ID F0UAJ0_AJEC8 Unreviewed; 837 AA.
AC F0UAJ0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Transcription factor tfiiib complex subunit brf1 {ECO:0000313|EMBL:EGC43699.1};
GN ORFNames=HCEG_02914 {ECO:0000313|EMBL:EGC43699.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS990637; EGC43699.1; -; Genomic_DNA.
DR AlphaFoldDB; F0UAJ0; -.
DR STRING; 544711.F0UAJ0; -.
DR HOGENOM; CLU_010293_0_0_1; -.
DR OMA; AEPPCKV; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd20554; CYCLIN_TFIIIB90_rpt2; 1.
DR Gene3D; 1.10.472.170; -; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 1.
DR Gene3D; 1.20.5.650; Single helix bin; 1.
DR InterPro; IPR011665; BRF1_TBP-bd_dom.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR013150; TFIIB_cyclin.
DR PANTHER; PTHR11618:SF4; TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT; 1.
DR PANTHER; PTHR11618; TRANSCRIPTION INITIATION FACTOR IIB-RELATED; 1.
DR Pfam; PF07741; BRF1; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 138..220
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 238..322
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 631..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..588
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..650
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 785..816
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 90080 MW; 55AFCB1BA573585A CRC64;
MTSMRPPARF PRAPGGGIRG PVQRLASLRN PNPIPSPRPR LQQKPTTHPK TSTCPNPGCP
APNIVEDDGM KVCSGCGTVV SEANIVSEIT FGESASGAAV VQGTFVGAGQ SYGRSFGPGF
QRGGGMESRE ITEQNGNRYI AQLSRALNVP ESATKAAGQV FKLAVGLNFI QGRRTKTVAA
VCLYIACRRQ DGNTVMLIDF ADVLMINVFK LGRAYKALLD ELRLGGNVFI MNPIDPESLI
YRFAKQLEFG SSMMQVASEA VRIVQRMNRD WMITGRRPAG ICGAALILAA RMNNFRRTIR
EVVYVVKVTE LTIHQRLNEF KATESGDLTV DQFRSVQLEN AHDPPAFTQG KRLKQAMKQK
NATTEIANGD EGENTQQLTT TSSAPRPMRV DADGFAIPDV PIDPALLADK DGVPPSPSTT
KAKRGRPKGA KNFRPPPPTA SELASESALE SEMQELLTTG SNLLASTNST TSHTAPTAQL
PATPQPPKPI PSTPDIDASE FDSDPEVKYC LLSPAEVEIK ERIWVHENKD YLRTQQAKAL
KRALAAEEDL MNGRVPGSGM GRRPRKRRKG RMGDVGYLDG KEGEGEESMD GGVGGGGARG
TRASTPAEAT RRMLEQRGFS KKINYRLLEE MYEDGDERKE DKRRADSESG EGEGGGNGWW
RRKRRRSASV SSVRSSSVVP DRTAVAAAAA AGGLGIRGPV RERVVKGSRS GSSVPAFVSA
VPTIPTQAPA PAPAPALAPT SSSTQPQPTA TTLGEEAEAA TPTPPSTNPH EEILGYIPGP
ERGEEDADAD ADVDGEDTDD EEEEDVEEDV EEDDHVDEAF AGNYYGGASD DDDDYYF
//
