.1};
GN ORFNames=HCEG_00886 {ECO:0000313|EMBL:EGC41524.1}, I7I53_07547
GN {ECO:0000313|EMBL:QSS52049.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|EMBL:EGC41524.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|EMBL:EGC41524.1};
RG The Broad Institute Genome Sequencing Platform;
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QSS52049.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H88 {ECO:0000313|EMBL:QSS52049.1};
RA Voorhies M., Cohen S., Shea T.P., Petrus S., Munoz J.F., Poplawski S.,
RA Goldman W.E., Michael T., Cuomo C.A., Sil A., Beyhan S.;
RT "Chromosome-level genome assembly of a human fungal pathogen reveals
RT clustering of transcriptionally co-regulated genes.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the non-repetitive/WGA-negative nucleoporin
CC family. {ECO:0000256|ARBA:ARBA00007373}.
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DR EMBL; DS990636; EGC41524.1; -; Genomic_DNA.
DR EMBL; CP069103; QSS52049.1; -; Genomic_DNA.
DR STRING; 544711.F0U6U5; -.
DR VEuPathDB; FungiDB:I7I53_07547; -.
DR HOGENOM; CLU_000429_0_1_1; -.
DR OMA; SWAPFQK; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR Proteomes; UP000663419; Chromosome 2.
DR GO; GO:0005643; C:nuclear pore; IEA:InterPro.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IEA:InterPro.
DR Gene3D; 1.20.58.1780; -; 1.
DR Gene3D; 1.20.120.1880; Nucleoporin, helical C-terminal domain; 1.
DR Gene3D; 1.25.40.440; Nucleoporin, helical domain, central subdomain; 1.
DR Gene3D; 1.25.40.450; Nucleoporin, helical domain, N-terminal subdomain; 1.
DR InterPro; IPR007187; Nucleoporin_Nup133/Nup155_C.
DR InterPro; IPR014908; Nucleoporin_Nup133/Nup155_N.
DR InterPro; IPR004870; Nucleoporin_Nup155.
DR InterPro; IPR042533; Nucleoporin_Nup155_C_1.
DR InterPro; IPR042537; Nucleoporin_Nup155_C_2.
DR InterPro; IPR042538; Nucleoporin_Nup155_C_3.
DR PANTHER; PTHR10350; NUCLEAR PORE COMPLEX PROTEIN NUP155; 1.
DR PANTHER; PTHR10350:SF6; NUCLEAR PORE COMPLEX PROTEIN NUP155; 1.
DR Pfam; PF03177; Nucleoporin_C; 1.
DR Pfam; PF08801; Nucleoporin_N; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 112..565
FT /note="Nucleoporin Nup133/Nup155-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08801"
FT DOMAIN 805..1199
FT /note="Nucleoporin Nup133/Nup155-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03177"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 411..433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1359 AA; 151058 MW; D59D89EB00565532 CRC64;
MTAPPLTPQR PLPGTYFQTP AHPNFNGPLF QSSTMSGGGG LPTTAAALPP QPLRARLPMT
TVKSRAENLN PRQRAALTID EALAQESRYP DLDSYLSQGF SSDYDIPTSA SWAPFQKVKM
YNIPDQIFDQ YNRAQVSTNM GLFAELNHAW VTIDNALYLW EYTHPNPQLV GFESQPNSIN
AVKLARPRPG VFLPSISHVL VISTTAEVLI LGLGCETSAS GTKTVTLYQT GMATSIRGLD
INVITSSNST GRIFFAGSAD NDVYELTYQQ EERWFQGRCG KVNHTSKSFA AFTPSIILSH
KPTEFVEQLV VDDSRNLLYT LSSNSSIRVF HLKPDGTVNL TITKRAIDIY SNLGHIISSN
ETLNPGVKIV SISPIPAAEA SRYHLMAVTA TGYRIYLSAT GSYSWSATPT ATNAPTSMQA
HHVRTPPSDN PASQLPQGRG VVGPPYQVLP GAKLAIHSLD PTRSAQRFPP GYFFCFTSKN
STNRADTLFI STPDSGRLSR PQESALPIKP GETAIWLTLG SRAEDIGLCT PEFTMQPQGG
FGNELAVQFD KPAAEIAVLT NTGIHVIRRR RLVDIFASLI RSDSGEEGLE TQVKSLIRLY
GRSETLATAL AVACGQGVEL SADSRLSKIN DPDVLEFARK VFIEFGGKPT FNENAVADNS
TPAIDAVIPS PRHAGIALYT SRLLRSIWKT VIAKQSRTPA GGVTISPSVD TSKLHSIQRD
LSALQDFFRT NKSFIEGLSG PEALSRAVTK QDEIALQGEH RALHSMVQLV SDTIEGISFV
LVLFDEQVHE IIALLPEETR QRFLTLTFEE LFSSSKGHDV AKELVKSIVN RNIAKGSNVE
TVAEALRRRC GTFCSAEDVV IFKAQEQLKR ATEAGGNSEL GRNLLNESLI LFRQVSENLS
MDYLQSAVEQ YIQNQFFAGA IQLCLSVAAH SDKANRALSW IMDGRPPEDP RQASYEVRQQ
CYDLIYKIIL TVDELSGQDP GFVDGQYTVI ARRKNEVYDV ISNCEDEVFL TSLYDWYLDR
GWSERLLEVK TPFVVTYLQR KSTEDLSHAD LLWRYYGQSS RFYDAASVQL QLAQSSFSLP
LSRRIEYLGQ ARANASVFTP NVSRASRQRL IQEISTLIDI ANVQDDLLQR LKEETRIAPE
RKATVLQEVD GEIMELNKLY NMYADPGGYY DVCLQIMHLA NYRNASDIKA CWHNLIQEVH
DEASAKGEPL PYEAVIEKIR GLSGRLRMSD TTFPIQILLP MLQRYVLEQQ LGVGPDSWIV
ELFLDLQVSH ELIYTVLESL FYNDEVPFHG KNRRYIGRDL LYLIARWFQE SLRVGAGAFG
SDIFASRVSE MLLLLQQSGL DDESVQACRD LRVKIERSL
//
