ID F0ZF14_DICPU Unreviewed; 338 AA.
AC F0ZF14;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=DICPUDRAFT_149932 {ECO:0000313|EMBL:EGC37441.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC37441.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- FUNCTION: Probable adapter protein and signal transducer that links
CC members of the tumor necrosis factor receptor family to different
CC signaling pathways by association with the receptor cytoplasmic domain
CC and kinases. {ECO:0000256|ARBA:ARBA00003051}.
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DR EMBL; GL870999; EGC37441.1; -; Genomic_DNA.
DR RefSeq; XP_003286005.1; XM_003285957.1.
DR AlphaFoldDB; F0ZF14; -.
DR STRING; 5786.F0ZF14; -.
DR EnsemblProtists; EGC37441; EGC37441; DICPUDRAFT_149932.
DR GeneID; 10499801; -.
DR KEGG; dpp:DICPUDRAFT_149932; -.
DR eggNOG; ENOG502RBHI; Eukaryota.
DR InParanoid; F0ZF14; -.
DR OrthoDB; 222086at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10131:SF65; RING FINGER PROTEIN DG17-RELATED; 1.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 49..92
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 338 AA; 39706 MW; D09A75B95508B151 CRC64;
MAKKSIEKKK PVQTTPQQKE EDGSINLKLN YTIDEIVVDF ESFDKKYECN VCCNYILDTN
IRVARQCPKG HYVCMECWER ILKSKKECPH CRTKVESVPA LSRNIFLENE FNELLVHCPF
SKEGLVKNGL SFNITTSTND NIKINKICDC KVKFKDLDNH LRNKCHRIIK CCCGAYFKKE
NHPDHIKQCP ESKISCENCL KPISKSLYEN HKTECSEFFI GQIKALQKCN FPDCNIELPM
YQMGKHMESH VNSLYTMIKD LSIRIDENKL DHQKFPDEYS YQNEEKYLQI VKENKILREK
IENNEMVGVW TIQDYRISNF ITSKSFNMSD LRFKVKLG
//
