ID F0ZL21_DICPU Unreviewed; 291 AA.
AC F0ZL21;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Hydroxyacylglutathione hydrolase {ECO:0000313|EMBL:EGC35363.1};
GN ORFNames=DICPUDRAFT_55252 {ECO:0000313|EMBL:EGC35363.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC35363.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
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DR EMBL; GL871062; EGC35363.1; -; Genomic_DNA.
DR RefSeq; XP_003288101.1; XM_003288053.1.
DR AlphaFoldDB; F0ZL21; -.
DR STRING; 5786.F0ZL21; -.
DR EnsemblProtists; EGC35363; EGC35363; DICPUDRAFT_55252.
DR GeneID; 10501537; -.
DR KEGG; dpp:DICPUDRAFT_55252; -.
DR eggNOG; KOG0814; Eukaryota.
DR InParanoid; F0ZL21; -.
DR OMA; DWILETH; -.
DR OrthoDB; 1350815at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050313; F:sulfur dioxygenase activity; IBA:GO_Central.
DR GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR GO; GO:0070813; P:hydrogen sulfide metabolic process; IBA:GO_Central.
DR CDD; cd07724; POD-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR044528; POD-like_MBL-fold.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43084:SF11; GLYOXYLASE B2; 1.
DR PANTHER; PTHR43084; PERSULFIDE DIOXYGENASE ETHE1; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGC35363.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064}.
FT DOMAIN 15..207
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 291 AA; 32483 MW; 09471E7E85B46C0D CRC64;
MNKAKIEIFP ELESATGQVL IIDESTKKCA ILDSVLNYAQ ASGKTSTTDA DKIVKYIKEN
QLEPEWILES HIHADHLSGA HYLKSIYPQA KTAIGEGAKV VQKTFKTIYN LEHSFPVDGS
QFDHLFKDGE DFKVGTLNVK VIATPGHTPA CVSYYVENDC VFVGDTMFLP DVGTARCDFP
NGSAETLYNS MKKILALPED VKVYVCHDYP PAGRTITFET TIGEQRKTNK HIKDSVSKEE
FIKMRTERDA TLKAPQLLLP SIQVNIRAGE LPPKEDNGIS YIKIPLNYLK Q
//
