ID F0YXS5_9CLOT Unreviewed; 461 AA.
AC F0YXS5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=MATE efflux family protein {ECO:0000313|EMBL:EGB93763.1};
GN ORFNames=HMPREF0240_01640 {ECO:0000313|EMBL:EGB93763.1};
OS Clostridium sp. D5.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=556261 {ECO:0000313|EMBL:EGB93763.1, ECO:0000313|Proteomes:UP000003978};
RN [1] {ECO:0000313|EMBL:EGB93763.1, ECO:0000313|Proteomes:UP000003978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D5 {ECO:0000313|EMBL:EGB93763.1,
RC ECO:0000313|Proteomes:UP000003978};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium sp. D5.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL870810; EGB93763.1; -; Genomic_DNA.
DR RefSeq; WP_009003007.1; NZ_GL870810.1.
DR AlphaFoldDB; F0YXS5; -.
DR eggNOG; COG0534; Bacteria.
DR HOGENOM; CLU_012893_5_1_9; -.
DR OrthoDB; 9780160at2; -.
DR Proteomes; UP000003978; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13134; MATE_like_8; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR InterPro; IPR047135; YsiQ.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR PANTHER; PTHR42925:SF2; NA+ DRIVEN MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000003978};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 461 AA; 50625 MW; 232BC671A2DB6A20 CRC64;
MTLFKRKDDG LDIDWGKFYR SVFALVIPMA LQNLINVGVT AADVIMLGKV GEKALSGASL
AGQVQYIMVL FLFGLTSGAT VLTAQYWGKG DRKTIEKILG LGMKAAIIVT AIFTVAALLI
PELLMRIFTN DPAVISEGVK YLRIVAFSYV FMGITQVYLY IMRSVERVVV ATVVYLISLL
CNVVLNAIFI FGLLGCPAMG IQGAALGTLA ARFVELVLVF GYARLFNRDI KFRFRYLLRT
EKLLLKDFLR YAMPVVMNEV MWGLGTAANT AILGHMGSAA VAANSVAQVA RQLATVVAFG
LSSATAIYLG KTIGEKKFEH AKAYAHRFLL LSVVMGAVGG VIILASAPIT AAVLSLTPAA
KSYLKFMFFV MSYFVIAQSF NTTMVVGTFR SGGDTRFGLI MDVSTMWGCS ILFGFLAAFV
FHWGVPVVYI ILMSDELIKV PITWIRYRSY KWLKDVTREI E
//
