ID F1N1W5_BOVIN Unreviewed; 328 AA.
AC F1N1W5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Nitrilase 1 {ECO:0000313|Ensembl:ENSBTAP00000026843.5};
GN Name=NIT1 {ECO:0000313|Ensembl:ENSBTAP00000026843.5,
GN ECO:0000313|VGNC:VGNC:32089};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000026843.5, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000026843.5, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000026843.5,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000026843.5}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000026843.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC NIT1/NIT2 family. {ECO:0000256|ARBA:ARBA00010613}.
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DR AlphaFoldDB; F1N1W5; -.
DR SMR; F1N1W5; -.
DR Ensembl; ENSBTAT00000026843.6; ENSBTAP00000026843.5; ENSBTAG00000020153.6.
DR VEuPathDB; HostDB:ENSBTAG00000020153; -.
DR VGNC; VGNC:32089; NIT1.
DR GeneTree; ENSGT00550000075099; -.
DR HOGENOM; CLU_030130_1_1_1; -.
DR OMA; MRVAVCQ; -.
DR TreeFam; TF313080; -.
DR Proteomes; UP000009136; Chromosome 3.
DR Bgee; ENSBTAG00000020153; Expressed in semen and 102 other cell types or tissues.
DR ExpressionAtlas; F1N1W5; baseline and differential.
DR GO; GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:InterPro.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR CDD; cd07572; nit; 1.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR045254; Nit1/2_C-N_Hydrolase.
DR InterPro; IPR001110; UPF0012_CS.
DR PANTHER; PTHR23088:SF27; DEAMINATED GLUTATHIONE AMIDASE; 1.
DR PANTHER; PTHR23088; NITRILASE-RELATED; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS01227; UPF0012; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 47..299
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 328 AA; 36222 MW; BF0990AF2CC0FEBF CRC64;
MLGFIIRPPH QLLSLLSCPG LRIPRFSVLC APPRLRTMAA SSSFSELPLV AVCQVTSTPD
KEQNFKTCAE LIREAARLGA CLAFLPEAFD FIARDPEETR RLSEPLSGNL LEEYTQLARE
CGLWLSLGGF HERGQDWEQT QKIYNCHVIL NNMGSVVATY RKTHLCDVEI PGQGPMRESN
STIPGPSLES PISTPAGKIG LAICYDMRFP ELSLALVQAG AEILTYPSAF GSVTGPAHWE
VLLRARAIET QCYVVAAAQC GRHHEKRASY GHSMVVDPWG TVVARCSEGP GLCLARIDLN
YLQQLRKQLP VFQHRRPDLY GNLGHPLS
//
