ID F1N6D0_BOVIN Unreviewed; 456 AA.
AC F1N6D0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 3.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=WAP domain-containing protein {ECO:0000259|PROSITE:PS51390};
GN Name=LOC515676 {ECO:0000313|Ensembl:ENSBTAP00000045198.4};
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000045198.4, ECO:0000313|Proteomes:UP000009136};
RN [1] {ECO:0000313|Ensembl:ENSBTAP00000045198.4, ECO:0000313|Proteomes:UP000009136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000045198.4,
RC ECO:0000313|Proteomes:UP000009136};
RA Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT "ARS-UCD1.2.";
RL Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSBTAP00000045198.4}
RP IDENTIFICATION.
RC STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000045198.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010796415.2; XM_010798113.2.
DR RefSeq; XP_010814086.2; XM_010815784.2.
DR AlphaFoldDB; F1N6D0; -.
DR Ensembl; ENSBTAT00000048100.4; ENSBTAP00000045198.4; ENSBTAG00000025258.5.
DR GeneID; 515676; -.
DR VEuPathDB; HostDB:ENSBTAG00000025258; -.
DR eggNOG; KOG1217; Eukaryota.
DR GeneTree; ENSGT00940000168945; -.
DR HOGENOM; CLU_613312_0_0_1; -.
DR InParanoid; F1N6D0; -.
DR OMA; CCKNSCG; -.
DR TreeFam; TF338375; -.
DR Proteomes; UP000009136; Chromosome 19.
DR Bgee; ENSBTAG00000025258; Expressed in spermatid and 92 other cell types or tissues.
DR ExpressionAtlas; F1N6D0; baseline and differential.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IBA:GO_Central.
DR GO; GO:0019731; P:antibacterial humoral response; IBA:GO_Central.
DR GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR CDD; cd00199; WAP; 1.
DR Gene3D; 3.30.40.170; -; 9.
DR Gene3D; 4.10.75.10; Elafin-like; 1.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR008197; WAP_dom.
DR PANTHER; PTHR19441:SF91; WAP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19441; WHEY ACDIC PROTEIN WAP; 1.
DR Pfam; PF00095; WAP; 5.
DR PRINTS; PR00003; 4DISULPHCORE.
DR SMART; SM00286; PTI; 6.
DR SMART; SM00217; WAP; 6.
DR SUPFAM; SSF57256; Elafin-like; 1.
DR PROSITE; PS51390; WAP; 5.
PE 4: Predicted;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000009136}.
FT DOMAIN 106..153
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 174..221
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 242..289
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 346..395
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 399..446
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
SQ SEQUENCE 456 AA; 48419 MW; 990DF746EE7EFF62 CRC64;
MQARLSVQQC INLSCLSLTH VPRLHMMSST SNMKLGGLFL LASLLTLNTR LQAIGVCVEQ
CREDQDCVAG EKCISNGCGH VCSPAPQATI CSLECSEDRD CGRGKQCVQD GCQRVCSPLM
SVGICVEQCR EDQDCAAGEK CISNGCGHVC SPVPQATICS LECSEDRDCG RGKQCVQDGC
QRVCSPLMSV GVCVEQCRED QDCAAGEKCV SNGCGHVCSP VPQATICSRE CSEDRDCGRG
KQCVQDGCRR VCSPLMSVGV CVEQCREDRD CAAGEKCVSN GCGHVCSPAP QASICEFQCF
RDRDCGAGRQ CVSEGCNRVC SPAPEASIGI CVQRCRGHWD CGAGERCIRR GCSRICSPVR
TAGVGICLDQ CQGHRDCPAG SRCVSNGCGR VCSPTQDRQE QRPGTCPRVP EGMFGTCAER
CTGDGSCPPG QKCCSNGCGK SCQVPDLDFT ISLDDK
//
