ID F0VQ32_NEOCL Unreviewed; 692 AA.
AC F0VQ32;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Sec20 protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NCLIV_062550 {ECO:0000313|EMBL:CBZ55829.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ55829.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004163}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the SEC20 family.
CC {ECO:0000256|ARBA:ARBA00037934}.
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DR EMBL; FR823393; CBZ55829.1; -; Genomic_DNA.
DR RefSeq; XP_003885855.1; XM_003885806.1.
DR AlphaFoldDB; F0VQ32; -.
DR GeneID; 13441260; -.
DR VEuPathDB; ToxoDB:NCLIV_062550; -.
DR eggNOG; ENOG502SFHD; Eukaryota.
DR InParanoid; F0VQ32; -.
DR OrthoDB; 215618at2759; -.
DR Proteomes; UP000007494; Chromosome XII.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IEA:InterPro.
DR InterPro; IPR005606; Sec20.
DR PANTHER; PTHR12825; BNIP1-RELATED; 1.
DR PANTHER; PTHR12825:SF0; VESICLE TRANSPORT PROTEIN SEC20; 1.
DR Pfam; PF03908; Sec20; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 355..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 206..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 472..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 604..618
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..664
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..692
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 692 AA; 74035 MW; 58072DCB556EF932 CRC64;
MLQHLPPAEA VAQLQDVMRD LAILNDSLRS LLSDSAPGHE AQHDQLVHFR GRVARRISRY
ALLVRKSQIL VDRLLHLQEQ QMHGSNAAAQ GAERQGAAPL APLAPAALPS LPSLSCFLSL
SLSAPGTDAS KAAAAARLQR EQLLQLQQYH QQNLQTFKSQ LSAWWQRTER HFHTMRMANY
VNALEATENQ APSGHAPHAH AVGKLAEEAH ATRPTGEAAS AQAGGPQGAS SFAGGALGFT
EDSVPREEGR RAEARNAKDE AATLLNSSDV RPDVQRKASG EDGESGEKRQ SQLRDTRAVM
AEELQRMQET QRQLQKSSAA IEQTESTYNV FGDRLASAKG ILAALKKRAE TDSQLIWFAF
LFFLGCCAFV VLRRLGIIRL IISTACMACS IFSGFFATLL SNLEVTDLRP QDILPSSLSS
DSNFAPVLPA SLPYEPPAAP PLHLSESDGV SSPEHTSQPV VDLSLPSLTH AVEEPGASAG
PPVSTRTREV SSCTPQGQGY SRSPSNSESC HAPEPPSAQF SFSPMGKNRN RLASSPASAS
TSGSSPAASQ LSDSPRSTDS IAPVSPPSSS RVSSSASSSS PSSPSTSLLR PPLSPTGLGE
DRAAVDGDGS ERRVFAAGSR SESEASNGRE GRAESEDVEA RDDDEASEEG EDREGVEDME
DMDEKADREG EHAEAHKDRD ANDRNEEEDP KQ
//
