ID F0Y0N3_AURAN Unreviewed; 4557 AA.
AC F0Y0N3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=AURANDRAFT_61597 {ECO:0000313|EMBL:EGB11250.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB11250.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
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DR EMBL; GL833122; EGB11250.1; -; Genomic_DNA.
DR RefSeq; XP_009033639.1; XM_009035391.1.
DR EnsemblProtists; EGB11250; EGB11250; AURANDRAFT_61597.
DR GeneID; 20223538; -.
DR KEGG; aaf:AURANDRAFT_61597; -.
DR eggNOG; KOG3595; Eukaryota.
DR InParanoid; F0Y0N3; -.
DR OMA; TRMACHM; -.
DR OrthoDB; 312149at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR019148; Nuclear_protein_DGCR14_ESS-2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF34; DYNEIN HEAVY CHAIN, CYTOPLASMIC; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF09751; Es2; 2.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT DOMAIN 1240..1378
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1520..1661
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1871..2025
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3947..3966
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3974..4012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4172..4226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4281..4302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2696..2747
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4557 AA; 503599 MW; 19922A1A9FDB177C CRC64;
MSADRGFTAE TQATFGSSAG PPTSTGSANV LDASQLRSRL YCGPGSTRDR GGGLQPLAMF
SASGRQAARR LEPKMRALKG SKSTPGLFAR SLDGSDAASS ALGADRAAAT MTGRHILTKP
HKMRAKLAAP PEAVVAFAAA ATAAPEAAAI APPRADETAL VVAEPKKRSF LESLNLTPQQ
MASFIDDAGN FLYLTHSRDT LHAGSAYDLV VVEHALVDSG DYFTLSCSGM THFTGVNSDF
TPLHQWEREY GLFHEMRRIP FFAKYRAWKT FSVWKKNVKR NKVRAAILAL KGSLFLFIPS
LRDALLEIQA LCQETLALSL LEAEPGKTYE LDEFAAAQAH LQDRRAEALV RFSGDVQSLA
RTACDEVVDS FLRAAKIVAD HRMTFMERAS LRSECRKLTR FLRLVDFHVV NALRELALES
ARNALALAAP EIVPTHVIHR DEPPEAKGDD DVGLGGGETY GGDGEEDESA HAPLLRVEVS
FTKGSLVLSP SMRDVQKAFA DMLQACLKVV GIPDRIFAHP DLALYIMSDT DDAPGDVARE
ETSVQDLVAS EEKWKRASSA IGTALEAAYD AATDYATCVE PYCGKAQENG DFLEVHKDAL
