ID F1MWR0_BOVIN Unreviewed; 665 AA.
AC F1MWR0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 2.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Myotubularin related protein 11 {ECO:0000313|Ensembl:ENSBTAP00000016579.5};
GN Name=MTMR11 {ECO:0000313|Ensembl:ENSBTAP00000016579.5,
GN ECO:0000313|VGNC:VGNC:31738};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000016579.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000016579.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000016579.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000016579.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000016579.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
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DR AlphaFoldDB; F1MWR0; -.
DR SMR; F1MWR0; -.
DR PaxDb; 9913-ENSBTAP00000016579; -.
DR Ensembl; ENSBTAT00000016579.6; ENSBTAP00000016579.5; ENSBTAG00000012496.6.
DR VEuPathDB; HostDB:ENSBTAG00000012496; -.
DR VGNC; VGNC:31738; MTMR11.
DR eggNOG; KOG1089; Eukaryota.
DR GeneTree; ENSGT00940000160276; -.
DR HOGENOM; CLU_021912_1_0_1; -.
DR OMA; GWQRSQD; -.
DR TreeFam; TF315197; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000012496; Expressed in uterine horn and 100 other cell types or tissues.
DR ExpressionAtlas; F1MWR0; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR InterPro; IPR022587; MTMR12-like_C.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF51; MYOTUBULARIN-RELATED PROTEIN 11; 1.
DR Pfam; PF12578; 3-PAP; 1.
DR Pfam; PF06602; Myotub-related; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 168..609
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT REGION 646..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 74629 MW; 6E8D391FECEBE876 CRC64;
MPEPRSRQLG SCLASGGLPG EQILAWAPGV RKGLEPEMPG TLICSNLRVT FQPHGWQRSQ
ETPLSSEYDF SLANIGRLEA VHGPSRVQLL RPGSLLKFIP EEILIHGQDF RLLRVGFEAG
GLEPQAFQVT MAIVQARAQN SPAQQYAGIT LSQAGQSSDS RKPPIPLLET IEDWETERKK
QAARGWRVST VNERFDVATS LPRYFWVPNR TLDSEVRRAF GHFHQGRGPR LSWHHPGGSD
LLRCGGFYTA SDPNKEDIRA VESMLQAGHS DVVLVDTMDE LPSLADVQLA HLRLRALCLP
DSSVAEDKWF SALEGTRWLD YTRSCLRKAS DISVLVTSRV RSVVLQERGD RDFNGLLSSL
VQLLSAPEAR TLLGFQSLVQ REWVAAGHPF LTRLGGSGAS EEAPVFLLFL DCVWQLLQQF
PAEFEFSEFF LLALHDSVRV PDTLTFLRDT PWERGKQSGQ FNNYTQVYTP GFPGAGNSIN
PQLSVWDWNL RYSNKQILQF RNPGYDPEHC PDSWLPRQQP SFMVPGPPSS VWLFSRGSLT
PLNQLCPWRD SPSLLAVSSR WLPRPAISSE SLADQEWGLP SHWGACPLPP GLLLPGCLGP
QIRLWRRCYL RGRPEVQMGL SAPTISGLQE ELSHLQELLR KWTPRISPED HSKRRNPNTI
LSQSR
//
