ID F0Y227_AURAN Unreviewed; 3949 AA.
AC F0Y227;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGB11143.1};
GN ORFNames=AURANDRAFT_22564 {ECO:0000313|EMBL:EGB11143.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB11143.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
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DR EMBL; GL833123; EGB11143.1; -; Genomic_DNA.
DR RefSeq; XP_009034690.1; XM_009036442.1.
DR EnsemblProtists; EGB11143; EGB11143; AURANDRAFT_22564.
DR GeneID; 20219627; -.
DR KEGG; aaf:AURANDRAFT_22564; -.
DR eggNOG; KOG3595; Eukaryota.
DR InParanoid; F0Y227; -.
DR OMA; HAIVCER; -.
DR OrthoDB; 312149at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46961:SF5; DYNEIN HEAVY CHAIN 6; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT DOMAIN 696..1103
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1232..1558
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1732..1861
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2092..2172
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2230..2489
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2502..2848
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 2879..3104
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3349..3462
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3494..3635
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3642..3945
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 2734..2782
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 3949 AA; 445224 MW; 57DD93285CE1C80F CRC64;
MDRVVVLPKR EQWDRLLGVA LSLKPFDGPG VKAHALRGVA EAHVFGTPWL GPEEDRVPVV
EPELDELDEA DLPRVRSILA LVDEAVADYE AVMNEIVFVS DKLNVANYSS YLQLMLPAPP
PRAPPPRLGV VATPPHDFPR ITVDFRSATF LDSVEVVQAL TDTQMHAIAI HDLKILSTEH
AAPQSPDEFT TAQTAAVAAA LRTLKEQWVQ RTAASIRQDL ATTDRSVYNL EEGAMASYSR
PDNKLYLLLK RINYVMTHEL FLVTFESLTN YTNYVVDACK GQVTVNSTSD VECVYPDRKA
DEPPRMPPLF FMTPVEGRTF DYETPLSQME SCVASAFRHA IKELRAIPHV QRYIMERLFW
PRPEMIGAVT GEKVADFNGV ETYREDERWI GDLEESFVTA VRAAIDPART YLDCFHQWED
FLNLEVDEYV AGLTHAQLND EEVEEGEEPD APPVKVNLVV LKATLNTHRE EKARVEAMIP
GRPLSAGLCM LNAAALRDEL ANKHMAIMQS VLATHADHCS QVAVFLDQRF SKIEAALKKK
PRDIEETKEL EEYLTNVPND IRPLQEFIDE MRLMAAVLDG FEYRVDFDHF EQQGRAAYWP
CKIAQQSEET ARIIESSRER YLEDMMTEQE RFTKSLHALE AFANSFVQYE DLTQVKEAAA
RAVECMGKIT AATEKARLYN SREVLFEREV TDYAHLTQIK KAFEPYYALW NTSQKWLESS
KTWNDAAFQS LDAEAVESEV NDYSNAISKA SKFFERNDMG PQASIAKEIK EQVSAFKPNV
PIIVALRNKG MRERHWHEVG ESLGMKEFVP DESFTLAGML DLNPTSQIEL ITKVSEAAAK
EFNIEQTLDK MLQDWTPMEL QISNYRDTGT GVLKGVDEIT AILDEHVTTT QAMQFSAFKG
PFEERIESWN HKLYIISEVL DAWLNVQRNW MYLQPIFESP DINKQLPSEG RKFATVDKNW
KQTISSAKSN PIVMDFCDNE KLLERLKDSG TLLDQVQKGL NDYLETKRGV FSRFYFLSND
DLLSILSESK DVMRVQPHFK KCFEAINAVE FQPDLSITKM ISPEKEMVPM MDPVDPVGKN
VEDWMLEVEA MMRTSIRHVM DQAIQDYPKC ARTQWMQKWP SMCILNGSQM HWTSETEQFF
EEKGAEGPAL MLERQLEQLD AMVKLVRGDL PKAARAQVGA LAVIDVHARD VMKRLANDGV
SAKADFAWMS QLRYYWDDGD LWAEMVAARR KYGYEYLGNS FRLVITPLTD KCYLTLMGAL
QMILGGAPAG PAGTGKTETT KDLAKAVAMQ CVVFNCSDGL DYQAMGKFFK GLASCGAWAC
