ID F0YKU4_AURAN Unreviewed; 2893 AA.
AC F0YKU4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=AURANDRAFT_67345 {ECO:0000313|EMBL:EGB04299.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB04299.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dispatched family.
CC {ECO:0000256|ARBA:ARBA00038046}.
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DR EMBL; GL833153; EGB04299.1; -; Genomic_DNA.
DR RefSeq; XP_009041009.1; XM_009042761.1.
DR EnsemblProtists; EGB04299; EGB04299; AURANDRAFT_67345.
DR GeneID; 20226201; -.
DR KEGG; aaf:AURANDRAFT_67345; -.
DR eggNOG; KOG3664; Eukaryota.
DR InParanoid; F0YKU4; -.
DR OrthoDB; 5404397at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45951:SF3; PROTEIN DISPATCHED; 1.
DR PANTHER; PTHR45951; PROTEIN DISPATCHED-RELATED; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1812..1830
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1837..1854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1866..1885
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1912..1933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1945..1968
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2300..2319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2326..2348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1858..1970
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2893 AA; 322755 MW; E97F908FC2A684AB CRC64;
MFVDSASSDE DGASEGSEYS AAAAADDWFD GSSESDDDSS ASERGSESDS AAGASDDDED
SASQSSSSSG QPAAALTEES IPWAVALASE LPGQQHGSAK RRCLVPRDLY KGLADVIDVL
RAGGPKELNQ QLKELYARGK RLQGQARDNN DAEDRMAHEV YGRVKEANLN MPVLGMEVLE
NVRLLREHTG LHDCEITRLK NVAAYLVDDA MLNRADGTIG NLIELTGLSA TMLRNGADRR
EAFFEQPPDN TETPHRGRVR IPLHDLVSAW KEMHFCELLE LDKDYQASYT KKKFKTDGKN
LVCIKCQKKV LMGTKGDVVK WYQDRHPNSL ISTATLRKLV CPCMRPSSGN DCACPICWEI
VYIIKALRES FRQKGDICDC EACKPGSAWR AAIQSPHALR LALSPCGKET CPGFQLPKEK
EPPEFYMFTC AVEKQPPKGA DKVLPELHRK CTQCTYGYQM VMPKEGKCKR LTLPLTYHSK
QEVNAAPRVD KCFADKFVKV PSTYGEISNK LADKTNKWHY HMWIKQQTKR AQELEIATFD
GERSIVVVTD FANRNKLHGI AQSTSEISPA VGCAVAIVLY NPGEQVDGQE RPVQTDVWRI
FSGAKDCAHY NALLIEEIFV HYSGQEPHKE SKLQLPEGGW GEPRRDRLRP PAMSAIGRAC
SRGAVPGLKK ITVISDGKTS TYKGAPSFGY LYGITEKYDV EIMQMFGAAH HMSGPVDAYG
TWSCNGCYIY GGYNDGAAKH EDTDVQGWAT VDEVNGGIHY DAPNAHSSQL YCVRIKAPWT
PEPKEHPLAR VDSEPDSDDL ACTGKDGKKK MCLPCRNREN QGTILSGEPV APLECDYQHW
