ID F0ZCB0_DICPU Unreviewed; 1122 AA.
AC F0ZCB0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Structural maintenance of chromosomes protein 5 {ECO:0000256|ARBA:ARBA00018687};
GN ORFNames=DICPUDRAFT_148904 {ECO:0000313|EMBL:EGC38414.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC38414.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC5 subfamily.
CC {ECO:0000256|ARBA:ARBA00010171}.
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DR EMBL; GL870977; EGC38414.1; -; Genomic_DNA.
DR RefSeq; XP_003285075.1; XM_003285027.1.
DR AlphaFoldDB; F0ZCB0; -.
DR STRING; 5786.F0ZCB0; -.
DR EnsemblProtists; EGC38414; EGC38414; DICPUDRAFT_148904.
DR GeneID; 10502139; -.
DR KEGG; dpp:DICPUDRAFT_148904; -.
DR eggNOG; KOG0979; Eukaryota.
DR InParanoid; F0ZCB0; -.
DR OMA; RFWTSQP; -.
DR OrthoDB; 232016at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0030915; C:Smc5-Smc6 complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR027131; SMC5.
DR PANTHER; PTHR45916; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR PANTHER; PTHR45916:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5; 1.
DR Pfam; PF02463; SMC_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064}.
FT DOMAIN 70..1047
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 432..477
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 662..742
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 801..828
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 879..913
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..64
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1122 AA; 129711 MW; CDE72B8EC3BEF6FA CRC64;
MSRLNNNLKI PKKHQLDEIS DDDSDEGDNR KNFNLQRKKG RSENQPTQNI TTPTPDNNDD
NQEGYVKGSI VRIKLNNFVT YSDVEFRPGP RLNVVIGPNG SGKSSIVCAI ALGLGGSPNL
LGRQKQLGDF VKRGTMSGFV EIELFNPDGE NFIIKRDLKK EGNSGDFKLN GKNITKADLL
ARIKELNIQV ENLCQFLPQD KVVGFASMSP TELLLETEKA IGVDNMYENH QELIKLRSDS
SKDNQNIDSQ RQQLEEKKDL NQQLERDVER FREREKILEE IESYKKKKAW AIYDNLKRQA
ENLKEEEERE QKNFKEASNE LIPLRASIIA QEESLKKTRE EAEKLDRKIL LLNREVGVCS
DGAEKVQVQI DSFVKELDGL NERQQKRNRD IEATQTSITQ LKSEMDQLPP EDQDKARIEQ
INKENRENNT KTNEVQLELQ QLHQQYQRVQ MDCQKIEKEI ANLNDGHRQK LEKLKSEGDV
FQAYTWIQNN KAKFEKPVYG PVLMEINVVN PEYASYLETS LSWNLLSSFI FQTQKDRELF
HSSLTDSNRK LRLNSILINN IPPVDRSYDI EDYRQYGAVD YLDNLYEANP IVKAAVNDSI
PIFKTLVFNK NAIGKEDILL KSILSFQTPE SSYLTSFSRY GDKKSITRVI KIKKAHWLTG
INKALKLELE NSYKEISAKR EELKSKGTEL KQKEKEIQVA SKELLGERAA LNLNIEKRRK
LVNRINVQIN ALEDLKNEEN IEEEGKKIKS KIYLGYQKKI QLLQKAIGFT DELNKSCGAK
DHATISSSRF EAKLHSEKDH LEKETIRVNQ IKERMQQLNK DFKNTYRECQ LKHQEAQKIA
PYTPDLKTQF TKLKGSSLGE IDDEINVLDA KASFIVSSNS RVIEEYEGRK KEIEELEERL
SNYEQTAANN NTRLITLKKK WLEPIQEYIN QINQRFSLFF SEIGCEGKVI LGNDPKDEND
FSKYCINLQV RFRDETSLKN LNAQLQSGGE RSVSTMLFLI SLQNLTKCPF RVVDEINQGM
DPKNERMVFE QIVKTVSKPD LPQYFLITPK LLHNLPYSRE TTVLCVFTGP WFISQQEWDE
FLYSYLRGAK KNNRTTTTIT TTTTLNSDSS SEEEEEEEEE ED
//