GKDVNLEKYA HAITDYRAQA ADFATIPRSA DVGILRVDSL ALKRLLVPSP TRCLDALQAY
LPELMDIGFK QLLDQLGSIL PVVTGAPANV AVFVTKKRVV KEAQENYEGY KEAQQKLIAM
AELMESEDWP VPEDQKAHLV MADENMTTLD TGVQIAEGRE EEDTKRFATE VAEEVPRLKK
RIAEVREQLD QRIVASLDER PENVLAFLEI QSDALDELKS RSETLCDYQG ELGQDIDEYD
TLDEVAADLN LKLRLWRGVK EWSGLTAEWV VTPLSEIDAV ELEKHVQAYN KTVFQASKGL
PGNPVVPKLK ASVETFTPVL PVVVNLRNDA LQERHWAMIH DLVGFEIQGD AAFTLGDIIN
KGVTAHHAEI TAIATNATQE SVLEEMMAKV TKQWESTELI VMDYKDVKDL YILGDVSENI
AALDESLVTV NTVLGSRYVG GIRAFVERWR RDLILFQDTL DEWLACQRAW MYLETIFSSP
DIIRQLPAAA KQFQAVDKSW RSIMKSTADD PIAIKACCVK DRKETFISHN ATLDKIQKSL
EDDLEKLQRK KIVALVTTDL HARDIVEELR DKGVRDVGDF TWMQQLRYYW EHVVDTEDCL
IRHSDAVINY GYEYMGATSR LVITPLTDRC WLTLTGSYGL KLGAAPAGPA GTGKTESSKD
LAKAMAIQCV VFNCSDQIDY KMMGKLFRGL AQSGSWTCLD EFNRIDIEVL SVIAQQLLVL
REGRIAGKSS INFMGVEIKL LDHHVIITMN PGYAGRTELP DNLQVCFRPV SMMVPNYALI
AEIMLFAEGF GDAKTLSRKM CKLYILCSEQ LSQQPHYDYG LRAVKSVLVM AGGLKRDNPD
ISEDLVLIRA LRDSNLPKFL ADDIPLFFAI IADLFPGVVV PDNDYGEFQV TLEDEITKAG
LQNIPGFHKK VIQMFDIFNI RFGATIVGPT GAGKSTCYRI LAATMGSLFR AGSSNTQYQE
VRFEILNPKC ITMGELYGEV NMVTQEWRDG LASTIMRRAV GEESAVRKWT VFDGPIDALW
IENMNTVLDD NMTLCLANGE RIKLKIEMKM LFEVMDLAVA SPATVSRIGV VFMTPSDLGW
FPYVQSWAAD LPDQVPDHAR AHLLKLYDAY FQKALTFQRK KCKEPVGCVD IQLATSCAVI
FQSLFCGSES KVDFESYAKT PELLLRLVEK LWFFSFVWSV GGSIASEGHD GFDYFARDML
DQGGVNLDLP GAGLSYDYFV QVADQPGGKF LPWKQVVPSF KFQRDLPYTA IVVPTEDSTR
FSFLMRTLVT AMKPVFMTGV TGTGKTVMVQ SLLRSLEPLQ DEGGLGVVPT FLNFSAQTSS
LVTQSAIESK LEKKRKNLLG APAGKTCIIF VDDINMPLVE SYGAQPPVEL LRQFLDFKGF
YDREKLFWKD ITDTMLFTGA APPGGGRAEV TPRFTRHFNV LCVPPASDAA KTVIFESIFG
GFMTTFEKDL QKMVKGVVSA TIEVYNSISV ELLPTPAKFH YSFNLRDISK VFQGLLMVAP
SKVKDGETLS KLWLHESQRV FYDRLINVAD QEWFEKLACE LQTRHLGQMP QTPEQVFGEN
SVIFADFLKP GVELATRRYE LGNLELITRL LGDTLDEYNI TFPTQMNLVF FSDAVRHVCR
MSRILRQPRG NAMLVGVGGS GKQSTTRMAA FVAEMPCLQI EISRGYGLKD FREDVKKFMI
TTGVEGTSIV FLFTDTQVVE ESMLEDINSI LNSGEIPNLF PQDELDKICS DMIPVCDALG
VPASRDNCIA TFITRVWDKL HIVLCMSPVG DALRVRCRQF PSLINCTTID WFLGWPETAL
VAVAEHFLAS VKLGSGSDEL ELEHRSAIVR ICVLVHTSIT EAGDRFFNEL RRRTYTTPKS
YLDLISMYAS KLGELQSIVD VKIEQMTVGT EKLRDTNAIV DGLRGELKEL APVLEKKAVD
AEAMLKQVAI DQAEADVVRE KVAAEEAELS KQSEAVSKIA AEAQAELDVA MPALQAAVKA