CGTPRYVQLL GYRADTEAQK AKEKLRKTQE TREKIAAKKR NLSWHLKLHY PPSKIELASK
SQLRPGEDTL YGSACSRELR HRRPAALKAA TPTKVPSQHT TMKNVLWDMF ETKVTSGCEL
HFFPEHTLPH LHFHHRDAPQ NMRVLKTAGA RAIAHNLIRS STKCTRLQTI GSTNKVKGAT
VRTEWIRPHL EITLRNVTQS GGHYVRRMRR VTVCKLVQEQ VQLTLHRAQL IRPDIIASSG
CARSALWHGV TPRHGAPFRS PRGPERPGRA ELAQRLVGVA LAVGVRVVAV AGLERRVAVA
PVRLEVEAVV QVGAGAAREH RFNGAIDANP SGSRGRRARV VDVEEREGLV LALADMSGQP
MGPGAEPVDA ALRRHVLRHG PTRDVHRIRQ RAVLEAHREL FGLDSELHNE FQRTQSIGAA
HGVTPNGFDV LGVHAEPQRR PQDAAKGRRP KFGGAAQDAV MIPYTTYLGE PSQVAMAART
DFGASVELVQ AQASSKRLSG LGRVALAPDA QRLPNNIVRV SLFAIQALQY MAENEDSIPS
SETLCAKESE DVDMEPSSIE LMENSRDRAQ CKSPGVSILE LACNPCGDTR DEDELESAGH
AIASSYAFPP AEQHKAKTDF RAETENESRS ASEAIRFPKQ SKRASTIVDH HDDRSAISND
VAAGRPLNNL ACIVADRPGF LCFVVLFLCA GAAAALMSVN FAASEPSIYD WSITDDKYTE
RFDMITLAAN DVDKLHVGER RDPTYSWSFL YDANLQGDCE TPYGIFTSRH VQTICETEKF
VLLSQEYLER FCVLAADDSC APAHLSLTFW CGCNKHLYFK NTPARFYGSN ASCRELPQHQ
VSQQANQIPQ EVSRLLLGDP ASYRRVDSWY DRSQEAYRSS NHTCKARSFI YFGTPLAGYS
STGSKESGSQ WDTVIDDLGY KIEKRLWNKY DMKATPAESR YMRAAVKKKL DVLWYSELVL
IKEVLRIADK DVTIFLGAIL VVFLIISCYL RSLPMGWCAT LQILMSMLLA LFFYRCVLGL
RYYTGLHALV IFIALGIGAD DVFVFTDAWR RSWFLDPPDD DRKHLRLRLT YAYSRASGSI
AMTSFTTIAA FLANLASPCM PMVSLGIYAS LCVLFDFILG LSIIPALFSL SHRYRRCFCN
RAEDSPPRDG AASRAVADGY LSLLTWRPDR AAGAGKLSAP TSGTAAGARA VRRGAAVIAS
HLQPPAERQP WFLKNHMFER SIRLMKNDFS LDDIAASPSI SVSFGMKSVK RPNYDPYVPK
KNRGKVTFVD TFDLYLEQSQ KQILNACEVL RDWECDACEG HGDKRLVWKG SVVCFMEEFH
EWHAETYGTD TYILTKSEFD VRLKEFRETT VPLHAMYSSW ENLIGYVDGQ LRYVRIDAKM
AADLYNGVET NKQVLRRANK MLSRIRSFDP HSPLTGDVFH ASQVWLEYKT QRALLRGLRD
GLLITFAAAF SMLLFMTRDI RLSVCAILTV GCVISNTMAF ARLLGWVLDG AVCFMLILVV
GLSLDFALHL CHMYDYAASH LHYKSRVDKT ISAVRSMGSS VTAGAVSTMS AGMVMLACQL
PALNKVGIIM VDGSRQKEAC FAPFLYIATT RLGVGLSRLW RETELSAVIL YLQPGFKIAE
GKLPPYFGPS YRKLESSEST QSERIFDWGF GRPSFQEPDT EAGVLAPTLR SEIGADLRPL
DHNTGLRGYR APSTMLGDEE DLIDPTIQLP PSTLHLEVLQ EMTMPRAVIA TESPEVRGRG
TSRDLLPENT TSDMVSYVWP EKSKETRGPW TWVVTLVTMN GVEIRPARAL ERSLQSGGEN
LRPKRKDIVF SKYCSHGPLA KDIRLCVDPC RQPTCVWCKQ HGIFDYKNRT TFERDSRPEV
ANTWVSDDIH MAKTLAREDV STSMKVIEKT MKQQGMLQPP TKRMFTSLTW VPAKFSRNDR
DIVAAGLWDS CCNRAFIDEH FFKTLCAREL TYGIQQYKDK PDINGVILAR NSKMQIQPSP
DVECMPKVTM VKTGNAINKA EILCRFYFTE QEALQQCTSY LIDHHPPNKP YQIDHDDMQV
ESYSLATRGE SQI
//
