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Database: UniProt
Entry: F1AWZ6_ORFV
LinkDB: F1AWZ6_ORFV
Original site: F1AWZ6_ORFV 
ID   F1AWZ6_ORFV             Unreviewed;        70 AA.
AC   F1AWZ6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   12-AUG-2020, entry version 21.
DE   SubName: Full=B24R {ECO:0000313|EMBL:ADY76776.1};
OS   Orf virus (ORFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Parapoxvirus.
OX   NCBI_TaxID=10258 {ECO:0000313|EMBL:ADY76776.1, ECO:0000313|Proteomes:UP000103309};
OH   NCBI_TaxID=9925; Capra hircus (Goat).
OH   NCBI_TaxID=9606; Homo sapiens (Human).
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1] {ECO:0000313|EMBL:ADY76776.1, ECO:0000313|Proteomes:UP000103309}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D1701 {ECO:0000313|EMBL:ADY76776.1};
RA   McGuire M.J., Sykes K.F., Johnston S.A.;
RT   "Novel immune-modulators identified by a rapid, functional screen of the
RT   Parapox virus genome.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Late protein which probably plays a role in virus entry into
CC       the host cell. {ECO:0000256|ARBA:ARBA00004101}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Virion membrane
CC       {ECO:0000256|ARBA:ARBA00004381}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004381}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae I2 family.
CC       {ECO:0000256|ARBA:ARBA00007048}.
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DR   EMBL; HM133903; ADY76776.1; -; Genomic_DNA.
DR   Proteomes; UP000103309; Genome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR009175; Poxvirus_I2.
DR   Pfam; PF12575; Pox_EPC_I2-L1; 1.
DR   PIRSF; PIRSF003766; VAC_I2L; 1.
PE   3: Inferred from homology;
KW   Late protein {ECO:0000256|ARBA:ARBA00022921};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Viral penetration into host cytoplasm {ECO:0000256|ARBA:ARBA00022595};
KW   Virion {ECO:0000256|ARBA:ARBA00022844};
KW   Virus entry into host cell {ECO:0000256|ARBA:ARBA00022595}.
FT   TRANSMEM        48..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   70 AA;  7629 MW;  8E959CE23C058793 CRC64;
     MDKLYTGVFG SFLSNSDEDF DEFLNIVRSV LTEKPACDKP KGAPGTTVFL IGLIAAAMGV
     LLCFHYLKLV
//
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