ID F0XRC0_GROCL Unreviewed; 684 AA.
AC F0XRC0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Rho GTPase activator {ECO:0000313|EMBL:EFW99697.1};
GN ORFNames=CMQ_15 {ECO:0000313|EMBL:EFW99697.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFW99697.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
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DR EMBL; GL629807; EFW99697.1; -; Genomic_DNA.
DR RefSeq; XP_014169429.1; XM_014313954.1.
DR AlphaFoldDB; F0XRC0; -.
DR STRING; 655863.F0XRC0; -.
DR GeneID; 25974384; -.
DR eggNOG; KOG4269; Eukaryota.
DR HOGENOM; CLU_017095_1_0_1; -.
DR InParanoid; F0XRC0; -.
DR OrthoDB; 1359393at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF125; GTPASE ACTIVATOR (BEM2), PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04450)-RELATED; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007796}.
FT DOMAIN 383..574
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 50..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 605..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 684 AA; 76404 MW; 9B0152FC0AE83860 CRC64;
MPSSKGNETG REAGNTVRKT APQPLALAES ALMASDRSLA DASLQIDSPA EYSIHSRSPR
SPNSPLRYND RSGSLVLSQT PVPAGKPPVH LAELISQPLA DSESSHHPSL STSTSSSQLQ
QPAQPPQQPP QQHQQKHYGH GRHRQNEDKT SKSNFFFHFD AEPTQAANSA ELPTRSNASL
VSSSTEAEIS SSNSRKGKPK SFGRLGRTRS NRDKNGNIIH SNTTTATNTP ASSMQDDASM
RMVEPPERAY QPAATLKPAA VMPHEPSHRE AKASRTRNHS AERVRPRDVP STRDGHQNKQ
NQTREREHVR AQPSSSRETG GYTFFSGLKN SRAADIFSKG FFGKSTRSGS TTEREPVVDD
EHYVLRVINR PLVEQTRMTR ISKRLEDSRD KTEFWMPAFP WRAIDYLNFK GTDVEGLYRV
PGSGPQIKKW QRKFDQEHDV DLLSQDDLYD INIIGSMLKA WLRELPDELF PKAAQERVAR
QCAGSERVPQ LLIDELSDLS PFNYYLLFAI TCHLSLLLAH SDKNKMDYRN LCICFQPCMK
IDAFSFKFLV CDWRDCWQGC RNEMRYIEEE YRIFGLPPPM GISTPRSQLP PGSDGLAQEQ
VADMRQISSS DSDRQLDQVD QPPLRRPPNM ETGSVASTST ISTTLTIDSQ RAATPPGQSG
EMRGDGRGQM RPLSPIKPLS PLGF
//
