ID F0V7G4_NEOCL Unreviewed; 877 AA.
AC F0V7G4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=NCLIV_001430 {ECO:0000313|EMBL:CBZ49655.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ49655.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family.
CC {ECO:0000256|RuleBase:RU365057}.
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DR EMBL; FR823380; CBZ49655.1; -; Genomic_DNA.
DR RefSeq; XP_003879690.1; XM_003879641.1.
DR AlphaFoldDB; F0V7G4; -.
DR GeneID; 13440564; -.
DR VEuPathDB; ToxoDB:NCLIV_001430; -.
DR eggNOG; KOG2229; Eukaryota.
DR InParanoid; F0V7G4; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000007494; Chromosome Ia.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF08158; SDA1_HEAT; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 130..392
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 397..480
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 689..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 330..364
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 81..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..634
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 698..716
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..789
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..851
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..877
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 877 AA; 98461 MW; 93CB149C79D95FEA CRC64;
MEDPTDGGRR AASAPQSLPL LQNSLKRDPP AYFGEFQLQF DRLRGLLAVL EQQPQRPVKD
LRQLLMFLAH TSPCYSPRVS EDASKSREKK ETGQVDRHPS APPAFLPLSS FGAFGEDTAT
KGAGPRNYSA ELSAAIQRIL LQLSSSLHPQ TRQTLLLALL LLRRKQQLSC VELLRVSVQL
LQLNDKSCRQ TLFSFVTRDV AKLCLADRMQ QSFTLLSPEL FAMLARPACP AAARLALCCL
IQVYRQQRHS GGLSIHQNNK NFQKIVNASA ACTLAGDAKL ATSAALFLLG ELQSASSRIA
NVDDEDTDDE EDAAVEAEAR RLTRTQEGMA KKTASAKKKL KRAKAKLQRQ VARKQQRAEQ
QQLLGGVVAS ASILDLLFDP QGLAEKLFEM WERASWKYLQ PHQRLVSSLL AILATAVHEL
VPPQELLPVV KHIADVFINE TRGEEVITVG LNAITEICTR APLCMTKDLL SDLVEYRRER
KSKSVVMAAR RLMNLYRDVL PSMLPANARG KEAAMAVRSS QDETVSYGEF KPAENLTGLD
ELEKLQKLVK ARKRMREEEE DDEEHDEEDE DDEDEEDDED GEDDEDGEDD EELSEGDEEE
DAGDEDEEED DDEEEGDDED EEEDEEEDEE EEEGKDECNK RPKKKMRRAS PSPKEGGGSG
NSEEKDVSSS LAMDRILTPE EFHALRVLQA KRSVETAGRR PGAQKDDEEE HDRLLSLLSK
TPGVEAGLDE SEDPDSDASS DEEPERERNS LFVSSTELEG LAGRKRRQAR ERNRLKEEAK
MERKRGGKSA PWPFAKKQRE AAEASLAADP SKKHKTVVTG NAPQKLKARN KPLAMVRQSR
KLRDKKQQSV KQKLQNLKKQ IKNLKKSQVG RPRRRKR
//
