ID F1LWL9_RAT Unreviewed; 116 AA.
AC F1LWL9; F1LVJ7;
DT 22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2015, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Developmental pluripotency associated 5 {ECO:0000313|Ensembl:ENSRNOP00000000215.3, ECO:0000313|Ensembl:ENSRNOP00000041925.4};
GN Name=Dppa5 {ECO:0000313|RGD:1305838};
GN Synonyms=Dppa5al1 {ECO:0000313|RGD:1564306}, Dppa5l1
GN {ECO:0000313|RGD:1559995}, RGD1559995 {ECO:0000313|RGD:1559995},
GN RGD1564306 {ECO:0000313|RGD:1564306};
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000041925.4, ECO:0000313|Proteomes:UP000002494};
RN [1] {ECO:0000313|Ensembl:ENSRNOP00000041925.4, ECO:0000313|Proteomes:UP000002494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000041925.4,
RC ECO:0000313|Proteomes:UP000002494};
RX PubMed=15057822; DOI=10.1038/nature02426;
RG Rat Genome Sequencing Project Consortium;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2] {ECO:0000313|Ensembl:ENSRNOP00000041925.4}
RP IDENTIFICATION.
RC STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000041925.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the KHDC1 family.
CC {ECO:0000256|ARBA:ARBA00009081}.
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DR RefSeq; XP_001055195.1; XM_001055195.4.
DR RefSeq; XP_001059859.1; XM_001059859.4.
DR RefSeq; XP_001066066.1; XM_001066066.4.
DR RefSeq; XP_229957.2; XM_229957.5.
DR RefSeq; XP_235194.1; XM_235194.4.
DR RefSeq; XP_236761.1; XM_236761.4.
DR STRING; 10116.ENSRNOP00000000215; -.
DR PaxDb; 10116-ENSRNOP00000000215; -.
DR Ensembl; ENSRNOT00000000215.4; ENSRNOP00000000215.3; ENSRNOG00000000199.4.
DR Ensembl; ENSRNOT00000049144.5; ENSRNOP00000041925.4; ENSRNOG00000029793.5.
DR GeneID; 299829; -.
DR GeneID; 301101; -.
DR GeneID; 311031; -.
DR KEGG; rno:299829; -.
DR KEGG; rno:301101; -.
DR KEGG; rno:311031; -.
DR AGR; RGD:1305838; -.
DR AGR; RGD:1559995; -.
DR AGR; RGD:1564306; -.
DR CTD; 299829; -.
DR CTD; 311031; -.
DR CTD; 340168; -.
DR RGD; 1305838; Dppa5.
DR RGD; 1564306; Dppa5al1.
DR RGD; 1559995; Dppa5l1.
DR VEuPathDB; HostDB:ENSRNOG00000000199; -.
DR VEuPathDB; HostDB:ENSRNOG00000032335; -.
DR eggNOG; ENOG502RW7D; Eukaryota.
DR GeneTree; ENSGT00940000154353; -.
DR HOGENOM; CLU_169085_0_0_1; -.
DR OMA; KLRTRWM; -.
DR OrthoDB; 4942317at2759; -.
DR TreeFam; TF338690; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Bgee; ENSRNOG00000029793; Expressed in esophagus and 5 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; ISO:RGD.
DR GO; GO:0003729; F:mRNA binding; ISO:RGD.
DR GO; GO:0010468; P:regulation of gene expression; ISO:RGD.
DR CDD; cd12795; FILIA_N_like; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR031952; MOEP19_KH-like.
DR PANTHER; PTHR31368; DEVELOPMENT PLURPOTENCY-ASSOCIATED PROTEIN 1/5 FAMILY MEMBER; 1.
DR PANTHER; PTHR31368:SF4; DEVELOPMENTAL PLURIPOTENCY-ASSOCIATED 5 PROTEIN; 1.
DR Pfam; PF16005; MOEP19; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002494};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 11..95
FT /note="KH-like RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF16005"
SQ SEQUENCE 116 AA; 13440 MW; 8A525CB283B43FDF CRC64;
MATLVTRKDI PPWVKVPEDL KDPEVFQVHT LVLKSLFGPQ GSRMPHIEQV SRAMFELKIL
ESSGLTEVLI YGSCNHKLRA KWMLQSMAER YRLRQERGML KLEEAMKTLE LGQCLE
//
