ID   F0UMB0_AJEC8            Unreviewed;       358 AA.
AC   F0UMB0;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=TAM domain methyltransferase {ECO:0000313|EMBL:EGC48102.1};
GN   ORFNames=HCEG_07317 {ECO:0000313|EMBL:EGC48102.1};
OS   Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS   capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN   [1] {ECO:0000313|Proteomes:UP000008142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA   Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA   Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA   Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA   McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT   "Annotation of Ajellomyces capsulatus strain H88.";
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS990640; EGC48102.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0UMB0; -.
DR   STRING; 544711.F0UMB0; -.
DR   VEuPathDB; FungiDB:I7I53_08463; -.
DR   HOGENOM; CLU_010595_0_2_1; -.
DR   OMA; KEIGHYQ; -.
DR   Proteomes; UP000008142; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR43591:SF31; LAEA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G01930)-RELATED; 1.
DR   PANTHER; PTHR43591; METHYLTRANSFERASE; 1.
DR   Pfam; PF13489; Methyltransf_23; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EGC48102.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW   Transferase {ECO:0000313|EMBL:EGC48102.1}.
FT   REGION          145..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   358 AA;  41145 MW;  39B5A8DC026CFD33 CRC64;
     MNHIVTPVIP WKLGTQSQAE NDEIQKELDL QQQHGSPEAN IDPYVDFRFE PNDKREQDRM
     DLLHFIYRCV LSRRLYCAPI APNPRRVLDL GTGTGNWAIE FADQHQKSQV LGTDLSPIQR
     ISIPPNCTFE IDDFEAEWPY IVAATDDTHA PKPSSPRADN RTDELHNNDN LTTSVPTPAT
     SPILFDFIHT REITGSVHDY SKLFERAYRH VAPGGYLEMQ SMEANFFSDD GTHERAVTAM
     QWQRLLVEAS RRFGKELGVE GGWKEGMEQA GFVDVEEVVF KVPLSPWPKD ARMKDLGRYQ
     ATHVQEMLQS YSLALFTRVL EWSKEELDVL LRAVGNDLKD MRSHLYTKVR VVYGRKRE
//