ID F0ZY15_DICPU Unreviewed; 381 AA.
AC F0ZY15;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=DICPUDRAFT_99295 {ECO:0000313|EMBL:EGC31161.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC31161.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 5 family.
CC {ECO:0000256|ARBA:ARBA00008360}.
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DR EMBL; GL871272; EGC31161.1; -; Genomic_DNA.
DR RefSeq; XP_003292308.1; XM_003292260.1.
DR AlphaFoldDB; F0ZY15; -.
DR STRING; 5786.F0ZY15; -.
DR EnsemblProtists; EGC31161; EGC31161; DICPUDRAFT_99295.
DR GeneID; 10507956; -.
DR KEGG; dpp:DICPUDRAFT_99295; -.
DR eggNOG; ENOG502RYGP; Eukaryota.
DR InParanoid; F0ZY15; -.
DR OMA; IACFCAT; -.
DR OrthoDB; 9980at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0030552; F:cAMP binding; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IBA:GO_Central.
DR GO; GO:0007189; P:adenylate cyclase-activating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd14940; 7tmE_cAMP_R_Slime_mold; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR022343; GCR1-cAMP_receptor.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000848; GPCR_cAMP.
DR PANTHER; PTHR23112:SF23; CYCLIC AMP RECEPTOR 1-RELATED; 1.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR Pfam; PF05462; Dicty_CAR; 1.
DR PRINTS; PR02001; GCR1CAMPR.
DR PRINTS; PR00247; GPCRCAMP.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..261
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 292..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 332..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 381 AA; 42576 MW; 0A1899A90EA39BB8 CRC64;
MGLLTGVPAN DANLVLLLFA DFTSMLGCLA VLVGFWRLKL LRNHVTKVIA CFCATSFCKD
FPSTVLTLTN TAKNGGFPCY LYAIVITYGS FACWLWTLCL AISIYMLIVK REPEPERFEK
YYYMLCWGLP LISAIIMLAK DTVEFTGAWC WIGNSYTGYR FGLFYGPFLG IWAISAILVG
LTSRYTYVVI HNGVSDNKEK HLTYQFKLIN YIIVFLVCWM FAVVNRILNG LDKYPPAITC
LHTYLSVSHG FWASVTFIYN NPLMWRYFGA KILSIFTFFG YFTDVQKKLE KNKNNNNPSP
YSSSRGTSGK TGGTEVELPN YSDMEQCSLE GVNHAQNNND NNYGLPNDAG CSTSSSSSSS
DENDKGKGIQ ISSSTNGNGN N
//
