ID F1MLU5_BOVIN Unreviewed; 1334 AA.
AC F1MLU5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Scavenger receptor cysteine rich family member with 5 domains {ECO:0000313|Ensembl:ENSBTAP00000041247.4};
GN Name=SSC5D {ECO:0000313|Ensembl:ENSBTAP00000041247.4,
GN ECO:0000313|VGNC:VGNC:35310};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000041247.4, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000041247.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000041247.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000041247.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000041247.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PaxDb; 9913-ENSBTAP00000041247; -.
DR Ensembl; ENSBTAT00000043694.4; ENSBTAP00000041247.4; ENSBTAG00000030885.4.
DR VEuPathDB; HostDB:ENSBTAG00000030885; -.
DR VGNC; VGNC:35310; SSC5D.
DR eggNOG; ENOG502SECN; Eukaryota.
DR GeneTree; ENSGT00940000162592; -.
DR HOGENOM; CLU_004182_0_0_1; -.
DR TreeFam; TF329295; -.
DR Proteomes; UP000009136; Chromosome 18.
DR Bgee; ENSBTAG00000030885; Expressed in pigment epithelium of eye and 84 other cell types or tissues.
DR ExpressionAtlas; F1MLU5; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 5.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 5.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 5.
DR SUPFAM; SSF56487; SRCR-like; 5.
DR PROSITE; PS00420; SRCR_1; 5.
DR PROSITE; PS50287; SRCR_2; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1334
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018609197"
FT DOMAIN 20..120
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 201..301
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 307..407
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 471..572
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 767..867
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT REGION 121..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 417..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..1261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1306..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..462
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..706
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 886..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1016
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1049..1063
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1090
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1120..1261
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 45..109
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 58..119
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 89..99
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 226..290
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 239..300
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 270..280
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 332..396
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 345..406
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 376..386
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 541..551
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 792..856
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 805..866
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 836..846
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1334 AA; 138314 MW; 654CD03AFACB6BF0 CRC64;
MRVLACLLVA LMGTQAVERL RLADGPHGCA GRLEVWHGGR WGTVCDDGWD LRDAAVACRE
LGCGGALAAP GGAFFGEGAG PVWLSELACR GGERQLGLCP HRGWKAHICS HEEDAGVVCA
GQRGTDSRDH DDPPSVLDGD PWPGLAGELS PGSEEAPVTP APRPAGTPQS GSRKKSPRLP
KPAKSTRAPV LTAGAPRQER LRLVSGPHGC AGRLEVWHGG RWGTVCDDGW DLRDAAVACR
ELGCGGALAA PGGARFGPGA GPVWMDDVGC GGGEQALRDC PRSPWGRSNC DHSEDAGLVC
TGPAPRLRLA DGPHGCAGRL EVWHGGRWGT VCDDGWDLRD AAVACRELGC GGALAAPGGA
FFGEGAGPIL LDDLRCRGNE TALRFCPARP WGQHDCHHRE DAGAVCDGMP LGYVPPTAPA
AGSNSSGPRG APSRSPPPTA SQAPQMPGVS VPPAPPTFLQ EPGPDAGSPQ LRLVAGPSRC
SGRLEVWHAG RWGTVCDDGW DLRDTAVVCR ELGCGGPRQS DPTAGRFGWG AGPIWLDDVR
CTGTEAALAD CLAAPWGKHN CAHNEDVGVT CAGTPGLDSI SDPFSWSWIP GLGRDPDAWL
PGELATKPSA RQTPSIPEKT TKAPGKMPKS TKKWVTKNAK RPTTQPPAMP TTKHSRVSGT
QSPPELTSRT TSTLATGASR RPTSEFTTRL TTQAPRRLTS HTTVTRTSRA PRERTSKTVA
TLATQGPRLV TSEATVEPSA ELPGQGSPES STDPAPSPTG AAGPFRVRLA DGPNRCAGRL
EVWHAGQWGT VCDDGWDLRD GMVTCWELGC GRVRPRVGKT HYGPGTGPIW LDDVGCKGSE
SSLSDCPARA WGQHNCDHEE DVGLTCTGYA DEEDYPPWTW DPTSGEDLAK GTTSAGVPGH
TLSRETTGSP GAPTPATRRL PSTGDKDCRE PSRTGDTPSG GVPAKETPTA ATPGPPGTTR
SSGHPSLAPR LRGDTGSQRR RWPERRLRPT TARTKPAAPS PPASAAPGPA DPPLTSASAP
PLIRTAASTP EATPDATSAV PPSPVAASRG SAHRTSTSPG LTGPSPDAAA APAPTSRLSP
TPPPTAPKEL TSDPSAPAAA THLSPTSGLT PDPDKAPGRG TSPQPSTVPE PSSSPDRSTG
PHPTTAPYST MTSHPEPTSH PTTAPYSSMT SHPAATSHPT TAPYSTMTSH PTTALYSTMT
SHPAPTSHPT TAPYTTMTSH PASTSHPTTA PYSTIISHPA ATSHPTTAPY STMTSHPAAA
SHPTTTLYLT STPHATTTPY PTTTPYPTTT PYPTTISHPT VTSHPTSALY PTTTPHATTT
PYPTTTPHST STPH
//