FDEFNRINIE VLSVVGQQVM SIQLAIKGHV EKIEFEGSTI KVKDGFGVFI TMNPGYAGRS
ALPDSLSALF RPVAMMVPDY ALIGEIMFFA YGFAAAKDLG RKMVTTFKLC SEQCSSQPHY
DYGMRAVKTV ITAAGNLKRK EPESDEMILL LRALQDVNIP KFLAGDLPLF QGIISDLFPG
KKRPVLDYGA LFSVMKLTIE EQGLQPHGWF IGKIVELYEM IVVRHGLMLV GPTGGGKSAN
LHVLENTLGE LKMRGEQGFA YEKVKIYQLN PKSITMGQMY GQFDENTREW QDGIMSTMYR
RAASSTTSDR KWVMFDGPVD AIWIENMNTV LDDNKKLCLV SGESVKMSGE MTMMFEVEDL
LVASPATVSR VGIIYMEPKA LGLDVLVQSW IEATLRKSPS LAATPLKATL VRMFDTYLNS
SIAFVRLYTK ELLPTMDNNL AQSLMRLMDC FLEPFEEKEG RDKPKQEDVD VFVAQVEARF
IFSLVWSVGC TGAATARRMY DAWLRAQLAT NQVALKFPEA GDVYDYVWSP DDGGQWRKWM
ETIDQFKVDN KLSFSELIVP TADSVRSTYV LAQLLKKRYH VMLVGETGTG KTVTISQYLQ
GSSKCEGAPI APEFTPLTMT FSAQTSANMT QDTLDGKFEK RRRGVFGPPA GKVMAIHVDD
LNMPMRETYG AQPPIEILRQ WFSQEGWYDR ANDLAFRRIV DVVFVASLGP PGGGRQEVTP
RFVRPFNVVG LSDISDNSKA GIFGTILGNF LEGFTPAISK LTSQIVLSTI NTFNTICETL
LPTPSKSHYT FNLRDLAKVF QGVLMGNAKM IDQADGVVRL WVHELKRVFE DRLTTTQDHE
WFMGHVESTV AKDFGIEWSK IMTNERLMYC DFLDPNADPR IYCEVTDIDQ LKQIVNDQLE
EHNGESKSPM PLVMFLDAIE HVLRIARILR QPQGNALLLG VGGSGRQSMS KMATYISGYQ
LFQVEIAKGY GLTEWRDDIR RCLLMAGVKD EPTAFVFSDA QVVMETFLED INNILNAGDV
PNLYGPEEMD SIMSACRIDC QKKQIPPTKI NIFAQYIIRV RRNMHICLCM SPLGETFRER
LRQFPSLVNC STIDWFTEWP AEALESVGMS ALVEKGQVPA DDRGMVVKMF KKIHQDVEHK
SADFWEMLRR HNYVTPTSYL ELLSSFATLL SYKREEVKTK KDRLQIGLDK LTSTKDLVAG
MQEELVALQP QLVTKGKEVD EMMIVIDQDK KAADEVKAKV LVEEEKANGI AERASAIAAD
AQKDLDEALP ALDAAVQCLK ELKKAHIDEV KALRNPPGGV RLTMEVACLY FEVAAIKKAD
PNQPGKKIED FFEPAQKVLL SDANRFLKML QDYDKDHIPD KVIKKVSPYM SNPDFTVEQV
EKASVACRAI CMWAHAMHKY HFVALGVAPK KAKHAEATAE LDSAMAVLNA AQSRLKEVVD
KLDKLEQSLK AAVDEKQSLA DKEIECKTRL SNADKLIGGL GGEQTRWAAT VEHLSEALEN
CVGDVLVSAG TVSYLGPFTS EFRKDVVDGW QSTLGELGIK ATPGCDLVQT LVEPVKLRMW
QMYGLPTDNL STQNGIMLDR ARRWSLFIDP QGQANRFLRT MAKDKEMCKN GFDVTKLSDK
NFLRTLENAV RFGKWALLEN IGETLDAALE PILLQQTFKQ GGQDMMKLGE STIPYNEEFR
LFLTTKMPNP HYSPEVQVKI SLVNFTVTQS GLEEQLLGAT VELEMPDLAE KKSQLVVQQA
QMNKQLFDIE SEILLLLSNS TGNILDDTNL IETLAQAKKT SDEVQAKMKD AEITTVEVNK
SSEEYRPVAK RASLLYFCLA DLANVDPMYQ YALPWFKELF ATGVKRAPMS NKIEERIVNL
NEFFTYFVYT NVCRSLFERH KLLFSFLATI KIMMGDDKVD QLEWRFVISG QTIGSIDLPN
PDPDWIEPNV WSEIKALGGL NEAFAALPAK FGESLAKWKR VYDAIDPQAS KLPAPFHEMS
SLQSLCILRC LRRDKLMDGV QLFVAKEMHQ KYTEPPPFDL PLCFDDSSNI TPLVFVLSTG
SDPNKDILEL AERQGMLDKM TSIALGQGQG KIAEKLIDKS TGDGSWVLLQ NCHLCISWLP
TLERIVESFD KDKININFRL WLTSMPTAAF PVAIMQVSVK MTKEPPRGLR ANLKTTFLKM
NDEGLSATNK PSEYRKLLFG LCFFHALIIE RKKFGPLGWN VGYTFNETDL DICIAQLELY
VNQYDDIPYA VLSQLTSVVN YGGRITDDKD MRTADIIVSD FMTPQILADN YRFSRSGTYY
SIAADESSPL ASYLDYIDSL PMMPEPEVFG MHDNASITFA LNEADENCAI IQSLQPRTSG
GGGMSREDVM AKAAQDMEAT LPVPWDVDAV YLLYPTAYDE CLNTTIVQEV TRFTRLGKVM
VETLKTFQLA LKGLVVLSSE LEAMGNFIYD GKVPELWSSK AYPSLKPLPL WYEDLLKRLT
FLQGWIDKGI PDVLWISVFF FPQGFMTANV QNFARRTSVP VDTVEFGHIL LAEAADELVA
KPRDGCYVNG LFLEGARWDK RKKTLTDPRP KELFAPMPVI HLLPQVDRET PTKGIYRCPV
YKILTRTGTL STTGHSTNFV FWLEVPSNKL CDQSYWIKAG CACFCALKY
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