ID F0V8Q8_NEOCL Unreviewed; 778 AA.
AC F0V8Q8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=E3 UFM1-protein ligase 1 homolog, related {ECO:0000313|EMBL:CEL64694.1};
GN ORFNames=BN1204_005750 {ECO:0000313|EMBL:CEL64694.1}, NCLIV_005750
GN {ECO:0000313|EMBL:CBZ50099.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ50099.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|EMBL:CBZ50099.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ50099.1};
RA Aslett M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBZ50099.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ50099.1};
RA Reid A.J., Sohal A., Harris D., Quail M., Sanders M., Berriman M.,
RA Wastling J.M., Pain A.;
RT "Comparative genomics and transcriptomics of Neospora caninum and
RT Toxoplasma gondii.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
RN [4] {ECO:0000313|EMBL:CEL64694.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CEL64694.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SIMILARITY: Belongs to the UFL1 family.
CC {ECO:0000256|ARBA:ARBA00010789}.
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DR EMBL; FR823382; CBZ50099.1; -; Genomic_DNA.
DR EMBL; LN714476; CEL64694.1; -; Genomic_DNA.
DR RefSeq; XP_003880134.1; XM_003880085.1.
DR AlphaFoldDB; F0V8Q8; -.
DR GeneID; 13446157; -.
DR VEuPathDB; ToxoDB:NCLIV_005750; -.
DR eggNOG; KOG2235; Eukaryota.
DR InParanoid; F0V8Q8; -.
DR OrthoDB; 206220at2759; -.
DR Proteomes; UP000007494; Chromosome II.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0061666; F:UFM1 ligase activity; IEA:InterPro.
DR GO; GO:0071569; P:protein ufmylation; IEA:InterPro.
DR InterPro; IPR018611; Ufl1.
DR PANTHER; PTHR31057; E3 UFM1-PROTEIN LIGASE 1; 1.
DR PANTHER; PTHR31057:SF0; E3 UFM1-PROTEIN LIGASE 1; 1.
DR Pfam; PF09743; E3_UFM1_ligase; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:CEL64694.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 392..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 83857 MW; 81F737ADC5984738 CRC64;
MVSLEELQRQ FMAVQEAAPT QTLSERACVD IVVKLMEMKK IQLVTTTNGK EFVTFETLAQ
EIRTHLANQK GRVNVIEMAT ALGVSPDVVE AKTEELTRRS RHFMLLDGDL ISTVYLNSLA
AEIEELLEEK GQLTIAELSQ KYSLPADFLR QEIHERLGTV IHGELRDQYL TTAHFSRRVE
SIVRGVLTGA CRPVAVSAIS TEFNLPNDSV TNAAVQLIRL GQLHGRLQSG LFTPACFSSG
QSAKVTSFYK ANAFVPFSLA KDCGFSDVHG LLQKELLDGI PLATVYVHPQ LVAPLQANIQ
EAASAASWAD VNSLLPSAFS PEDVRMLLLL ATGEAAAGRK AGSSPSAASK KPLPVVAFED
GVVLSHGFLD VFCEAAAPFL AKKAASAAET AQAGGPTKHV EETSQAAGAP GDDSEEDGEG
RSRRRGKGSR RGKAPEGEKK KKASAQAPAS GASISLGDIE EACSGEAWAG ENPLADLWIT
LPPHVQQRLW ETVQARLNTH YQKCVADSRR SLREQQRVKT ERKAANLQEE FETIVLAVKG
LEALGILDDA KHPLVVHLFK SVVGPLLDSL VESAVAEATD EPPQVTAQNR RQCLEKARQT
GADVESLLRA CDIAQKRSGS DLVDALQGAA EDSHVLLLRL PDKRRMKQLV SSRKAASQAA
LSNSTACDPQ GVLHAALGLL LAQRLFPHGS ILFPKDFWAL TTVWALLEKG ETGAAAENGS
KGSLALADVQ PLWLAVSAEE EKTKGHGSDN DARGSDTLRA MESEASRLLD VFAERNQR
//
