ID   F0YUU4_9CLOT            Unreviewed;       728 AA.
AC   F0YUU4;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN   ORFNames=HMPREF0240_00912 {ECO:0000313|EMBL:EGB94664.1};
OS   Clostridium sp. D5.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=556261 {ECO:0000313|EMBL:EGB94664.1, ECO:0000313|Proteomes:UP000003978};
RN   [1] {ECO:0000313|EMBL:EGB94664.1, ECO:0000313|Proteomes:UP000003978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D5 {ECO:0000313|EMBL:EGB94664.1,
RC   ECO:0000313|Proteomes:UP000003978};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA   Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA   Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA   Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium sp. D5.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL870809; EGB94664.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0YUU4; -.
DR   eggNOG; COG1305; Bacteria.
DR   HOGENOM; CLU_016605_0_0_9; -.
DR   Proteomes; UP000003978; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003978};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        73..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        98..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        583..611
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          461..536
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          552..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..576
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   728 AA;  82541 MW;  7F87496D6F71AAC7 CRC64;
     MILAGTGRGK ARFLKIAAWC GLLAVTILLF GDIWNDGIHI LYNHAVDVLG KQYPYLLPVY
     HVAAEGTMET VCMYAALAWM SGMLAVLGQY LVRTGNRLLL GIQIVFILLV QMAAGIAPEL
     LWNIGSFLCL LAVWIRGHGE MVPAGKQRLA SLQVFALVAA GSALLLFGGS IVLGKTTVTE
     NDLFAGWKET WKSMIEESRY SGDAEVLPEG RFTGLGSLET ENKPVLEVTM TKPESYYLRG
     YTGSQYTGTG WTDIPSEKLW EGRDLFYWLH QGGFYGQECL GDAAVALDEE TAAEERNTVV
     VRNLAGSSKY CYVPYELQSV KEADLQTRMD AQKIGDAGLI AGGWNGDREY VYQALSNQIT
     KYPVYDARLL DKKNLTEAGK AYKRNEEFYN EFVYATYLDI PFELTSALHE LIDTGETEQG
     EKHVDYAEAK QNILYVLTAD YTDTKKLDGS WNGSDFIQEF LNYSKKGYSV HFASAAAMMF
     RYYGIPSRYV EGYLVTPEDV KAMTAGEPYI LDDTHAHAWV EYYQDGVGWL PFEVTPSYIG
     TMDKAEDFQD ISGLSGQGSE NQPDEPEEEE EEQKKEEEDE IDWLLILEIV LITGICLMLL
     IMLVFLIWVL LQRHKSRKAK KLFGSADRRL AIRALFEYSM NILSVAGLDI RNTSLYDYRE
     PVGDMFDEET AAEYEEIVRI RQEAVYSEHE ITEEQREIQE SFKNKIWIRI YKNGNIIQKF
     RLKYIYFL
//