ID F0X9I4_GROCL Unreviewed; 1103 AA.
AC F0X9I4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Nitrite reductase {ECO:0000313|EMBL:EFX05412.1};
GN ORFNames=CMQ_3481 {ECO:0000313|EMBL:EFX05412.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX05412.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
CC -!- PATHWAY: Nitrogen metabolism; nitrate reduction (assimilation).
CC {ECO:0000256|ARBA:ARBA00005096}.
CC -!- SIMILARITY: Belongs to the nitrite and sulfite reductase 4Fe-4S domain
CC family. {ECO:0000256|ARBA:ARBA00010429}.
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DR EMBL; GL629735; EFX05412.1; -; Genomic_DNA.
DR RefSeq; XP_014174894.1; XM_014319419.1.
DR AlphaFoldDB; F0X9I4; -.
DR STRING; 655863.F0X9I4; -.
DR GeneID; 25976586; -.
DR eggNOG; KOG1336; Eukaryota.
DR HOGENOM; CLU_003291_0_0_1; -.
DR InParanoid; F0X9I4; -.
DR OrthoDB; 275583at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd19943; NirB_Fer2_BFD-like_1; 1.
DR CDD; cd19944; NirB_Fer2_BFD-like_2; 1.
DR Gene3D; 3.90.480.20; -; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR012748; Rieske-like_NirD.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR NCBIfam; TIGR02378; nirD_assim_sml; 1.
DR PANTHER; PTHR43809; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR PANTHER; PTHR43809:SF1; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF01077; NIR_SIR; 1.
DR Pfam; PF03460; NIR_SIR_ferr; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF13806; Rieske_2; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF50022; ISP domain; 1.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007796}.
FT DOMAIN 926..1012
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
FT REGION 837..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 866..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1103 AA; 119416 MW; 6719D2A0C83BCC54 CRC64;
MATNTRKKVV VVGLGMVGIS FIEKLLKLDA RARDYDIVVF GEEEHLAYNR VGLTTYFGHR
QAEKLYLNRR DWYESIADGA LRYHTSKRVA AIDTESKTVM CEDGSAEGYD ILVLATGSDA
VLPRQTPGHD AQGVFVYRNI ADLEKLIRYE SSGVGAVVGG GLLGLEAAKA MIDLGRFDKV
VVIERNSWVL SRQLDDEGGG MVVESVQKLG VEVLLRKRVK IVLTEGIEGE GGESKRVIGV
QFEDGEKLAL STVCFAIGVR PRDELARAAG IECAERSSGG VVVGDDLQTS AADVYAVGEC
ASWHGQTFGL IGPGVEMADV LAFNLTQAKL HKVRSFRRPD LSTRLKLLGV EVASFGDFFA
DRDGPMGLPA KAKRGKAGGE ARAAAGTAAV KALTYKDPFR GIYKKYIFTA DGRFLLGGMM
IGDTSDYVRL VAMVTKQKEL DRAPGELIVG ARASDEAGAN ELDDETQICS CHNVSKGAVV
AAVRDGGCTS LGAVKACTKA GTGCGGCVPL VTSIFRTAMA ALGNEVSQDV CAHFRHSRAD
LYHIVAVRGL KTLAEVMAAA GVRADSVGCE VCRPVVGSIL ASQWNGHVMR GPTQALQDTN
DRWLGNMQRD GTFSVVPRVA AGEITPARLV VLGEVARDFG LYAKITGGQR IDLFGARRPD
LPAIWQRLVD AGMESGHAYA KSLRTVKSCV GTTWCRYGVG DAVGLAVRLE ERFGLIATEK
GFNIYVGGNG GATPRHAELL ARDVAPADVV PILDRYLALY IRTADRLQRT ARWIEALPGG
VAYLRDVIVH DRLGLAAELE AQMAELVGSF FDEWAEALRD PALLARFRQF ANTEERLAGE
AERETERQQE RPVFEKRGME VEVEVEVDGG RVEKDPKKDP RKDPRKDPRK GLKDPEKDRD
FAALTNSWST LAWQPVLDVA TFDRQTGTAS TSSTTDVAAT TVKLGDTQLA LFRVRGHYYA
TQQMCPHKRA FVLSDGLIGD DPTDRQQPWV SCPLHKRNFD LGSGACRSDP ASGLSLATFA
VRVEPEPKPE QEKQTIAICL PPPAELDAAL GTARWRLRAG EAGPPQLAEL DRRLQPSLVG
RRASKTIDRR PAAPITAGGG LDW
//
