ID F0YAH1_AURAN Unreviewed; 1700 AA.
AC F0YAH1;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGB07930.1};
GN ORFNames=AURANDRAFT_64531 {ECO:0000313|EMBL:EGB07930.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB07930.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Folate-
CC biopterin transporter (TC 2.A.71) family.
CC {ECO:0000256|ARBA:ARBA00007015}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL833129; EGB07930.1; -; Genomic_DNA.
DR RefSeq; XP_009037303.1; XM_009039055.1.
DR EnsemblProtists; EGB07930; EGB07930; AURANDRAFT_64531.
DR GeneID; 20224879; -.
DR KEGG; aaf:AURANDRAFT_64531; -.
DR eggNOG; ENOG502RZXS; Eukaryota.
DR InParanoid; F0YAH1; -.
DR OrthoDB; 103849at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR039309; BT1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR31585; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR31585:SF0; FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC; 1.
DR Pfam; PF03092; BT1; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 464..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 495..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..546
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 586..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1334..1398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1419..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1618..1700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1350..1365
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1368..1389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1461..1482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1559..1574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1684..1700
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1700 AA; 178503 MW; 726E3105D0BF1C37 CRC64;
MDLRMLLGLA RPAVVVVPGF LYGSEDFVGL AEALRRRGVD ATVAPIAWWH WIPCLGGRSV
RPILERIQCA VDYASSADVV AVEAPAPAYT PLDLWRDFRQ TPGGVMAVGG SADPDEFPDV
APCGGFGDAP PPRRACAIVG HSASGWISRI FLSSRTYGGK AYGGSGGRVS KLVTLGSPHA
ASEGVAFANV AWANREAAPV PALAVAGGGF GGATAESFTT DSYAFCGAPD AETCDGDGVT
PVASALDLPG AETLLLEGAT LHAPQFPRWL APQLHDAGVA GGTPWFGDDA RLDATSSAAS
GALRLAEQTA EQNTAKEKAS GTKGAAAAHA WAVALNKSER ATVGYKPSRP VVQGFAGSSA
SAAKMEEQAL LSDADRAAEV ASLKAAEAAN LATAKALYEQ QKMEGDEKEA RGRAESAELL
DPFALGTVAM LVGAFVDNVC SALYDVPLKY YLYDDLGVSV RAYYVLSACT SIPSSLLPFF
GLLALVPIRG CHHKFYWMLG YALSCACYLV LGTSSGSPSF SAIVWWLTCA AVGSSLRSTM
LAMMMVERTR HETLANRGLF SLYLASARAG QESEIPNFKA SYLGRFPLAS ASYCGAFVGQ
ALASVLYENE LGLGSWGGFT ISQIFVICGV APLVVVVPLA CFLKEVPSIA ARSTKSVAAR
ARFEFVAIWE TLQDKRIGCI LSFGLALYLL TVTNAAHSYL LLDGCDISEP EYCWLKIVQD
MTLWGVIVFY RQYLFEIDLH TLFVGAYVVR TLAKLNDCVA VVAGGANSAL PCLFWVGGDD
VTYDSCDVVA AEVLTLALLL ALAKRSARDA SERSASMSYL AIASILNVAS SISDIIDIYL
EDIWDVNTDK LEAHDYGGYW RLELLTALVP LAVLGFLPLL PRTREAAATK EDGWFAPWKD
AGHGRTAAFL FVAFWVGDAD PLAGTHAAAA EASSRKPSRF TLKKRPAPEA LHRQTLRALL
AASPATFDAT FTERRLGFAQ GRKRVIQRFA VVLARYASSG RAFVRVTSTT PGVCEASVKP
TDELAAVDGE PVLSPDGASL AALIGGILSG PRPLTFTFAG GARRVAAYDA QERKRSSEGA
DDARARSCRE ACGRAEALLE ECREWSRGGG GDAHLAAAAG RCAAEADAAE ATAGDHGPAR
AWADRARNAA TRAATLSLLR AGDAGALVDA CKRGARDAKA ARRAAEQIDN LDGPLLVAAV
EARCASAACH AGAAGDAAAA LLARAAARIP AADRGDVPPG SKATLCGVDD LDGVAAVVES
YSPESDRYEL RAGDGAVYAV RRNKFALEDA GGADAARGAR LARLAAANHA RVSELLARAR
SRKRRPRARE VAEEVSLEER RADSPTYARF QTDDLRNSEP LSYNSLMSLD DDEKDAAEET
RKDSLMSLDD SKSGRAPSPW SVYEAAFVRR EVAAGRLTDA SLEDMLEPED ADAPPPLPPA
PLLVEEEEAE LLREPLMSPG RSVALSQSSS LHVAASQTRR SPFDDASSDD GGAPPPPPSP
GRLAFRGPSA EDLAAIDPRP DRAASPSAGG FFAPFSEGRP LSSLYSTSEP PSPPIPSAFS
SPVVSGSSAP PSVRGDASVV SCDADGRSPR DAPSPDALAG ALSPTTFSRL TDSFLNLRAS
LAPPPPPSLA LDADVVAAGG AGPPSPKAAR PSEPARSAPG PDADDIGRLV GDDVADMVSK
VKATRANRKK KPKRRRAPSV
//
