ID F0YNU3_AURAN Unreviewed; 733 AA.
AC F0YNU3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Nudix hydrolase domain-containing protein {ECO:0000259|PROSITE:PS51462};
GN ORFNames=AURANDRAFT_68202 {ECO:0000313|EMBL:EGB03216.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB03216.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; GL833183; EGB03216.1; -; Genomic_DNA.
DR RefSeq; XP_009042094.1; XM_009043846.1.
DR AlphaFoldDB; F0YNU3; -.
DR EnsemblProtists; EGB03216; EGB03216; AURANDRAFT_68202.
DR GeneID; 20226665; -.
DR KEGG; aaf:AURANDRAFT_68202; -.
DR eggNOG; ENOG502S0KP; Eukaryota.
DR InParanoid; F0YNU3; -.
DR OrthoDB; 37618at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR CDD; cd02883; Nudix_Hydrolase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR PANTHER; PTHR43046:SF13; NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT DOMAIN 30..177
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
FT REGION 293..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..338
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..374
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 79656 MW; 90D54BCEDAE1D5D2 CRC64;
MAPLRHFITG DFEKRTVFLP DKEYGLALDA LVKGCADVLI TSGAGPSLRI LLGKRRVEPQ
PDWWFVGGRT RPGDTPAEGA ARNVKRELGL ALDPARFAAV GTYSFVWRLR AQAPATNGTA
DVSTVFELHL ADDEAADLSP ARFDAEEYAD AAWTRPDAVL AGDYHPALQQ AVRDLLARRA
YGALRDAAAD ASAGAGAVAA AATAYVAWRE SAPTDGCKVR FEDGAYVFVD PATGAAAPRP
ATGAAYWARW KLLADARGAA APRWGLAVLG LAASTRWQPA RFTVTRQHCA TMKGTMASSS
PEETEARKAN KAAGDAAFAD DDDDDDDDDD DDDDDEQMER APMPWPTPRP TPAPRPATAP
PTHRPTPRPA PRPAGPEEEC FALQATHGVK PAMTWGTLDR NPSSFRRWKE LGCGGVVERA
ANAAADAAAD AAREVCPKSA DPKPLIAVCS GTTTRQKGGW ITPRPGHLED LAAFQYLLPS
FKRTAECGFR YLVVLAYDVG DQFWDRGDGV ARARAWFEAS IATPLAAANM DVELRFVKVD
NAVKKPGPVF AAMTRAAYAA WKADYIYRVN DDTEFKTKWA RPFVNALASM GNVGAVGPLC
RQGNTAILTH DFTHRTHMDI FDGAYYPPEL SDWWMDDWIT GVYGSLRTLM GDRVEVIHHT
GKHGQRYAVD FAHEKLVKQL IAAGHARVES FVAARDAPPP GNPPPSFRRF RLKSHGGFQR
RRRLRAAGRD SVS
//
