ID F0XTK8_GROCL Unreviewed; 1037 AA.
AC F0XTK8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Cyclin dependent kinase inhibitor {ECO:0000313|EMBL:EFW98798.1};
GN ORFNames=CMQ_4650 {ECO:0000313|EMBL:EFW98798.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFW98798.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
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DR EMBL; GL630006; EFW98798.1; -; Genomic_DNA.
DR RefSeq; XP_014168281.1; XM_014312806.1.
DR AlphaFoldDB; F0XTK8; -.
DR STRING; 655863.F0XTK8; -.
DR GeneID; 25977885; -.
DR eggNOG; KOG0504; Eukaryota.
DR eggNOG; KOG1161; Eukaryota.
DR eggNOG; KOG2421; Eukaryota.
DR HOGENOM; CLU_002842_1_0_1; -.
DR InParanoid; F0XTK8; -.
DR OrthoDB; 4907at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd14483; SPX_PHO81_NUC-2_like; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR22958:SF23; DEPENDENT KINASE INHIBITOR PHO81, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G06020)-RELATED; 1.
DR PANTHER; PTHR22958; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF03105; SPX; 1.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51382; SPX; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000007796};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 17..181
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT REPEAT 385..412
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 417..450
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 452..484
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 707..1020
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 1037 AA; 112785 MW; 8E5311EE2059606D CRC64;
MLCSSAESRP VTLCRAKKFG KQIQKRQLEV PEYAASFVNY KALKKLIKRL SATPTLSAQT
IPHRSATPID SQAALQANRA TFFFQLEREL EKVNAFYLQK EAELKVRLKT LLDKKKVLRS
RGAGVSRRSA KFTTLQEGFQ QFANDLNKLQ QFVEINGTAF SKILKKWDKT SKLKTKELYL
SRAVEVQPFF NATVISELSD QATTSLQELG AWAEGDHEIR FDGRAPQPDH IVSSQHLLGT
DEGDADTLLL DTVLAGHLDS LRDLLGRMTT AAAAARGQND GTGNSLDIAL AERVTRTFLA
SINEGSQEAL KSLIETRLVD VHSEDDINET ASIKPPYTAT PGPDAIDLID HDNFTPLIHA
IIHGYLDCVS RLLEKSARLD PISDTDHVPL NLACEHGSDA IVELLLKYGA RILPDAEGLY
PQHLVARSGR APTLLLLLQQ YGANLNQVDK LYGWTPLVHA ASEGNVPCLQ ALLEAGVDPN
IVDEKDLPAM YYAAWEGNLE CMQLLTAINS RRSRPPVFQE SPFGFQPSPG VLGSLGSGSS
APIPMALDPD AIPVLELPPP IIPLRRYGHN FLDTKTVVQI SFDDQNGEPP LVFFHDGKYP
AARLTISSKV ADLIPKNIML PFQEDTRLVS FQVDNLDSFV LDFEVFPTYG AKIIAKTVAL
SSTFRALLNS SGNSCCLPLF DPRLRAIGQI SFHTQVVKPF PGKPLEIADF ETYWKATSQL
DGHPSTFIAG SSLSGDYVRV YVQNTRDGVP VLWPTWTVNC GGGGGCASTP GTCGGIDIPV
ARLTYDEFLT ATAAGPGRSQ LASLPKYSAC DAAIVHQVLA ASGVTLRDAL ALLPSGMHVN
LELLYPSADE ERVMGLGGSG SVDLNAFVDS VLAVVFDHAR AQRAHTPDVV RSMVFSSYNP
SLCTAINWKQ PNFPVFLCND LGREDDATVA TIVPEAILSS GRRTASVKEV VRTAQSNNFM
GLVCSSRLLD MVPALVDAIK SQGLILVVDK SAEQPRGFGP LPKGIDGVLK SDGVLRFNES
IDMEMDTAEE GELTGGW
//