LDSLTKNDIV EVKAFKSPPL AVKVTMEGIC IMLERKPDWD EAKKVLGDSQ FLDKLKTYDK
DNMKEAVIKK IQKYIVEPNM QIEVVTKVSS AAKGLCMWIH AMNVYHKVAK EVGPKREKVQ
KLTDQLNAAN ASLKEKQDAL QAVMDKVQAL QEQCDATVAE KTKLMEAQAQ TALRLQNAEK
LTSGLSSEGV RWKENLVNFN AQRVELIGDT LLSCAAISYY GPFTGVYREA LVESWLGTST
DLGLPCSKTP SLLNTVGDPV KVREWQTQLL PTDEVSTNNA ILVTEGKRWP LMIDPQAQAN
KWIRKMMERS DLLTTTMTDI NLLRVLENAI RNGKPLLIED VHEQIEPALE PVLAKATFNQ
GNRILIRLGD SNVDYDPAFK LFMTSKLPNP HYLPEVCIKT TIINFTVTME GLEDQLLGDV
VKAERPEVER KNVQLLLQMS ADKKKLAEIE AEILRRLSEA KGNILDDEEL INTLADSKKF
STMINERLEA AEVTKQEINE AREAYRTVAT RGSIIYFVIS DLGTIDPMYQ YSLQYYQVIF
NKCLQDAEAS KDQEKRLGIL IEYSTVVIYD NICRGLFEKD KVLYSALLAF SILRHASKIP
GDEWNLFIRG PGVPDRASQP KNPNPKALPE ATWDLVCGME FLLARDAGLD ENGDEVPAKA
SPYAGLTASL SKNWDAWEAW LGAVDPSAAP LPDPFEASVT KFSKLIIVKA LRDEFTLQAV
NNFVRYAFGD DLADAPSGKM DEIYDDLDNA TPCIFILSKG TDPTGMLFKL AKQKNYSDRL
QLVSLGQGQG PAAAALVDRG TRSGDWVLLQ NCMLAKSWMH DLELMVFELG EHREKNHPDF
RLFLTSSPAP YFPVSVLQNG VKMTNEPPKG IRANLIRSYQ NLVKPDEWET CKKSDAYKRL
LSGLCFFHAN VLERRKFGPL GWNIRYAFDE SDLETSMAIM RRFLDEQEVI PWDALRFVTG
HINYGGRVTD DWDRRALLCI LGIYFNERVM EPKDGGYVDY AFSASGIYKP ATTGPLEEHQ
AYFDTLPAVD QPEIFGMHEN ANITFNRAES SALMGTILAL QPRESSGGGG KSSDDIIIDQ
IDDIEGKMPE NLDEEDKGPT TFVLQPNGLL TSLDTVLLQE MVKFNRLMNR MRSSLRELRR
AIGGFVIMSS DLDDMYTAFL NNQLPPIWRK VSFETLKTLG SWVKDNLFRI DFMRSWLLGG
LPTSFALPVF FFPQGFMTGT LQTYARKHMV AIDTLEYEYE VLKLDGDPEA APEDGVICSG
LNLEGARWCF DTHMVVESRI GEMYTMLPMI HFKPAVGHTI PDGFYACPVY KTAERKGVLS
TTGMSTNFVV AVELPSSVAP ERWAKHRPLE MAAPSLSALV AVGARARDAA SNGDAKNGTP
IADDDVERYQ IQPSTRPAGP AAADAPAPRP TRGGTGCLLM APPPPRPRPP KKAVLEEEAY
VDEMRRIIDR DYFPGLAEGD ALPMTLDAFA ARHTSEDNAS FEEAQERSRL DHIRKYWWAY
DERSLLEAGV EVPDPTDPGR HLLSDGTRLS EARRLLADAA AAAAPKRGDE RRNGLDFAPH
EARPALLFPP RYDAPRETAL ALARGADIRG GIQRANTRFA PPAPARPRSR SASSSETGAW
PDLGDVASDS DGDSSAYPSA YDGGHDRLVP MTPRIHPGGE PGGASPLVTW GTMAATPLPL
DDGGLLSQPA NRREALGRSL DARAKRRQVP PPSPLRAALD ASKRRRTGYS SVIGDDYTTK
FLLKAKVAPK AIPLSFTIEN EVKDSVDGKL TAKYVEPTTG VSFDKLTLKG KTYGVEASKT
VSGIKFKGKV NPADASSAAL TAELKSDKNT VIASVDKKKL AGSGTVAPFK VGVFGGGFEY
PVSGGALSFS LGGSATVSGV FASCVYTPKK VFNFGMMFSP MPKLTVAATG DSTGADSATV
GLKHSGLGAF TLGLKTSAKA LSAVIVKKVG KDATAVFGAT AKYADMKPAF GFQLTIG
//
