ID F0ZT33_DICPU Unreviewed; 781 AA.
AC F0ZT33;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=J domain-containing protein {ECO:0000259|PROSITE:PS50076};
GN ORFNames=DICPUDRAFT_155106 {ECO:0000313|EMBL:EGC32897.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC32897.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; GL871168; EGC32897.1; -; Genomic_DNA.
DR RefSeq; XP_003290582.1; XM_003290534.1.
DR AlphaFoldDB; F0ZT33; -.
DR STRING; 5786.F0ZT33; -.
DR EnsemblProtists; EGC32897; EGC32897; DICPUDRAFT_155106.
DR GeneID; 10508047; -.
DR KEGG; dpp:DICPUDRAFT_155106; -.
DR eggNOG; KOG0721; Eukaryota.
DR eggNOG; KOG0951; Eukaryota.
DR InParanoid; F0ZT33; -.
DR OMA; TIENCMH; -.
DR OrthoDB; 1605at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0031207; C:Sec62/Sec63 complex; IBA:GO_Central.
DR GO; GO:0008320; F:protein transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006620; P:post-translational protein targeting to endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IBA:GO_Central.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF02889; Sec63; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..177
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 481..584
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..781
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 528..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..576
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..695
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 696..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..736
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 781 AA; 88602 MW; 57C0AF7EB7B7E353 CRC64;
MKDSPPNYQK ETQATDDYKD IEFLQWLSFF LLIVLIPSTI WLWKKFHPKP TPKQFDCTCE
GCEKKSNEKI NIEKAEMKST LNKVKLYSVV LLWLLFAGLM FIVVTSKHEV VEPYNPYKIL
NIEVGASESE IKTAYRQLSK IYHPDKNPDK EDLYMEVSKA YKTLTDIATR EKWEKYGNPE
GPQRMSVGIA LPSWLINKNN SPVVLTAYLL LLVVALPTAV FYWNKSTTSK LLAPIEQQTL
ALYYHVIDAQ TRLKAMIEIL AASTEYKSAL PDRKSDEENL KVLYQKIPNE YKVKTPRFGA
AYIVKGTILL YAHITRINSK DMAPTLKEDL QHILKTYRHY LTGAFQITRE KRQLAGLVEI
CRMSQCIMQS AWEDQSLKQL PHIDNVLLQS LKSSGYSEIS KFKNIDKEKR KELLAKGSLN
DRQIKDVENI LEKIPCQVGV KYKISSDSPT LLASSVCILE IEFTDQIALK KQKQEDALAA
ASTKKPAAAS IKGGARKRVV NKKQTGADKG DKAIEDKSDD EEEQQEESSP KEEKKPKKEK
KQKEKKLDED GNEIEDEEND DSDSDFDSEY SDSDDDDTWE ATPKKSLINP AKELYHTPFT
FDDKPVSFWV ILGNRSKNEL VALGKTESFA PGQTLKIPFL SSAEIGKCNY TLYVLCDGYI
GCDIEQEISI NLEKNPRPII VQQPNLPPQQ PPPAAKEQPT AQQKPKQQEQ KPVAAVQQEQ
PPAVQPQPPA NPLSPQPKPL TQKQINQQQK QMKKQMKAQA SSSSSSPPEK EKAKIISEDS
E
//
