ID F0ZN56_DICPU Unreviewed; 1277 AA.
AC F0ZN56;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN ORFNames=DICPUDRAFT_34701 {ECO:0000313|EMBL:EGC34621.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC34621.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; GL871090; EGC34621.1; -; Genomic_DNA.
DR RefSeq; XP_003288846.1; XM_003288798.1.
DR AlphaFoldDB; F0ZN56; -.
DR STRING; 5786.F0ZN56; -.
DR EnsemblProtists; EGC34621; EGC34621; DICPUDRAFT_34701.
DR GeneID; 10499465; -.
DR KEGG; dpp:DICPUDRAFT_34701; -.
DR eggNOG; KOG1217; Eukaryota.
DR InParanoid; F0ZN56; -.
DR OMA; SAICNNQ; -.
DR OrthoDB; 5489847at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 5.
DR CDD; cd00603; IPT_PCSR; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 14.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR PANTHER; PTHR24034; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24034:SF166; VACUOLAR-SORTING RECEPTOR 1; 1.
DR Pfam; PF12662; cEGF; 3.
DR Pfam; PF07645; EGF_CA; 4.
DR Pfam; PF14670; FXa_inhibition; 6.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00181; EGF; 15.
DR SMART; SM00179; EGF_CA; 14.
DR SUPFAM; SSF81296; E set domains; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 5.
DR PROSITE; PS00010; ASX_HYDROXYL; 12.
DR PROSITE; PS01186; EGF_2; 11.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022530};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1236..1258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..153
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 212..252
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 628..670
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 671..713
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EGC34621.1"
SQ SEQUENCE 1277 AA; 138526 MW; A2BA13C3CE61E527 CRC64;
NIVNNKIDYY QCEEVTWIVD QSYYEYYDSV GGCGKDGYTV IPITFSTTNR FLVVLSCATT
GGYWYTAESS PTNQATAATK ATCKGTMKTD YSLEIYSAVC PVGYTGTAPN CVDVNECSTN
NGGCAQTCTN TPGSFACSCA AGYTLNPDGK GCTDINECAT SNGGCAQTCT NSPGSFACSC
DSGYTLNADK KGCTGYLKLN IHFFFIIKTK IDINECATSN GGCAHTCTNS IGSFVCSCDA
GYTLNSDKKG CTDINECSTN NGGCAQTCTN SPGSFACSCG SGYTLNTDKK GCTDIDECKL
NTAGCSDMCT NTIGSFVCSC PSGYYLAADK KTCLDINECL TTPTICGSAI CNNQIGSYNC
SCENGYELTP NNQIAFTCED IDECDRGISG CSQLCENTIG SFLCSCESGY TLNADKKGCT
DINECITTPT ICGSAICNNQ IGSYNCSCEN GYELTPNNEN SYTCEDIDEC DRGISGCSQL
CENNIGSFSC SCESGYTLDA DKKGCTDIDE CIDGGGCEQI CNNLMGSFEC LCDPGYSLDD
DKKGCTDIDE CVVGSSGCAQ NCKNLIGSFE CSCDSGFTLN DDKKGCTDID ECIDGGGCSQ
YCHNSPGSYS CSCDSGYVLD SNNKICLDIN ECLDGSNKCI GVSVCKNTIG SYDCQCPNGF
VSTSDKLGCE DIDECSSIEL NKCANNTNCL NTFGDYNCPC IPYFSRFDKY NCVPKPIISN
FYQKPTKVNI FQVEGYNFIA SHETKTLINS QLECTYLSGN ENSFECFTSE NTEVRGNVTV
ECNQLVSDSF NYIGAPFLTQ YVGTPSTMGG DIITLFGRNL PTGNIQLLVN SNPQNITIVD
EDYIEFQSSQ GSGKNNLIRL SNETATNTDM MFIEFAHPTI NNASEVSGET GGVLTIQGDN
FGTNPSLIRV DIGKFNCFDI KVTVPHKELT CLLKPQTTYF YTQLIDLEVD SLPVDNDYYF
TFSFLKETLC PSECSGNGYC SDFGCVCNKN FTGISCNETV VEINPHPPII DIPSIEIDND
DNKAFGYNVS IIRIEELNIE DVVITSYSLL EEKWSFKNNS ELNNQWIFNI TLNNKCYLEA
TFEYFKLSRE ITFAANTFVV PAESLKLTFI TKDWPFKSKL NSLRIVVSTQ TINLGGSSCS
IDKPVTSTFN QHLWTTTKNE ESGMTARFIS AAEIDERPIT PKIESLESSR TTSIVGISVP
YFRNKSVIDP DFSMLLNVNK QKTGNCQKEN KVDWKIATGT AIGASAAVCL IAAAGYVINR
KKKEKELSEI MNKRQRS
//
