ID   F0YZW8_9CLOT            Unreviewed;       766 AA.
AC   F0YZW8;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE            EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN   ORFNames=HMPREF0240_02397 {ECO:0000313|EMBL:EGB92389.1};
OS   Clostridium sp. D5.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=556261 {ECO:0000313|EMBL:EGB92389.1, ECO:0000313|Proteomes:UP000003978};
RN   [1] {ECO:0000313|EMBL:EGB92389.1, ECO:0000313|Proteomes:UP000003978}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D5 {ECO:0000313|EMBL:EGB92389.1,
RC   ECO:0000313|Proteomes:UP000003978};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA   Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA   Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA   Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA   Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA   Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium sp. D5.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC         with release of beta-D-glucose.; EC=3.2.1.21;
CC         Evidence={ECO:0000256|ARBA:ARBA00000448};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL870813; EGB92389.1; -; Genomic_DNA.
DR   RefSeq; WP_009003700.1; NZ_GL870813.1.
DR   AlphaFoldDB; F0YZW8; -.
DR   eggNOG; COG1472; Bacteria.
DR   HOGENOM; CLU_004542_5_1_9; -.
DR   OrthoDB; 9805821at2; -.
DR   Proteomes; UP000003978; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR   Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR026891; Fn3-like.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR   PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR   Pfam; PF14310; Fn3-like; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   SMART; SM01217; Fn3_like; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003978}.
FT   DOMAIN          684..753
FT                   /note="Fibronectin type III-like"
FT                   /evidence="ECO:0000259|SMART:SM01217"
SQ   SEQUENCE   766 AA;  84333 MW;  DF6022112DFE4DF0 CRC64;
     MNTTKYMNTS LSVGERAQDL LSRMTLKEKI GQMNQKMHGW NAYKVEGETV ELTEAFAEEV
     AFGDGVGAIY GVFRADGWNS HLTSGIKVRD SVRVANTIQR YIRENTRLGI PVFLSEECPH
     GHEALQATTF PTNIGIGASW NTELYEKVCN IIARELRARG GHLGLISALD IAMDPRWGRT
     EECYSEDPFL AAAFCEKAVL GMQGDKDALT QPDRVISVLK HFCAQGATIG GHNGKATNIG
     PRELFEIHLP GMKKGAKAGA LGCMAAYNDI DGVPCHINRS LLTGILREQF GFTGFVMSDG
     RGVDRAKNIT GSYESACAAA VHAGVDLNLW NECFLKLENA VRKNPLLEKD IDAAVLRILE
     AKFRMGLFEN PYVEETPALL NIGSKEAKET ALEIARESVV LLENKGDVLP LGKEIKRIAV
     IGPNGDSVYN QLGDYTQWKE EGEVVTVLQG LRKQAPSGVT IEFATGCGIR DVSKDGFPSA
     ISLAEDADAV VMVLGGSSTR EPGMTFEDNG AVFMNAFTKE LNCGEAVDLA ELRLGGVQED
     LAKEIKKFGK PLIVVLIEGR PHAVSWMKEN ADALLCAWYP GERGGDAVGE ILFGRTNPSG
     RLPVSIPKSS AQLPVYYNRK DETDYIDESA KPLYPFGYGQ SYTEFVCGDF KLNTQRLSLK
     ELEQGKRFEM TCSITNKGGR QGKEVLQLYI YDMESCITRR VKELKDFAKV SLEKGEERQV
     RLSVGDEELR IYDYDMNFVL EKGHVRLMLG KSSADILYDT IVEIVS
//