ID F0VEF5_NEOCL Unreviewed; 367 AA.
AC F0VEF5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=GTP-binding protein 1, related {ECO:0000313|EMBL:CBZ52099.1};
GN ORFNames=BN1204_018880 {ECO:0000313|EMBL:CEL66061.1}, NCLIV_018880
GN {ECO:0000313|EMBL:CBZ52099.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ52099.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|EMBL:CBZ52099.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ52099.1};
RA Aslett M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBZ52099.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ52099.1};
RA Reid A.J., Sohal A., Harris D., Quail M., Sanders M., Berriman M.,
RA Wastling J.M., Pain A.;
RT "Comparative genomics and transcriptomics of Neospora caninum and
RT Toxoplasma gondii.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
RN [4] {ECO:0000313|EMBL:CEL66061.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CEL66061.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
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DR EMBL; FR823387; CBZ52099.1; -; Genomic_DNA.
DR EMBL; LN714480; CEL66061.1; -; Genomic_DNA.
DR RefSeq; XP_003882131.1; XM_003882082.1.
DR AlphaFoldDB; F0VEF5; -.
DR GeneID; 13444965; -.
DR VEuPathDB; ToxoDB:NCLIV_018880; -.
DR eggNOG; KOG1487; Eukaryota.
DR InParanoid; F0VEF5; -.
DR OrthoDB; 146471at2759; -.
DR Proteomes; UP000007494; Chromosome VI.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01896; DRG; 1.
DR CDD; cd17230; TGS_DRG1; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 6.10.140.1070; -; 2.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR045001; DRG.
DR InterPro; IPR031167; G_OBG.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR031662; GTP-binding_2.
DR InterPro; IPR006074; GTP1-OBG_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43127:SF1; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR43127; DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF16897; MMR_HSR1_Xtn; 1.
DR Pfam; PF02824; TGS; 1.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51710; G_OBG; 1.
DR PROSITE; PS00905; GTP1_OBG; 1.
DR PROSITE; PS51880; TGS; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494}.
FT DOMAIN 65..290
FT /note="OBG-type G"
FT /evidence="ECO:0000259|PROSITE:PS51710"
FT DOMAIN 290..366
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
SQ SEQUENCE 367 AA; 40833 MW; 8493C4D17A5A2B8C CRC64;
MSVLQRIAEV EAEIARTQKN KATNYHLGLL KAKLAKLRAQ LIEGSTKKGG GAGGEGFDVS
KTGDARVGLV GFPSVGKSTL LNKLTGTFSE VAAYEFTTLT CVPGVFKYKG AKVQLLDLPG
IIEGAKDGKG RGKQVIGVAR TCSLILIVLD VMKPITHKQI IERELEGFGI RLNKKPPNIT
FKKKDKGGIS VTHTVPLNNI DEETIKSICH EYRISNAQIA IRCDATADDI IDVIEGNRLY
IPCLYVMNKI DQITIEELDI ISKVPHYIPI SAHHEWNLDG LLEKIWQYLD LVRIYTKPKG
QIPDYNAPVI LNSHMRRVED FCVRIHKSLL DEFKLAIVWG KSVKHNPQKV GKDHELVDED
VVQIVKK
//
