ID F0ZST5_DICPU Unreviewed; 452 AA.
AC F0ZST5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=DICPUDRAFT_155001 {ECO:0000313|EMBL:EGC33011.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC33011.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; GL871163; EGC33011.1; -; Genomic_DNA.
DR RefSeq; XP_003290481.1; XM_003290433.1.
DR AlphaFoldDB; F0ZST5; -.
DR STRING; 5786.F0ZST5; -.
DR EnsemblProtists; EGC33011; EGC33011; DICPUDRAFT_155001.
DR GeneID; 10507877; -.
DR KEGG; dpp:DICPUDRAFT_155001; -.
DR eggNOG; KOG0166; Eukaryota.
DR InParanoid; F0ZST5; -.
DR OMA; NTDEDIC; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0006607; P:NLS-bearing protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF75; IMPORTIN SUBUNIT ALPHA-B; 1.
DR Pfam; PF00514; Arm; 4.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT REPEAT 96..124
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 452 AA; 50331 MW; F7A038641540B77E CRC64;
MSIEEDNTPG YTLKDSLADI KSNDRDKILK GVVYVRKALS VESKPPIQQT IDLGMGTALI
RLLGSGDPSI QLEAAWALTN IASGTNAQSK HLIDLGIIPP LVELLKSEHY DVVDQAVWAL
GNIAGNDVSC RNLVLQTDTI KLILEIITRG PTVKLTILRN ICWTLQNLCR GKPQPPFSTV
SILIPYFERI LINTDEDICT DVCWSMSWIS DTTNDNLNFI LSYESLVEKM IEFLYHPSLS
IQVPALRFVG NILTGDDNQT QKILNYRGVL PHFVGLLNHK KKNVRKEASW AISNAAAGNS
IQIQALIDFN VFPSLISLLS KEKDIDVKKE AIWALCNGIA GGTTQQILYF VNLNSIKHLC
DLLRIDTLDN IVIGTILDSI DRILATGLSV APYGPDSNPM LSMFQDAGFL DIACYLENFT
DENVDKFELI GEKYFFQEDE VMVLDELENL NI
//
