ID F0ZSC4_DICPU Unreviewed; 579 AA.
AC F0ZSC4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Phosphoprotein phosphatase A {ECO:0000313|EMBL:EGC33157.1};
GN ORFNames=DICPUDRAFT_98650 {ECO:0000313|EMBL:EGC33157.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC33157.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family.
CC {ECO:0000256|ARBA:ARBA00038332}.
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DR EMBL; GL871155; EGC33157.1; -; Genomic_DNA.
DR RefSeq; XP_003290313.1; XM_003290265.1.
DR AlphaFoldDB; F0ZSC4; -.
DR STRING; 5786.F0ZSC4; -.
DR EnsemblProtists; EGC33157; EGC33157; DICPUDRAFT_98650.
DR GeneID; 10504677; -.
DR KEGG; dpp:DICPUDRAFT_98650; -.
DR eggNOG; KOG0211; Eukaryota.
DR InParanoid; F0ZSC4; -.
DR OMA; NRVEAMQ; -.
DR OrthoDB; 759105at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblProtists.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblProtists.
DR GO; GO:0005886; C:plasma membrane; IEA:EnsemblProtists.
DR GO; GO:0000159; C:protein phosphatase type 2A complex; IBA:GO_Central.
DR GO; GO:1905742; C:Ras guanyl-nucleotide exchange factor complex; IEA:EnsemblProtists.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:EnsemblProtists.
DR GO; GO:0019888; F:protein phosphatase regulator activity; IBA:GO_Central.
DR GO; GO:0005198; F:structural molecule activity; IEA:EnsemblProtists.
DR GO; GO:0031034; P:myosin filament assembly; IEA:EnsemblProtists.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR PANTHER; PTHR10648:SF4; PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED; 1.
DR PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR Pfam; PF02985; HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 10.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 8..46
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 86..124
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 163..201
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 202..239
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 241..279
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 280..318
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 319..357
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 358..396
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 397..435
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 514..552
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 579 AA; 64587 MW; 660514D67A45200B CRC64;
MESDEYHPIV ILIDELKNDD MQLRLNSIRK LQSIAKALGP ERTRTELIPY LQDSVLEDED
EVLVALSEEL GNLIEFVGGP EHAVCLLPPL QILAGAEELV VREKAVESLC KIAKEIPNQA
FEDSFIPLLF TLSKADWFTS RTSACGLFTV SYPRANAEMK KSLRKTFAGL CHDDTPMVKR
AAATNLGNFA KQIEKDAVKQ EILPLFQSLS TDEQDSVRLL GVENCALLGS MLTPEENAQV
ILPTIKSCSL DKSWRVRYMV ARLLKELCES MGPEITKNEL VGAFVKLLKD TEAEVRTEAA
LRIADVCSLL PKEISIKTIL PCVKDLVSDS SQHVRAALAQ VIMSLAPVFG KEDTVAHLLE
LFLQLLKDDF PDVRLNIISK LDQVSKVIGI EMLAQSLLPA IVELAEDHQW RVRLAIIDYI
PLLASQLGVE FFDEKLGNLC MTWLGDSVFS IREAATNNLR KLTEVFGVEW AKNNIIPKVL
SLHSHPNYLY RMTTLFSIST LSTVVGGDLI SQAMVPLLAK MVSDKVPNIR FNVAKTFQTI
IPLLDSTVVQ SRVKPLLLKL QEDTDKDVKF YSMQALNLC
//
